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Biomedical subjects

T Ghini

Publications and source records attributed to T Ghini.

11 recordsLinked to original sources
PubMed1990

Effects of sport (football) on growth: auxological, anthropometric and hormonal aspects.

There are very few data available on the relationship between sporting activities, endocrine levels and changes in anthropometric measurements during growth. In order to study these relationships, we have made measurements of growth, changes in physical conformation and the plasma levels of several hormones [cortisol, dehydroepiandrosterone sulphate (DHEA-S), testosterone, growth hormone, somatomedin C, insulin, glycaemia and haemoglobin A1C] in 175 boys, aged 10-16 years, who have played football at a competitive level and in 224 boys, severing as controls, who have never performed sporting activities regularly. The football players were divided into prepubertal and pubertal subjects (10-11.99 years, 12-13.99 years and 14-16 years, chronological and bone age groups). Our results showed no significant differences in the growth indices between prepubertal athletes and controls, but the plasma level of DHEA-S was significantly higher (P less than 0.05) in the athletes. Pubertal football players, however, were significantly taller than the control subjects, particularly at 14-16 years chronological age. There were no such significant differences when bone age was considered. The pubertal football players were also more advanced in all biological indices of maturity, i.e. pubic hair, testicular volume and bone age. The increase in DHEA-S in pubertal football players, already seen in prepubertals, was also combined with a significant increase in testosterone, growth hormone and cortisol levels. Thus, in football players the DHEA-S level is already higher during prepuberty. This increase thus precedes all other indices of growth and maturation associated with puberty. We hypothesize that, while not excluding the possible influence of selection, as ours is a cross-sectional study, adrenal hyperactivity may be mainly responsible for the earlier onset of pubertal growth and maturity in exercising males.

Adolescent↗
PubMed1989

Growth and sport.

In order to investigate sport's influence on growth during puberty, we examined 398 boys 10-16 yr old. 192 of these subjects had been playing football as a competitive sport, and 206 were considered as controls, having never practised sports regularly. Both groups were divided into prepubertal (with testicular volume less than or equal to 2.5 cc) and pubertal, with the latter further divided into the following chronological and bone age groups: 10-11.99, 12-13.99, 14-16 yr. In these subjects we evaluated auxological-anthropometric and biological maturity characteristics and endocrine parameters (cortisol, dehydroepiandrosterone sulphate, testosterone). No significant difference was found between prepubertal athletes and controls concerning anthropometric and biological maturation parameters, whereas testosterone basal levels were significantly lower (p less than 0.05) and DHEAS values were significantly higher (p less than 0.05). Pubertal football players were significantly taller than controls (particularly at 14-16 yr chronological age), with a greater biacromial diameter after 12 yr chronological and bone age and thinner skinfolds at 12-13.99 chronological and bone age. They were more advanced in all biological maturation parameters i.e. pubic hair, testicular volume and bone age, particularly those subjects playing football for the greatest number of years and training time. In pubertal football players the increase in DHEAS (p less than 0.05) already seen in prepubertals is also combined with a significant increase in testosterone (p less than 0.0001) and cortisol (p less than 0.05). Thus football players DHEAS is already higher during prepuberty and this increase chronologically precedes the advance in all the auxological-maturative parameters typical of our pubertal subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMedDate not supplied

[Are metoclopramide dystonias familial?].

Metoclopramide is an antiemetic drug; the effects on CNS (acute dystonic reaction, tardive dyskinesia, parkinsonism) occur in only 1 of 500 patients treated. Acute dystonic reactions are not apparently dose-dependent and suggest individual sensitivity to the drug (idiosyncrasia). We report 4 cases in 2 families (grandmother-grandchild; brother-sister). We feel that, if there is a case of dystonic reaction to metoclopramide, this drug should not be administered to other members of the same family.

Adolescent↗
PubMedDate not supplied

[Opinions and attitudes of youngsters about sexually transmitted diseases].

A group of 1.085 students (582 M, 503 F) attending high school (742) and nursing school (343) filled in an anonymous questionnaire on their sexual habits and their knowledge of contraception and sexually transmitted diseases. Overall, 57% of the study population had already a complete sexual intercourse at a mean age of 16,4 (SD +/- 1,8). 74% had 1-3 sexual partners, whereas 28% had more than 3. All students affirmed that it was possible to prevent sexually transmitted diseases and 92,6% indicated correct methods. However 10% of students did not know that AIDS is transmitted sexually as 47% hepatitis B. The responses made by nursing students were more correct that those of high school students.

Adolescent↗
PubMedDate not supplied

[Hospital admissions in a pediatric department].

Admission of 429 children in Pediatric Department were examined. 249 children had been taken to emergency ward by parents, 131 had been hospitalized by other physician. 175 children had been examined before admission by panel doctor who decided admission of 114 in Pediatric Department. Parents decided admission of 30 children. The necessity of admission in Department was only in 33 per cent of children admitted.

Female↗
PubMedDate not supplied

[Congenital testicular torsion: a true emergency?].

In the following article the description of four cases of congenital testicular testis, which attend to be under our observation, is reported. Moreover, the diagnostic process is discussed, with particular reference to echography. Afterwards, the method for early surgical exploration is evaluated. The survey concludes that echographic inquiry does not have to be judged indispensable.

Emergencies↗
PubMedDate not supplied

[Spasmus nutans. A re-emergent pathology?].

The authors report two cases of spasmus nutans (a clinical syndrome peculiar to infancy the complete form of which is characterised by nystagmus, rhythmic head movements and wryneck) in two extra-EEC infants. The following elements were present in both patients: scarce exposure to light, early introduction of whole cow's milk, rachitic stigmata, dark skin, poor socio-economic conditions and rapid and complete remission of symptoms following daily exposure to sunlight. It is important to distinguish spasmus nutans, a completely benign and self-restricting disease, from potentially severe conditions which may appear with similar symptoms. It should be expected that this clinical condition will become more frequent in view of the considerable increase in the size of the non-EEC population.

Combined Modality Therapy↗
PubMedDate not supplied

[Malformations of the midline. A case-control study].

Defects of the middle line are an heterogeneous group of congenital malformations due to commune pathogenetic mechanisms. We have made a case-control study about 150 newborns, who have at least 1 defect of the middle line. Results prove an excess of males between the cases, due mostly to hypospadias. We haven't found families with defects of the middle line with x-linked manner of hereditary transmission. We haven't found any particular risk present in cases and not in controls. We haven't found any case with 2 or more middle line defects.

Case-Control Studies↗