PubMed Health⌕ Search

Biomedical subjects

T Fukutome

Publications and source records attributed to T Fukutome.

27 records · Page 2Linked to original sources
PubMed1986

Prediction of subclavian vein location using plain chest radiography.

The relationship between the right subclavian vein and the thoracic inlet below the clavicle was studied by Venography in 72 patients. The area of the thoracic inlet below the clavicle was defined as a radiolucent area surrounded superiorly by the lower border of the clavicle, inferiorly by the inner margin of the first rib and medially by the lateral margin of the manubrium (CRM area). In 10 patients, the subclavian vein was situated below the axis of the clavicle, and the CRM area was large enough to extend near the top of the first rib arch. In 62 patients, the subclavian vein extended above the axis of the clavicle and the CRM area was small or invisible. The existence of a large thoracic inlet below the clavicle (large CRM area which extends near the top of the first rib arch) may be a useful indicator for predicting the low location of the subclavian vein, and may be used to predict or explain venipuncture failure using the standard infraclavicular approach.

Adult↗
PubMed1986

Isolation of a peptide material showing strong rectal muscle-contracting activity from chicken rectum and its identification as chicken neurotensin.

A peptide with strong activity to contract isolated whole chick rectum, RC-substance, in an acid-acetone extract prepared from 2.0 kg wet weight of chicken rectums was isolated by gel filtration on Sephadex G-25, ion exchange chromatography on a SP-Sephadex C-25 column, and high voltage paper chromatography. The close purity of this substance was established by high performance liquid chromatography (HPLC). The RC-substance displayed the same pharmacological and enzymatic properties as bovine neurotensin (NT). However, it differed from bovine NT in its behavior during the ion exchange chromatography, in its mobility during the electrophoresis, and in its retention time on HPLC. The amino acid analysis by a conventional OPA method revealed that all ten amino acid residues of which molar ratios were integral were common with those of chicken NT. Its biological activities were equipotent to those of bovine NT, suggesting the presence of proline in the COOH-terminal hexapeptide. From these results, it can be concluded that the RC-substance is identical to chicken NT. Exposure to high concentrations of bovine NT rendered the rectal smooth muscle of the chicken insensitive to subsequent applications of the RC-substance as well as bovine NT. This desensitization also reduced specifically the contractile responses of the rectal muscle elicited by non-adrenergic and non-cholinergic (NANC) nerve stimulation, suggesting a possible physiological role of the RC-substance as the neurotransmitter of NANC neurones.

Amino Acids↗
PubMed1980

Importance of antiserum and phagocytic cells in the protection of mice against infection by Klebsiella pneumoniae.

Rabbit antiserum to Klebsiella pneumoniae showed a powerful protective effect against intramuscular infection in normal mice. No protective effect was observed in mice whose monocytes and polymorphonuclear cells were depleted by X-irradiation. The antiserum had approximately the same protective effect in mice whose macrophages were blocked selectively by carrageenan as in normal mice. It is concluded that antiserum exerted its effect by opsonic function and that opsonized K. pneumoniae were eliminated mainly by polymorphonuclear cells rather than macrophages, at least in an early phase of the infection. these findings were supported by histological examination and observation of intracellular killing in vitro.

Animals↗