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T G Bömer

Publications and source records attributed to T G Bömer.

4 recordsLinked to original sources
PubMed1996

Pattern electroretinogram and computerized optic nerve-head analysis in ocular hypertension--interim results after 2.5 years.

Evidence exists that both the pattern electroretinogram (PERG) as a parameter of ganglion-cell function and computerized morphometric disc analysis (ONHA) predict subsequent glaucomatous visual field defects in ocular hypertensive eyes. Since November 1991 we have conducted a prospective longitudinal study to evaluate the suitability of PERG and ONHA for detecting incipient glaucoma damage. Inclusion criteria were: an intraocular pressure of > or = 25 mmHG (at least two measurements taken on different days) or, in eyes with additional risk factors, > or = 23 mmHG; a normal Octopus visual field (mean defect < or = 2 dB, no local defect); and no definite glaucomatous disc cupping. After a mean follow-up period of 14.6 +/- 8.8 (range 1-33) months and with a mean intraocular pressure of 24.4 (range 18-42) mmHg, none of the 66 patients (115 eyes) converted to glaucoma. Furthermore, PERG and ONHA do not agree in their estimation of the glaucoma risk at this stage.

Electroretinography↗
PubMed1995

[Increased intraocular pressure after cataract extraction--effect of surgical technique, surgical procedure and preventive drug administration. A prospective, randomized double-blind study].

BACKGROUND: We performed a double-masked, randomized and prospective study to compare the effect of surgical technique, surgeon's experience, and prophylactic medication on the intraocular pressure rise after cataract extraction. PATIENTS AND METHODS: Intraocular pressure of 120 patients was measured the day before, as well as two to four, five to seven and 22 to 24 hours after uncomplicated cataract extraction. 47 patients were operated with phacoemulsification and sclerocorneal sutureless tunnel (phaco/tunnel). 61 patients with phacoemulsification and corneoscleral incision and suture (phaco/suture), and 12 patients with extracapsular technique (ECCE). 48 operations were done by inexperienced surgeons (less than 200 intraocular operations), 72 by experienced surgeons (300-2000 intraocular operations). Patients were treated with either levobunolol, acetazolamide, apraclonidine, or placebo. Each treatment group contained 30 patients. RESULTS: In all groups, the mean intraocular pressure increased to a maximum at five to seven hours after surgery. The pressure rise was significantly higher in the ECCE group (20.6 mm Hg) than in the phaco/suture group (10.5 mm Hg) and in the phaco/tunnel group (5.4 mm Hg, p always < 0.05). Eyes operated by inexperienced surgeons had a significantly (p < 0.005) greater pressure rise (12.9 mm Hg) than eyes operated by experienced surgeons (7.1 mm Hg). Treatment had no significant (p = 0.41) effect on the intraocular pressure rise. CONCLUSION: The intraocular pressure rise after cataract extraction strongly depends on the surgical technique and to a lesser extent, on the surgeon's experience. At least for phacoemulsification, the effect of the prophylactic medication used in this study is small and appears to be clinically irrelevant.

Acetazolamide↗
PubMed1995

Intraocular pressure rise after phacoemulsification with posterior chamber lens implantation: effect of prophylactic medication, wound closure, and surgeon's experience.

AIMS: A prospective clinical trial was carried out to evaluate the effect of prophylactic medication, the technique of wound closure, and the surgeon's experience on the intraocular pressure rise after cataract extraction. METHODS: In 100 eyes, the intraocular pressure was measured before as well as 2-4, 5-7, and 22-24 hours after phacoemulsification and posterior chamber lens implantation. Each of 25 patients received either 1% topical apraclonidine, 0.5% topical levobunolol, 500 mg oral acetazolamide, or placebo. Forty four eyes were operated with sclerocorneal sutureless tunnel and 56 eyes with corneoscleral incision and suture. Sixty three operations were performed by experienced surgeons (more than 300 intraocular operations) and 37 by inexperienced surgeons (less than 200 intraocular operations). RESULTS: The pressure increase from baseline to the maximum 5-7 hours after surgery did not differ significantly (p = 0.8499) for apraclonidine (9.5 mm Hg), levobunolol (7.2 mm Hg), acetazolamide (7.8 mm Hg), and placebo (8.6 mm Hg). The increase was significantly (p = 0.0095) lower in eyes with corneoscleral tunnel (5.5 mm Hg) than in eyes with corneoscleral suture (10.5 mm Hg) and significantly (p = 0.0156) lower for experienced (6.6 mm Hg) than for inexperienced surgeons (11.2 mm Hg). CONCLUSIONS: The intraocular pressure rise after phacoemulsification and posterior chamber lens implantation depends strongly on the technique of wound closure and the surgeon's experience. Compared with these two factors, the effect of prophylactic medication can be neglected.

Acetazolamide↗