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Biomedical subjects

T G Lowe

Publications and source records attributed to T G Lowe.

5 recordsLinked to original sources
PubMed1994

A prospective analysis of autograft versus allograft in posterolateral lumbar fusion in the same patient. A minimum of 1-year follow-up in 144 patients.

STUDY DESIGN: One hundred forty four patients who underwent lumbar spine fusions had autografts placed on one side as a control and on the opposite side one of the following types of graft material was placed: iliac autograft, demineralized cancellous chips, demineralized cortical powder, demineralized cortical powder mixed with autograft, or mineralized cancellous chips. Alar anteroposterior and lateral postoperative radiographs were reviewed by three independent observers and graded for quality of fusion mass bilaterally. The follow-up was 14 to 27 months. OBJECTIVES: This study evaluated the efficacy of various types of ethylene oxide-sterilized allograft bone used for spine fusions and compared them with autograft iliac bone in the same patient. SUMMARY OF BACKGROUND DATA: Previous studies comparing autograft with allograft showed poorer fusion rates with allograft with posterior fusions. Most of the previous studies included smaller numbers of patients. No previous studies compared ethylene oxide-treated allograft with autograft. RESULTS: An analysis of the radiographs at a minimum of 1 year postoperatively revealed significantly lower values when allograft alone or in combination with autograft was used in comparison to autograft alone. CONCLUSIONS: Ethylene oxide-treated allograft is inferior to autograft and should not be used for posterior lumbar fusions.

Adult↗
PubMed1994

An analysis of sagittal curves and balance after Cotrel-Dubousset instrumentation for kyphosis secondary to Scheuermann's disease. A review of 32 patients.

STUDY DESIGN: This study compared preoperative and postoperative saggittal curves and spinal balance in patients undergoing spinal fusion with Cotrel-Dubousset instrumentation for severe kyphosis secondary to Scheuermann's disease. Also determined was patient satisfaction regarding relief of pain and correction of the deformity. Thirty two patients with kyphosis > 75 degrees underwent spinal fusion with Cotrel-Dubousset instrumentation. OBJECTIVES: To evaluate the initial and long-term correction of the primary kyphosis and changes in lumbar lordosis and sagittal balance, and to determine the incidence and etiology of junctional sagittal deformities. SUMMARY OF BACKGROUND DATA: The average preoperative kyphosis was 85 degrees (range, 75 degrees to 105 degrees) with an average correction at final follow-up of 43 degrees (range, 26 degrees to 65 degrees). Preoperative lumbar lordosis averaged 75 degrees (range, 58 degrees to 100 degrees) and at final follow-up averaged 55 degrees (range, 23 degrees to 74 degrees). Most of the patients demonstrated negative sagittal balance and became slightly more negatively balanced postoperatively. RESULTS: Maintenance of correction postoperatively was excellent, with only a 4 degree average loss of correction. There was spontaneous reduction in lumbar lordosis of varying degrees. Proximal junctional kyphosis was associated with over-correction (> 50%) of the kyphotic deformity or a fusion starting short of the proximal vertebra in the measured kyphosis. Distal junctional kyphosis developed in patients whose fusion ended short of the first lordotic segment. CONCLUSIONS: This procedure appeared to yield good results when proper levels of fusion were selected and correction > 50% was not attempted.

Adult↗
PubMed1993

Anterior spinal fusion with Zielke instrumentation for idiopathic scoliosis. A frontal and sagittal curve analysis in 36 patients.

The authors have reviewed the records of 36 patients with idiopathic scoliosis who underwent a single-stage anterior spinal fusion with Zielke instrumentation to determine if any adverse frontal or secondary sagittal deformities or changes in balance resulted from the surgery. Spontaneous correction of uninstrumented thoracic curves was noted in five patients with double-major curves, and frontal balance was maintained or improved after operation in all but four patients. Kyphosis was increased in the instrumented segments in all patients. In the uninstrumented segments, however, thoracic kyphosis and lumbar lordosis were decreased in all but five patients after operation, whereas overall sagittal balance was not adversely affected by the surgery in any patient.

Adolescent↗
PubMed1987

Double L-rod instrumentation in the treatment of severe kyphosis secondary to Scheuermann's disease.

Patients with untreated kyphosis secondary to Scheuermann's disease occasionally develop significant deformities associated with pain in adult life. When these painful deformities do not respond to conservative measures, surgery may be indicated. This report describes a two-stage surgical technique for correction of the deformity. First, an anterior spinal release and fusion is performed and is followed 7-10 days later by a posterior spinal fusion with double L-rod instrumentation. L-rod instrumentation has the advantage that no postoperative immobilization is necessary, which allows the patient to return to a relatively normal life-style in the immediate postoperative period. Excellent maintenance of correction of the deformity in these patients has occurred with no serious complication to date in 24 patients followed from 19 months to 4 years although "transient hyperesthesia" occurred in 16% of patients. A longer follow-up will be necessary to evaluate fully possible late pseudarthrosis and instrumentation failure in this group of patients.

Adolescent↗