Biomedical subjects

T Gómez-Cía

Publications and source records attributed to T Gómez-Cía.

11 recordsLinked to original sources

PubMed1999

Mortality according to age and burned body surface in the Virgen del Rocio University Hospital.

The application of updated clinical protocols for the treatment of burned patients is showing very good results. The mortality curves according to age and the percentage of burned body surface could be of great use for the comparison of clinical results between different burns units. The probability of survival in 1000 consecutive patients admitted to the Burns Unit of the Virgen del Rocio University Hospital between July, 1993 and August, 1997, is compared, by graphic analysis, with the mortality curves of other centers, obtaining similar results. We conclude that the results of medical attendance in our unit are in line with those considered as a reference.

Adolescent↗

PubMed1999

Digital imaging in remote diagnosis of burns.

Images are capable of giving an accurate representation of skin color and have been used extensively in teaching about and researching burn therapy. The advance from analogue to digital imaging allows the remote transmission of the clinical information contained in the digital image of a burn, using a suitable system. The large size of these image files reduces transmission speed and makes data compression desirable. Compression, by means of the JPEG algorithm, of up to 50 times the original size of 38 digital images of burns suffered by 22 consecutive patients did not lessen its great usefulness in determining the depth of burn injuries, according to a group of experts in burn care. The success rate was close to 90%, both for non-compressed images in original BMP format (mean size:1500 Kb) and for compressed images with a Q index of 50 (30 Kb files), when compared with the clinical diagnoses confirmed one week after the accident.

Adult↗

PubMed1999

Analysis of flow changes in forearm arteries after raising the radial forearm flap: a prospective study using colour duplex imaging.

The purpose of this study is to assess the changes in flow patterns of forearm arteries produced by excision of the radial artery when harvesting the radial forearm flap, in order to clarify its vascular morbidity rationally. Eleven patients with elective surgery using the radial flap were included in this investigation. A prospective study was designed using colour duplex imaging for quantitative flow measurement in two stages: a few days before the operation, a first colour duplex scanning examination was done recording flow velocity and vessel section area from the radial, ulnar, posterior interosseous and anterior interosseous arteries around the wrist. Volumetric parameters and relative blood flow percentages were calculated and compared to those obtained from a second similar vascular investigation accomplished in the same limb 4-5 months after the operation. Statistical analysis was done using the Wilcoxon matched pairs test. After raising the radial forearm flap there was a trend for increased overall forearm flow (from 162 to 215 ml/min, P = 0.09 N.S.), the ulnar (P = 0.04), the posterior interosseous (P = 0.004) and the anterior interosseous (P = 0.003) arteries being responsible for this tendency. The anterior interosseous artery showed the greatest increase in blood (from 8.2 to 67.7 ml/min), reaching a relative flow percentage (33%) close to that of the radial artery before its excision (39%). Results of this study indicate that another 'major vascular axis' based on the anterior interosseous artery develops after sacrificing the radial artery and that global arterial inflow to the hand is not impaired.

Arteries↗

PubMed1999

Flow changes in forearm arteries after elevating the radial forearm flap: prospective study using color duplex imaging.

The aim of the present study was to assess the changes in flow patterns of forearm arteries produced by excision of the radial artery when harvesting the radial forearm flap. A prospective study using color duplex imaging for quantitative flow measurements was accomplished in 11 patients. After raising the radial flap, the forearm flow tended to increase overall, the ulnar (P = 0.04), the posterior interosseous (P = 0.003), and the anterior interosseous (P = 0.003) arteries being responsible for this tendency. Therefore, harvesting of a radial flap must not be considered as causing vascular morbidity in terms of blood supply to the hand.

Angiography↗

PubMed1998

Angiologic observations following radial artery flap elevation: a case report.

Since the introduction of the radial forearm flap in 1981, its inherent vascular morbidity in sacrificing the radial artery has been strongly criticized. In the present paper, a case report is presented where postoperative angiography showed an important contribution of the anterior interosseous artery to hand vascularity two years after raising a reverse flow distally based pedicle radial forearm flap for dorsal hand resurfacing. In order to analyze this finding, further vascular investigations using Color Duplex Imaging examinations for quantitative flow measurements comparing blood flow rates in both right and left forearm arteries were carried out in this patient. Contrary to expectations, results from vascular examinations revealed that overall blood flow in donor forearm arteries was greater than in the contralateral forearm, the anterior interosseous artery showing the greatest difference in blood flow. These data seem to indicate that another major vascular axis based on the anterior interosseous artery develops after removing the radial artery when harvesting the radial forearm flap and that global arterial inflow to the hand is not impaired.

Angiography↗

PubMed1997

Bacteremia caused by Leuconostoc cremoris in a patient with severe burn injuries.

A case of Leuconostoc cremoris bacteremia in a patient with burn wounds over 45% of the body surface is presented. Leuconostoc bacteremia has not previously been reported in burn patients. The predisposing factors in this case were severe burn wounds resulting in immunocompromise, presence of both intravenous and enteral feeding catheters, several surgical interventions and previous treatment with imipenem plus amikacin. The patient was successfully treated with ampicillin 2 g l.v. every 6 hours for 21 days. Infection with Leuconostoc should be suspected when vancomycin-resistant organisms resembling streptococci are isolated.

Adult↗

PubMed1997

Esophageal obstruction by solidification of the enteral feed: a complication to be prevented.

We report three cases of esophageal obstruction due to solidification of enteral feed refluxed from the stomach in patients being fed through a nasogastric tube. All three patients were administered sucralfate continuously by tube. The few previous descriptions of this rare complication have also implicated sucralfate with its pathogenesis. Given its clinical importance and the growing use of long-term enteral nutrition, this adverse event needs to be considered.

Adult↗

PubMed1993

A burn patient resuscitation therapy designed by computer simulation (BET). Part 1: Simulation studies.

This study presents an analysis of the fluid, electrolyte and colloid needs of burn patients during the shock phase. A digital simulation technique was used which had previously been validated and published in burned patients (Roa et al., 1988). After analysing the repercussions of both burns and various resuscitation procedures, a fluid therapy method (BET) has been designed using a burn patient simulator, which has been characterized by its effectiveness and minimal side-effects. The characteristics of the BET method are a low volume of infusion resuscitation solution (220 ml/h/m2 burned body surface area (BBSA)) and a rapid and large volume of colloidal substances (with colloid concentrations of 10, 7.5 and 5 g/100 ml during the first three 8 h periods of the first postburn day and 2.5 g/100 ml until the 40th h postburn).

Burns↗

PubMed1993

A burn patient resuscitation therapy designed by computer simulation (BET). Part 2: Initial clinical validation.

The clinical results obtained from the first 40 burned patients resuscitated with 220 ml/h x BBSA (m2) of human serum albumin with concentrations of 10, 7.5, 5 and 2.5 per cent in lactated Ringer's (0-8, 8-16, 16-24 and 24-40 h post injury respectively), which we have called BET fluid therapy, were compared with those obtained in 58 patients resuscitated with lactated Ringer's 4 ml/kg of body weight/%BBSA during the first 24 h after burning. The results confirm the effectiveness of the BET form of fluid therapy during the shock phase after burning. The BET fluid therapy method differs from other procedures because of its lower volume of infused resuscitation solution with the rapid infusion of large amounts of colloid. These preliminary results have encouraged us to continue analysing this new method of fluid therapy.

Adolescent↗

PubMedDate not supplied

[Enteral nutrition in burn patients].

UNLABELLED: Nutritional support plays an important role in the treatment of patients with burns. Due to the severe hypercatabolism that develops in these patients, oral support is insufficient in most cases, and this makes it essential to initiate artificial nutritional support (either enteral or parenteral). Enteral nutrition is more physiological than parenteral, and data exist which show that in patients with burns, enteral nutrition exercises a protective effect on the intestine and may even reduce the hypermetabolic response in these patients. The purpose of the study was to evaluate the effectiveness and tolerance of enteral nutritional support with a hypercaloric, hyperproteic diet with a high content of branched amino acids in the nutritional support of patients suffering from burns. MATERIAL: The study included 12 patients (8 males and 4 females), admitted to the Burns Unit. Average age was 35 +/- 17 years (range: 21-85 years). The percentage of body surface affected by the burns was 10% in two cases, between 10-30% in three cases, between 30-50% in five cases and over 50% in two cases. Initiation of the enteral nutrition was between twenty-four hours and seven days after the burn. The patients were kept in the unit until they were discharged, and the average time spent in the unit was 31.5 days (range: 17-63 days). Total energetic requirements were calculated based on Harris-Benedict, with a variable aggression factor depending on the body surface burned, which varied from 2,000 and 4,000 cal day. Nitrogenous balance was determined on a daily basis, and plasmatic levels of total proteins, albumin and prealbumin on a weekly basis. RESULTS: There was a significant difference between the prealbumin values at the initiation and finalization of the enteral nutrition (9.6 +/- 2.24 mg/dl compared with 19.75 +/- 5.48 mg/dl; p < 0.001). The nitrogenous balance improved, changing from -5.4 in the second week to positive values by the fourth and fifth weeks of treatment. Tolerance to the enteral diet was very good, and only mild complications such as diarrhoea developed in two patients. CONCLUSIONS: Enteral nutrition is a suitable nutritional support method for patients with burns, which maintains the nitrogenous balance positive and improves the visceral protein parameters in these patients at an early stage, with very few complications.

Adult↗

PubMedDate not supplied

[Insulin-like growth factor I as a marker of nutritional status in patients on enteral nutrition].

In order to appraise type 1 insulin growth factor (IGF-1) as nutritional state marker in comparison with other known markers, seric IGF-1 (RIA), albumin, prealbumin, transferrin and retinol-bound protein were determined weekly in 15 patients with oropharyngeal neoplasm and 7 in the burns unit, all being administered enteral nutrition. At the beginning of the study, IGF-1 seric levels were significantly lower in the burns group compared with the neoplasm group (82.28 +/- 23.36 vs 137.58 +/- 66.2 ng/ml, p < 0.01). IGF-1 values in the first group were initially significantly lower in comparison with those for the same group at the end of the study (82.28-23.36 vs 177.11 +/- 53.87 ng/ml, p < 0.01 for paired data). No significant change was demonstrated in IGF-1 seric levels in the neoplasm group. IGF-1 seric levels showed a significant multiple correlation with albumin, prealbumin, transferrin and retinol-bound protein in both the group with burns (r = 0.696, p < 0.001) and that with neoplasms (r = 0.615, p < 0.001). The nitrogen balance revealed a univariant and significant linear correlation with IGF-1 (r = 0.373, p < 0.05) and with prealbumin (r = 0.377, p < 0.05). According to the data obtained, seric IGF-1 has a significant correlation with other well-known nutritional markers. In the burns group, the hypercatabolism was accompanied by a significant increase in seric IGF-1 levels.

Adolescent↗