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Biomedical subjects

T H FLEWETT

Publications and source records attributed to T H FLEWETT.

At least 19 recordsLinked to original sources
PubMed1963

'Hand, foot, and mouth disease' associated with Coxsackie A5 virus.

Seven cases are described of highly infectious disease characterized by vesicular eruptions in the mouth and on the hands and feet. In previous outbreaks described in the literature Coxsackie type A16 virus was isolated but from these cases, similar clinically, Coxsackie type A5 virus was isolated.

Coxsackievirus Infections↗
PubMed1963

A case of vaccinia necrosum (or progressive vaccinia), with severe hypogammaglobulinaemia, treated with n-methyl isatin beta-thiosemicarbazone (33T57).

A fatal case of vaccinia necrosum treated with antivaccinial gamma globulin and N-methyl isatin beta-thiosemicarbazone (33T57) is described. Histological abnormalities found at necropsy included intranuclear as well as cytoplasmic inclusion bodies, absence of lymphoid germinal centres, grey hepatization, and bronchiolar epithelial hyperplasia. Virus titres were highest in the original skin lesion; virus was also found in the lymph node draining it and in the kidney and the brain. No toxic effects could be clearly attributed to the drug used in treatment.

Agammaglobulinemia↗
PubMed1961

Death of an infant in hyperthermia after vaccination.

Death following hyperpyrexia and coma of rapid onset nine days after vaccination of an infant is reported. Death appeared to be due to overwhelming vaccinial infection without encephalitis. Large amounts of virus was present in lung, spleen, bone marrow, and the vaccination site.

Death↗