Spinal cord injuries.
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Emergency Medical Services↗
Biomedical subjects
T Glick
Publications and source records attributed to T Glick.
Spreading the word about SCI nursing.
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Humans↗
A prospective study of fever and bacteremia after flexible fiberoptic bronchoscopy in children.
STUDY OBJECTIVES: To assess the incidence of fever and bacteremia after fiberoptic bronchoscopy in immunocompetent children. DESIGN: Prospective study. PATIENTS: Immunocompetent children undergoing fiberoptic bronchoscopy between January 1997 and June 1998. MEASUREMENTS AND RESULTS: Ninety-one children were included in the study. Forty-four children (48%) developed fever within 24 h following bronchoscopy. Bacteremia was not detected in any of the cases at the time of the fever. Children who developed fever were younger than those who remained afebrile (mean age, 2.4 +/- 3.6 years vs 4.2 +/- 3.7 years; p = 0.025). In the fever group, 66% of the bronchoscopies were considered abnormal, compared to 45% in the nonfever group (p = 0.04). Of the fever group, 40.5% of BAL fluid cultures had significant bacterial growth, significantly higher compared to the nonfever group (13.2%; p = 0.006). Of the 80 patients in whom BAL was performed, fever occurred in 52.5% compared to only 18.2% in those who did not have BAL (p = 0.03). BAL fluid content of cell count, lipid-laden macrophages, and interleukin-8 were not significantly different in both groups. In a logistic regression analysis, the significant predictors for developing fever were positive bacterial culture (relative risk, 5.1; 95% confidence interval, 1.6 to 16.4; p = 0.007) and abnormal bronchoscopic findings (relative risk, 3.1, 95% confidence interval, 1.2 to 8.3; p = 0.02). When age < 2 years was included in the model, this factor became highly significant (relative risk, 5.01; 95% confidence interval, 1.83 to 13.75; p < 0.002). CONCLUSIONS: Fever following fiberoptic bronchoscopy is a common event in immunocompetent children and is not associated with bacteremia. Risks to develop this complication are age < 2 years, positive bacterial cultures in BAL fluid, and abnormal bronchoscopic findings.
Bacteremia↗
Fine-needle aspiration of nodular hidradenoma: a case report.
A case of nodular hidradenoma presenting on the forearm of a 36 year old woman is reported. The diagnosis was made on fine-needle aspiration biopsy (FNAB). The cytologic features of the lesion are described. This is the first case to be diagnosed cytologically.
Adenoma, Sweat Gland↗
Sweat gland carcinoma diagnosed by fine needle aspiration (FNA).
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Adenocarcinoma, Mucinous↗
Merkel cell carcinoma diagnosed by fine-needle aspiration.
Merkel cell carcinoma is a relatively rare neoplasm of the skin. The present study describes three cases of Merkel cell carcinoma diagnosed by fine-needle aspiration cytology and reviews their histologic, cytologic, and ultrastructural features. The advantages of using fine-needle aspiration to diagnose Merkel cell carcinoma (and other cutaneous neoplasms) are emphasized.
Aged↗
Assessment of testicular spermatozoa morphology by image analysis.
OBJECTIVE: We objectively evaluated the testicular sperm cell morphology. METHODS: The spermatozoa head morphology was evaluated by image analysis as presented on testicular fine-needle aspiration cytology smears. RESULTS: 2,356 spermatozoa heads were classified into six groups, according to different morphology parameters. CONCLUSIONS: This objective method of morphologic assessment of testicular spermatozoa provides an important tool for the evaluation of testicular spermatozoa and can serve as a guide for therapy in male infertility.
Biopsy, Needle↗
Sclerosing haemangioma of lung mimicking carcinoma diagnosed by fine needle aspiration (FNA) cytology.
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Adenocarcinoma, Clear Cell↗
Chondroid syringoma diagnosed by fine-needle aspiration: a case report.
We describe a case of an 82-yr-old woman presenting with a thyroid nodule and axillary mass thought to be a metastasis. Fine-needle aspiration (FNA) revealed the axillary nodule to be a chondroid syringoma. We report here the cytologic features of chondroid syringoma and recommend the use of FNA in the evaluation of cutaneous and subcutaneous lesions in general.
Adenoma, Pleomorphic↗
Testicular fine needle aspiration as a diagnostic method.
We believe testicular FNA is a reliable, simple, and accurate method for the assessment of testicular pathology and can replace the biopsy. Only when insufficient conclusions may be drawn from the cytologic smears obtained is open biopsy indicated.
Adult↗
Studies on the pathophysiology of encephalopathy in Reye's syndrome; Hyperammonemia in Reye's syndrome.
The initial acid-base status of eight survivors of Reye's syndrome was characterized by acute respiratory alkalosis (Pco2=32 mm Hg; Hco3-=22.0 mEq/liter) while that of eight children who died was associated with metabolic acidosis as well (HCO3-=10.0 mEg/liter). Arterial-internal jugular venous ammonia concentration differences on day 1 (299 mg/100 ml) and day 2 (90 mg/100 ml) reflected cerebral uptake of ammonia while those on days 3 and 4 (-43 and -55 mg/100 ml) demonstrated cerebral release. Arterial blood hyperammonemia can be detoxified safely in the brain as long as the levels do not exceed approximately 300mug/100 ml. Beyond that level lactic acidosis is observed, particularly in cerebral venous drainage. Arterial blood hyperammonemia was also related to the extent of alveolar hyperventilation. These findings are very similar to those seen in experimental hyperammonemia and support the concept that neurotoxicity in children with Reye's syndrome is at least partly due to impaired oxidative metabolism secondary to hyperammonemia.
Acid-Base Imbalance↗
Use of CD34 and factor VIII to diagnose hepatocellular carcinoma on fine needle aspirates.
OBJECTIVE: The immunohistochemical staining patterns characteristic of hepatocellular carcinoma (HCC) using CD34 and factor VIII antibodies were compared with those of other hepatic lesions to determine if these stainings can be used as a diagnostic criterion. STUDY DESIGN: We reviewed 44 fine needle aspirates from the liver to evaluate the immunoperoxidase staining patterns on cell block preparations using CD34 and factor VIII and to determine whether this could distinguish HCC from the other lesions. These included HCC (14 cases), metastatic tumor (14 cases) and nonneoplastic liver lesions (16 cases). RESULTS: This retrospective study showed that in the nine documented cases of HCC, staining for CD34 and/or factor VIII was positive. The pattern of staining was either peripheral, around small clusters of tumor cells, or linear, diffuse and sinusoidal. In all the documented cases (27) of metastatic carcinoma and nonneoplastic lesions staining for CD34 and factor VIII was negative. In addition, there were eight problematic cases. In 7 cases the cytologic diagnosis on Papanicolaou-stained smears was inconclusive about HCC or metastatic carcinoma. CD34 and factor VIII confirmed the final diagnosis on the cell blocks. Based on this staining, 4 were HCC, 2 were metastatic carcinoma and 1 was equivocal, most probably HCC. In one case the differential diagnosis between well-differentiated HCC and a nonneoplastic liver lesion could not be made on cytologic smears, and here, also, CD34 and factor VIII aided in the correct diagnosis of a nonneoplastic liver lesion. CONCLUSION: We suggest immunoperoxidase staining with CD34 and factor VIII be performed on the cell block sections from FNAs in any problematic hepatic case.
Antigens, CD34↗
The problematic interpretation of foamy cells in breast fine needle aspirates. A report of two cases.
BACKGROUND: Lipid-rich carcinoma and primary malignant fibrous histiocytoma (MFH) of the breast are rare tumors. Cytologically the presence of cells with foamy cytoplasm can cause diagnostic difficulties in both tumors. CASES: Fine needle aspiration was performed on two females with breast masses. The lipid-rich carcinoma showed cells with fine, variably sized vacuoles in the cytoplasm. The MFH smears showed large, histiocytelike cells with foamy cytoplasm, both mononucleated and multinucleated. CONCLUSION: When presented with cytologic smears showing foamy cells, in addition to the nature of the nucleus one must pay attention to the size and character of the cytoplasmic vacuoles to differentiate between sarcoma versus carcinoma.
Adult↗
Necrosis of parotid pleomorphic adenoma following fine needle aspiration. A case report.
Fine needle aspiration of parotid tumors is used worldwide and usually is well tolerated by the patient, with no complications. We report a case of pleomorphic adenoma diagnosed by fine needle aspiration that underwent necrosis following the aspiration procedure.
Adenoma, Pleomorphic↗
Fine needle aspiration of the testis and correlation with testicular open biopsy.
The diagnostic value of cytologic examination of aspiration biopsy smears was compared with that of histologic examination of surgically removed biopsy specimens from 54 testes in 32 men with oligoazoospermia. In 47 testes (87.1%) a good correlation was found between the results of the two methods: 20 cases had normal testicular morphology, 10 cases had spermatogenic arrest, and 17 had only Sertoli cells. In the remaining seven cases there was a paucity of cells, not permitting a cytologic diagnosis. FNA of the testis is a reliable and simple method of evaluating male infertility.
Adult↗
The use of epididymal fine-needle aspiration for the diagnosis of male genital tract obstruction.
Epididymal fine-needle aspirations (EFNA) were performed on 29 epididymides of 17 infertile, azoospermic men in whom testicular cytology revealed adequate spermatogenesis. Sonograms confirmed the presence of all the excretory male organs. EFNA was performed to diagnose and locate the site of genital tract occlusion. The presence of cuboidal epithelial cells in the aspirate was the sole indication that epididymal content was aspirated. In 10 (34%) of the 29 aspirates there were only cuboidal epithelial cells and no spermatozoa, indicating proximal occlusion in the rete testis, in the canaliculi efferentes or in the most proximal segment of the epididymis itself. Occlusion in the distal segment of the epididymis or in the vas deferens was diagnosed in 13 epididymal aspirates (45%) which contained both cuboidal cells and spermatozoa. From 6 epididymides (21%) no conclusion could be reached because of failed aspirations. There are a variety of treatment modalities available for male genital tract obstruction, such as reconstructive surgery or assisted reproductive technology using sperm aspiration technique. The success rate of treatment is mainly dependent on the site of obstruction. Since vasography has its own limitations and hazards, diagnostic EFNA should be performed before treatment in men in whom genital obstruction is suspected.
Biopsy, Needle↗