Biomedical subjects
T G Owsley
Publications and source records attributed to T G Owsley.
Tumescent technique in cervicofacial rhytidectomy.
The tumescent technique of local anesthetic administration was originally spawned by the desire to facilitate full-body, large volume liposuction in a safe and efficient outpatient manner. The numerous advantages of this technique are readily applied to cervicofacial rhytidectomy. The method described creates an essentially bloodless field via hydrodissection with overall decreased surgical morbidity secondary to the decreased necessity of sharp surgical dissection.
The use of Gore-Tex for nasal augmentation: a retrospective analysis of 106 patients.
Numerous implant materials have been used in nasal surgery, including autogenous, homogeneous, and alloplastic grafts. Autogenous cartilage remains the ideal graft material; however, situations exist where an alternative or an additional grafting material is needed. Homogeneous materials have demonstrated significant resorption. Alloplastic grafts have offered varying degrees of success but have resulted in significant complications as well. Gore-Tex has undergone extensive research and clinical application in various surgical fields with reported success. This analysis examines 106 patients over a 5-year time period in which the Gore-Tex soft-tissue patch was used in a wide variety of situations from extensive nasal dorsal reconstruction to small localized nasal defects or irregularities. Postoperative follow-up has revealed a stable implant material with no complications relating to the graft material.
The effectiveness of flumazenil in reversing the sedation and amnesia produced by intravenous midazolam.
In this double-blind study 31 outpatients undergoing third molar extraction were randomly assigned to one of two groups. All patients were sedated with intravenous midazolam (IV) by titration method. The flumazenil group (n = 20) received an average of 0.8 +/- 0.17 mg of flumazenil IV. The placebo patients (n = 11) each received 10 mL of normal saline. By both observer and patient alertness ratings, patients receiving flumazenil appeared significantly more alert than placebo patients at 5, 15, 30, and 60 minutes following reversal. After reversal the flumazenil group had significantly higher scores than the placebo group at all intervals through 60 minutes. All the patients receiving flumazenil were able to walk without assistance at 5 minutes, compared with only one patient in the placebo group, and more patients in the flumazenil group recognized the picture card shown to them at 5, 15, 30, and 60 minutes postreversal. Flumazenil is effective in terminating the amnestic properties of midazolam, but this appears to occur to a lesser extent than the reversal of its sedative properties.