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Biomedical subjects

T Gierek

Publications and source records attributed to T Gierek.

At least 55 records · Page 3Linked to original sources
PubMed1993

[Anatomical and functional results of middle ear reconstruction with tympano-ossicular allografts].

Twenty five patients with severely damaged middle ears underwent reconstructive surgery with using total tympano-ossicular allografts. Two years long follow-up showed average air-bone gap about 20 dB or better in 44% of patients. Materials and methods used for reconstruction in two groups (part I and II) were compared, basing on anatomical and functional results. In patients with total perforation and lack of malleus, reconstruction with the tympanic membrane allograft attached to the malleus handle and shaped incus columella revealed long-term hearing results improvement (63.6% closure of air-bone gap within 20 dB) better than in similar patients with a total tympano-ossicular allograft (44% closure of the air-bone gap within 20 dB) during 2 years long follow-up.

Adult↗
PubMed1992

[Qualitative determination of chemical compounds in the tissue of laryngeal cancer by x-ray microanalysis].

The authors presented the results of chemical compounds in the laryngeal cancer tissue in 20 patients with clinically and histologically confirmed plano-epithelial carcinoma using own modification of x-ray microanalysis method. Comparison between the healthy and neoplasmatic tissue showed as follows: 1) both healthy and neoplasmatic tissue showed the presence of Cd, Zn, Fe, Mn, Mg and Si, P, S, Cl, K, Ca, Ti; 2) the neoplasmatic tissue showed the presence of Pb whereas it was not observed in the healthy tissue; 3) both Pb and Cl were irregularly concentrated in the neoplasmatic tissue while in the healthy tissue showed regular concentration. The authors discuss some methodological aspects and try to interpret the obtained data in the view of toxic, mutagenous and carcinogenous role of the Pb.

Adult↗
PubMed1991

The trial of quantitative determination of the lead, chlorine, and sulfur content in the peripheral blood lymphocytes from patients with cancer of the larynx using the X-ray microanalysis method.

Using own modification of X-ray microanalysis method the authors evaluated the lead, chlorine, and sulfur content in the peripheral blood lymphocytes in 20 patients with laryngeal carcinoma in comparison with 20 healthy subjects of the control group. In patients with advanced clinical stages of that carcinoma the elevated lead and chlorine content has been stated in above cells whereas that of sulfur was decreased. According to the authors' opinion above changes reflect functional disturbances of lymphocytes in the patient with laryngeal carcinoma related to the decreased detoxicative properties, the intracellular electrolyte imbalance, and the enzymatic machinery alterations within that cells.

Adult↗
PubMed1990

[Pleomorphic adenoma of atypical localization].

The authors described 4 cases of multiform adenomata located in other than parotid gland sites. The diagnostic difficulties were stressed as well as the necessity of the histologic verification.

Adenoma↗
PubMed1989

[Superficial structure of lymphocytes from peripheral blood in patients with laryngeal cancer examined by scanning electron microscopy].

In 20 laryngeal cancer patients and in 20 normals 1927 and 1950 respectively the blood lymphocytes were examined by use of scan microscopy. The great differences were disclosed between the patients and normals. It was pointed out the considerable differences between patients and normals in the number of lymphocytes with plain surface (lymphocytes "G") in opposition to the intermediary and ciliated lymphocytes (differences statistically significant). In laryngeal cancer patients there were the significantly lower number of lymphocytes with ciliated surface (lymphocytes "Sz"). In the patient group there were the considerable differences in superficial structure of lymphocytes, probably as a response to cancer disease.

Adult↗
PubMed1989

[Tarflen-metal prosthesis in the surgical treatment of otosclerosis].

The authors described the prosthesis for otosclerosis surgery. It is made by plastic material connected with the tantalum+ or platinum wire. The mode of prosthesis adaptation and taking into the place was described. The prosthesis was devised and produced by Instytut Przemysłu Tworzyw i Farb Gliwice (Poland).

Humans↗
PubMed1989

Zinc, vitamins A and E, and retinol-binding protein in sera of patients with cancer of the larynx.

Serum vitamin A concentrations were measured in 22 patients with laryngeal cancer and found to be significantly lower than those of patients of similar age with either nonmalignant laryngeal or other than laryngeal diseases. The levels of vitamin A in the patients with laryngeal cancer, but not in the controls, significantly correlated with serum concentrations of retinol-binding protein (RBP) and zinc. It is suggested that low levels of zinc might reduce the synthesis of RBP and thus reduce the mobilization of vitamin A from the liver stores.

Aged↗
PubMed1988

The surface structure of peripheral blood lymphocytes from patients with laryngeal carcinoma evaluated by scanning electron microscopy.

Using the scanning electron microscopic technique the surface structure of the peripheral blood lymphocytes has been studied in 20 men aged 46 to 62 years with the laryngeal carcinoma diagnosed clinically and histopathologically. The control group consisted of 20 healthy men aged 39 to 58 years. According to the international classification 15 of 20 patients studied showed the T3N0M0 stage of the disease and other five the T4N0M0 stage respectively. The peripheral blood lymphocytes of the patients showed significantly greater variability of the surface structure as compared with the controls. The characteristic pattern of the lymphocytes in patients with cancer of the larynx was quantitative increase in numbers of lymphocytes having smooth surface deprived of microvilli and significant decrease of cells exhibiting numerous surface microvilli; these cells may correspond to the T and the B cell series, respectively. Moreover, the patients showed significant, approximately threefold increase in number of lymphocytes having the intermediate surface morphology between above mentioned two basic lymphocyte topographical types. According to the authors opinion above differences between the lymphocytes of patients with cancer of the larynx and those from healthy subjects are associated with the antitumor response of the lymphocytes.

Adult↗
PubMed1987

Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.

Lymphocytes from patients with cancer of the larynx have been characterized by the activity of two enzymes involved in purine metabolism--adenosine deaminase and purine nucleoside phosphorylase. It has been shown that purine nucleoside phosphorylase activity was 1.5-fold higher in lymphocytes of patients in comparison with a group of healthy individuals. Adenosine deaminase activity in lymphocytes was elevated three to four-fold. The authors suggest that especially the estimation of adenosine deaminase activity in lymphocytes would be a useful laboratory test in the study of immune responsiveness of patients with cancer of the larynx.

Adenosine Deaminase↗