Biomedical subjects
Publications and source records attributed to T Gualtierotti.
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The technique of single unit recording from body systems generating electrical pulses coherent with their basic function (CNS, muscles, sense organs) has been proved feasible during the OFO A orbital flight, an automatic physiological experiment. All microelectrode implants survived the lift off of a Scout vehicle. The far-reaching impact of such a technique in biological space research and in the laboratory is discussed. The results of recording 155 hours of orbital flight of pulses from the nerve fibres of four vestibular gravity sensors in two bull frogs indicate that the vestibular organ adjusts to zero g. As all the other biological changes observed during orbit are due to lack of exercise, it is concluded that artificial gravity might not be necessary during prolonged space missions or on low gravity celestial bodies.
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In the frog skin Na+ transport has been studied using 24Na+ and the short circuit technique, with or without a 650 gauss steady magnetic field. The magnetic field reduced the influx of sodium by 10-30%. In short circuit experiments the current appeared to be altered within 1 second of increasing the field. Such effect seems to be due to a block in active transport of sodium since the addition of 3 mM ouabain to the inside solution prevented the change.
In the pigeon vestibular responses from threshold to saturation will be compared in laboratory and in a satellite zero gravity. It is expected that following the Weber-Flechner law sensitivity in zero gravity conditions will be much higher. The experiment in orbit and the necessary equipment are described.