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Biomedical subjects

T Grumme

Publications and source records attributed to T Grumme.

At least 19 recordsLinked to original sources
PubMed1979

[Trauma inflicted on a baby by shaking (author's transl)].

In a baby aged 8 months the forensic post-mortem revealed injuries to the parasagittal pontine veins without visible evidence of traumatic violence. The mother later admitted to having grabbed the baby laterally by the chest and shaken it. This had resulted in an angular acceleration of the head about a transversal axis and, by the lag of the brain due to its inertia, in the fatal vascular lesions mentioned. The twin child admitted to hospital with comparable signs rapidly developed via an acute hygroma a generalized cerebral atrophy such as is actually to be expected in senescence only.

Autopsy↗
PubMed1979

[The kinetics of contrast media in cerebral tumours (author's transl)].

The increase in density of cerebral tumours following intravenous injection of contrast media was measured by computer tomography and was evaluated quantitatively. The density increase of 158 tumours five minute after injection was between 0 and 29 CT units. There are considerable variations in density increase of various types of tumour, but the scatter is so wide as to preclude a diagnosis of tumour type. In 75 tumours repeated measurement of contrast changes were carried out for two hours following the injection. Again the variation differs with different types of tumour, but is not characteristic enough for exact clinical diagnosis. In 26 patients contrast concentrations were measured in the tumour and the blood and a pharmaco-kinetic compartmental analysis was carried out. In some tumours contrast changes can be explained by a single compartment model, whereas in others a two compartment model is necessary. Certain conclusions regarding the mechanism of contrast uptake can be reached.

Absorptiometry, Photon↗
PubMed1979

[Fracture of skull-comparative study of conventional and computer-assisted roentgenological examination (author's transl)].

Using a skull like phantome imaging characteristics of conventional x-ray technique and computerized tomography are compared. The contrast transfer function of x-ray films proofs to be superior, whichis due to overrange artefacts found in computerized tomography. Only 8 out of 50 skull fractures diagnosed by plain film technique were identified on computer-tomograms. Even though CT technique is excellent for the detection of intracranial lesions, fractures are more easily seen on conventional films. This is especially important for analysing size and site of impression fractures.

Humans↗
PubMed1978

CT of the base of the skull.

A systematic study of the structures of the base of the skull was performed with CT. The findings in 141 pathological cases are described. The value and some limitations of this kind of investigation are described and discussed. A comparison with conventional tomography is made.

Brain↗
PubMed1978

The diagnostic value of CT for radiotherapy of cerebral tumors.

The paper deals with CT followup studies on 73 patients with cerebral tumors who received radiotherapy. The value of CT for the indication of radiotherapy, for followup therapy and for the demonstration of therapeutic success are discussed. Since the cerebral tumors become visualized by means of CT in their entire extent and can be differentiated from perifocal edema, the question arises whether radiotherapy should consist of higher doses in the future. It is also suggested that the "clinical malignancy" may be used to compare the behavior of cerebral tumors when there is no exact histological classification. The possible histopathological effects of radiotherapy (edema, necrosis) and their demonstration by CT are discussed.

Adult↗
PubMed1978

[The diagnostic value of CT and angiography in cerebral tumors (author's transl)].

In a cooperative study the examination results of CT and angiography of 756 patients with verified supratentorial tumors were compared. CT displayed the higher diagnostic accuracy. Temporobasal tumors cause diagnostic problems for both examination methods. The value of arteriography is still unquestioned because using this examination method the differential diagnosis of mass lesions can be considered largely secured.

Adenoma↗
PubMed1978

Axial transverse computerized tomography in 73 glioblastomas.

Among 2,600 patients, examined by computerized tomography, 404 had brain tumours, which were gliomas in 150 cases. There were 73 glioblastomas. Examination was performed according to Ambrose's method using an intravenous injection of 1 ml 60% contrast medium per kg body weight. Thus 98% of all gliomas could be demonstrated. Glioblastomas are shown in three different forms: an annular type (55%), a nodular type (18%), and a combined type (27%). Perifocal oedema is found in 88% of glioblastomas. The oedema most frequently belongs to grade II or III. Differentialdiagnosis of gliomas, abscess, metastases and other tumours with central necrosis are discussed.

Astrocytoma↗
PubMed1978

[Computerized tomography in head injuries (author's transl)].

Computerized tomography permits the registration of minimal density differences of cerebral tissue. The information obtained by this method is comparable to gross neuropathology. Demonstration of intracranial bleeding and other posttraumatic complications does not present any serious problem. Most of all, it permits for the first time to demonstrate directly parenchymatous lesions of cerebral tissue after a head injury. The treatment nowadays can depend largely on the results gained by computerized tomography. So the care of the patient will be influenced largely by the demonstration of lesions affecting the survival of the patient.

Brain Abscess↗
PubMed1977

Computed tomography in the diagnosis and differential diagnosis of glioblastomas. A qualitative study of 295 cases.

The CT patterns of 295 glioblastomas examined with pre- and postcontrast scans using an EMI scanner Mark I (Matrix 160/160) have been reviewed and compared with the CT appearances of other brain tumors, metastases and abscesses. There is a great variety of CT patterns with glioblastomas. However, a garland-shaped CT appearance, representing a subgroup of ring-shaped lesions, seems to be most typical for glioblastomas since it was observed in 19% of ring-shaped glioblastomas but in only one out of 172 metastases and in no case of an astrocytoma grade II or an abscess in our series. The initial CT diagnosis, based on the CT finding, the patient's history and the clinical data, was correct in 69.8% of the glioblastomas, 41 recurrent glioblastomas included. In 12% of the cases the presence of a glioblastoma was within differential diagnosis. These results lead to the conclusion that in many cases additional diagnostic methods, such as serial scintigraphy and/or cerebral angiography, are required for a reliable differential diagnosis.

Astrocytoma↗
PubMed1977

[A computer-tomographical examination of cranial bullet wounds (author's transl)].

The report covers the computer-tomographical examination of six patients with acute cranial bullet injuries and fifteen patients suffering from the sequels of such injuries. The diagnostic and prognostic significance of this method of examination in the case of acute injuries is described. The extent of cerebral defects in the case of sequels can be documented during this process by means of x-ray. The computer-tomography therefore offers an objective basis for the assessment of this type of sequela.

Adolescent↗