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Biomedical subjects

T H Lesser

Publications and source records attributed to T H Lesser.

24 records · Page 2Linked to original sources

Efficacy of medical treatment as an adjunct to surgery in the treatment of secretory otitis media.

In a pilot controlled randomised trial of 38 children who had bilateral secretory otitis media, with effusion demonstrated at operation, we compared the efficacy of a six-week course of an oral decongestant--antihistamine combination and a mucolytic preparation with a control group in preventing the presence of middle-ear effusion six weeks after myringotomy and adenoidectomy. The mucolytic preparation decreased the presence of middle-ear effusion when compared to the decongestant-antihistamine combination and the control group (p = 0.06).

Adenoidectomy

Day case surgery in otolaryngology: a 10-year analysis.

This paper analyses the ENT day case surgery performed over the period May 1974 to May 1984 in Cardiff. The patients undergoing such surgery, the types of surgery, forms of anaesthesia, travelling considerations, seasonal variation and admission rate are examined. The problems of list organization, patient selection and attendance are examined in detail in a 12-month period from May 1981 to May 1982.

Adolescent

Pseudotumoral mycobacterial infection in the head and neck: a clinical study.

The clinical aspects of mycobacterial infection of the head and neck are considered as presenting in patients at a cancer hospital over the last 15 years. Some difficulties in diagnosis with respect to the evolution of tuberculosis in this region are discussed. A total of 32 patients with evidence of infection were identified. Twenty-six of these with cervical lymphadenopathy are considered as a group; their clinical features and diagnosis are summarized and a note made of the recent change in the macroscopic quality of the nodes removed. Six cases are given particular attention: two with laryngeal tuberculosis, two with nasal or adenoidal infection and two with atypical mycobacterial infection diagnosed on clinical grounds.

Adolescent

Implantable hearing aids: changes in the auditory-evoked potential of the monkey in response to increased loading of the stapes.

This study examines the effects on the hearing response in the monkey resulting from an increasing load on the stapes exerted by an implantable middle ear transducer. The transducer was placed on the distal end portion of the long process of the incus in monkeys and progressively advanced in small increments in the direction of the long axis of the stapes. Auditory-evoked potentials were recorded to assess the hearing response induced by the vibration of the transducer at each point. A decrease in response equivalent to a change in stimulus sound pressure level of approximately 20 dB occurred as the load on the stapes increased. Frequency response may also change. Our results imply that, to achieve maximum efficiency, the load placed on the ossicles by a vibrating transducer must be minimized.

Animals

Totally implantable hearing aids: the effects of skin thickness on microphone function.

With the advent of totally implantable hearing aids, the question of the impact of the choice of implantation site on microphone function has yet to be fully addressed. We investigated the effects of skin thickness on microphone function over a 2-week period in a porcine model. Sound attenuation was found to be directly proportional to skin thickness within the range of 0.5 to 3.0 mm. A decrease in resonant frequency of 500 Hz was noted after implantation under a skin thickness of 3.0 mm. The general shape of the frequency response curves was maintained across all thicknesses tested. Attenuation (dB loss) across the range of 500 to 8,000 Hz appeared to be linear over the various skin thicknesses measured, with a regression coefficient (r = .99 at 1 kHz and r = .99 at 3 kHz). To minimize attenuation and exploit the sound-collecting qualities of the external ear, the deep meatal skin appears to be a favorable position for implantation.

Animals