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Biomedical subjects

T Grzelec

Publications and source records attributed to T Grzelec.

11 recordsLinked to original sources
PubMed1990

[Risk of coronary heart disease in metallurgy employees in light of prospective examinations].

The group of physical workers of metallurgic plant (average period of employment was 12.4 +/- 6.4 years) consisting of 1100 men aged from 20 to 59 years, was underwent double medical examination in 5 years interval in standard clinical conditions. The 8 risk factors of coronary heart disease (CHD): aged, sex, family history, systolic blood pressure, cholesterol blood concentration, body weight, cigarette smoking and professional physical activity were analysed. Each factor was graded from "0" to "8" points. To evaluate individual risk of CHD all points were summed to give the total score. It was found, in both examinations, that most of examined persons showed an average risk of CHD. The second examination (5 years after the first) demonstrated an increase of percent the workers with higher risk of CHD. The smoking habit and overweight were the most important among risk factors in the population studied.

Adult↗
PubMed1990

[Risk factors of coronary heart disease in various occupational groups. I. Analysis of risk factor incidence].

The subjects of investigation in a standard clinical conditions were 4 groups of workers: blast furnace workers (n = 121), operators (n = 131), persons from managic staff (n = 73) and monks (n = 81). In all subjects 8 factors enhancing ischemic heart disease were estimated: treating family history, habit of smoking, male sex, blood hypertension, obesity, increased cholesterol concentration in blood serum and small physical activity. It was found that investigated groups were significantly different as to frequency of occurrence of ischemic heart disease risk factors.

Adult↗
PubMed1977

[Secretory function of the stomach in workers employed at petroleum prospecting].

A group of 100 petroleum miners exposed to noise and vibration at intensities surpassing admissible standards, were subjected to a study. In the subjects basic and maximum posthistamine gastric secretion was evaluated, then stomach and duodenum were examined radiologically. Peptic ulcer was diagnosed in 10% examined, i.e., a percentage resembling the highest home data. It was found that mean values of maximum posthistamine secretion decreased with age. No influence of length of employment or accompanying chronic effect of noise, vibration and bad living conditions upon gastric secretion values (BAO and MAO), was found. Neither found one differences in the rate of occurrence of peptic ulcer and gastric secretion disturbances between the group of persons with diagnosed occupational diseases (vibration disease and occupational hearing impairment) and the group of the remaining subjects. Instead a significantly negative correlation between the age of workers with occupational hearing impairment and BAO and MAO values was observed.

Duodenum↗
PubMed1973

Inhibition by secretin of the gastric acid responses to meals and to pentagastrin in duodenal ulcer patients.

The inhibitory effects of intravenous secretion on the gastric acid responses to a meal and to pentagastrin were studied in seven duodenal ulcer patients.A test meal of 10% peptone adjusted to pH 5.0 was introduced into the stomach and the Fordtran and Walsh method was used to measure the gastric acid output by monitoring the rate at which a solution of 0.3 M sodium bicarbonate had to be added to keep the pH of the gastric content constant at the value of 5.0. A constant dose of secretin (1 U/kg-hr) significantly depressed the serum gastrin response to a meal and produced an inhibition of acid secretion by about 70% of the control level. Secretin inhibited the acid response induced by pentagastrin by about 60% and simultaneously provoked a pancreatic bicarbonate output sufficient to neutralize about 60% of the gastric acid output to pentagastrin. We conclude that secretin is a strong inhibitor of gastric secretion in duodenal ulcer patients induced by a meal and by pentagastrin.

Adult↗