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Biomedical subjects

T Harder

Publications and source records attributed to T Harder.

At least 127 records · Page 7Linked to original sources
PubMed1987

[Follow-up study in chronic polyarthritis as represented in roentgen image].

Thirty-one patients with chronic polyarthritis under medical treatment had x-rays of their hands performed at the beginning of the illness and after seven years, on average. The findings were compared with clinical and biochemical data. Despite treatment, there was marked progression in the periarticular destructive changes, although the clinical features had improved. The extent of periarticular destruction was significantly greater amongst seropositive than amongst seronegative patients, both at the beginning and the end of the study, but there was no significant difference in the rate at which this progressed. It was not possible to demonstrate a statistically significant correlation between the radiological appearance of the joints and the clinical and laboratory findings.

Adult↗
PubMed1987

[MR tomography of Kallmann's syndrome].

MR tomography is the only imaging method that can demonstrate atrophy of the olfactory lobe of the brain in olfacto-genital dysplasia (Kallmann's syndrome). The MRT findings in five patients with Kallmann's syndrome are described. The MRT criterion for the presence of Kallmann's syndrome appears to be an interruption or total absence of the olfactory sulcus.

Adult↗
PubMed1987

[CT findings in ruptured abdominal aortic aneurysms].

In nine patients with ruptured aneurysms of the abdominal aorta and in one patient with a ruptured aneurysm of a common iliac artery who also had an abdominal aortic aneurysm, CT was performed. Three of the nine patients were also examined by sonography. CT proved to be the method of choice in the diagnosis of ruptured abdominal aortic aneurysms. The most important CT signs are: demonstration of an aortic aneurysm; haematoma usually unilateral and retroperitoneal; ventral or ventro-lateral displacement of a kidney; enlargement of the psoas, which may be indistinguishable from the haematoma, possibly with direct penetration of the psoas fascia; indistinct margin of the aortic wall at the rupture site.

Aged↗
PubMed1987

[MR tomography following kidney transplantation].

The results obtained by MR tomography in 30 patients after renal grafting are compared with the clinical and histological data in respect of corticomedullary contrast (CMC). In 22 patients with regular functioning of the transplant the CMC was normal at 19.4%. Eight MR examinations yielded a clearly reduced CMC below 14%. In 7 of these 8 patients it was possible to prove histologically the existence of an acute tubular necrosis or of a transplant rejection. Noninvasive MR tomography yielded an early indication for treating the acute renal transplant rejection without being able to differentiate between such a rejection and acute renal failure.

Adult↗
PubMed1987

[MR tomography in the control of chemonucleolytic therapy].

MR tomography can be used for the diagnosis of lumbar disc prolapse and provide information concerning the indications and the follow-up of injection treatment with chymopapain. It is able to distinguish various parts of the disc from their varying signal intensity. Examination of 26 patients showed the effect of chymopapain on intradiscal fluid shift based on shifts in signal intensity. The use of T2-weighted gradient echo sequences over a period of seven to ten minutes is sufficient to show significant changes in the disc following chemonucleolysis.

Female↗
PubMed1987

[MR tomography in lymphatic and leukemic bone marrow infiltrations. A comparison with scintigraphy and conventional x-ray diagnosis].

MR is the only noninvasive procedure that can demonstrate changes in the medullary space. If it is combined with bone marrow scintigraphy and conventional x-ray film diagnostics, it can yield a comprehensive diagnosis of bone marrow infiltrations in the regions of the pelvis, thighs and lumbar vertebral column in leukaemia or malignant lymphomas. The T1 relaxation times of the malignant infiltrations are enhanced compared with normal fatty marrow. MR tomography of the bone marrow is particularly suitable for determining the therapy or follow-up control of a malignant systemic disease.

Bone Marrow↗
PubMed1987

[Modified T2-weighted gradient echo sequence for MR tomography of the CNS].

We introduced a modification of T2-weighted rapid sequence imaging which combines the advantages of conventional spin echo sequences with those of gradient echo sequences. It provides a method which is suitable for clinical routine use. Using a 1.5 Tesla field, one obtains good image quality with contrast comparable to spin echo sequences, while reducing the time taken to examine the brain to one-half and that of the spine to one-third. Our experience in 54 patients is described.

Brain↗
PubMed1987

[Therapeutic results in small-cell bronchial carcinoma after ACO II chemotherapy and adjuvant radiation].

During the period from 1980 through 1984, 67 patients suffering from small-cell bronchial carcinomas were submitted to a complete ACO II treatment scheme combined with adjuvant irradiation. The complete remission rate was 12%, the partial remission rate 74%. Half of the patients with limited disease survived 12.3 months or more. The median survival time of patients with extensive disease was eight months. An irradiation of the tumor core had been found useful in cases where remote hematogenous metastases could not be demonstrated. It was shown that a prophylactic skull irradiation after the second chemotherapy series was applied too early, because persisting primary tumor residues formed late intracerebral metastases.

Adult↗
PubMed1986

[Digital subtraction angiography in traumatology].

The methods, indications and results of digital subtraction angiography in traumatology are presented, based on 56 examinations. The different use of intravenous or intraarterial DSA will be discussed with respect to expanding and localisation of traumatic vascular injury. DSA is recommended as the method of choice for follow-up after vascular reconstructive procedure.

Angiography↗
PubMed1986

[Digital subtraction angiography of the aorta].

The results of 300 digital subtraction angiographies of the thoracic and abdominal aorta are analysed. Following intraarterial injection of contrast, all examinations were of good quality. Following I-V DSA, two thoracic (1.8%) and two abdominal (1.2%) aortograms were non-diagnostic. Anomalies in the position of the aorta, dilatation (aneurysm) or stenoses (coarctations, arteriosclerosis, occlusions) could be diagnosed by I-V DSA. One I-A DSA was performed for aneurysm of the ascending aorta in order to evaluate function of the aortic valve and for demonstrating the coronary artery origins, and pre-operatively for an aortic dissection.

Aortic Dissection↗
PubMed1986

Aneurysmal hemorrhage of the kidney caused by angioleiomyoma.

A small angioleiomyoma consisting of proliferating smooth muscle cells and vessels caused macrohematuria in a 52-year-old female patient. The locally ill-defined tumor in the fatty tissue of the renal pelvis immured small arteries and veins as well as an interlobar artery, and caused damage to the vascular walls accompanied by the development of aneurysm, perforation and fistulation into the renal pelvis, by mechanisms open to various pathogenetic interpretations. Preoperative radiological diagnosis yielded a subcapsular hematoma, and showed more intense contrast medium staining of the upper renal pole. Dysontogenetic tumors are most frequently located in the renal cortex and are capable of locally destructive growth. They are usually well defined and of nodular structure. As, in our case, an exact diagnostic assessment of the process was lacking and both the location and growth pattern of the tumor were atypical, an organ-preserving resection was deemed unsuitable and nephrectomy was performed.

Aneurysm↗
PubMed1985

[Serial computed tomography. Value of densitometric measurements in the diagnosis of benign and malignant lesions of the liver, pancreas and kidney].

By means of serial computer tomography it is possible to show changes in normal and abnormal tissues in the liver, pancreas, and kidney with characteristic contrast kinetics. Diagnosis can be improved by evaluating intra-vascular parenchymal contrast within the first minute after an intravenous bolus injection. A tissue diagnosis is not possible in the majority of lesions in the liver, but can usually be made in lesions of the pancreas and kidneys.

Carcinoma, Renal Cell↗
PubMed1985

[Cavography in the digital subtraction technic].

Experience with 74 patients has shown that digital subtraction angiography is a suitable method for the demonstration of the vena cava. In 28 patients the examination was repeated by the conventional large film angiography procedure, but this added no significant information to help to solve the clinical problem. Electronic contrast enhancement permits lower concentrations of contrast to be used than for conventional techniques. Combined with a more selective use of films, this leads to a reduction in the cost of the examination.

Humans↗