Biomedical subjects

T Hefer

Publications and source records attributed to T Hefer.

22 records · Page 2Linked to original sources

PubMed1994

Highly invasive papillary thyroid carcinoma.

Papillary carcinoma is the most common malignant tumour of the thyroid gland, accounting for at least two-thirds of newly diagnosed carcinomas. This tumour may be occasionally multicentric in origin. It frequently spreads to regional lymph nodes in the neck and mediastinum, but uncommonly metastasizes outside these regions. Local invasion of this tumour to the upper airway or digestive tract structures is infrequent. However, when that occurs, it is a source of significant morbidity and mortality. In the last two years four patients suffering from invasive papillary carcinoma to the aerodigestive tract were treated in our department. A short case history of one of them is presented and current trends in management of the disease are reviewed.

Carcinoma, Papillary↗

PubMed1993

[Upper airway obstruction--a rare complication after anti-coagulant therapy].

A case of progressive, spontaneous, nontraumatic hemorrhage into the tonsil, soft palate, hypopharynx, and larynx in a patient receiving oral anticoagulants is presented. There was no evidence of bleeding into other parts of the body. The presenting symptoms of sore-throat, dysphagia and hoarseness were mild at the time of admission. However, the bleeding later caused upper airway obstruction and aspiration, and the clinical picture during hospitalization became dramatic and life-threatening. Physicians should be aware of such possible complications in anticoagulant-treated patients, and if a hematoma is found in the pharynx or larynx the patient should be admitted for close observation and treatment. To the best of our knowledge this is the first reported case of spontaneous hemorrhage into the tonsil in a patient on oral anticoagulation.

Administration, Oral↗

PubMed1983

Pressured pattern or type A behavior in patients with peripheral arteriovascular disease: controlled retrospective exploratory study.

The question as to whether a specific behavior or type A pattern is limited to patients with coronary artery disease, or is found in atherosclerotic disease, in general, is explored. The interrelationship between a pattern of "pressured" behavior, assessed by open ended interviews, type A behavior, determined by the Bortner test, and peripheral atherosclerotic disease was investigated in a controlled retrospective study which compared three groups of 13 patients each: intermittent claudication (IC), intermittent claudication combined with coronary artery disease (CADIC) and a control group of patients without vascular disease (WVD). A pressured behavior pattern, assessed by interview, was found to be most prominent in the CADIC group, and least in the control group. The subjects with arteriovascular disease tended to exert more control over people compared to the WVD patients (Fisher's exact probability test, p = 0.05). The tendency to type A behavior, measured by means of the Bortner scale, also differentiated the three groups with CADIC scoring highest and WVD scoring lowest (analysis of variance, F = 3.944, p less than 0.05). IC patients present personality features of proneness to coronary disease. The pattern of "pressured" and type A behavior seem to correlate with the number of vascular areas involved in atherosclerotic disease.

Coronary Disease↗

PubMedDate not supplied

Hyoid bone syndrome and its treatment with nonsteroidal anti-inflammatory drugs.

PURPOSE: Nonspecific cervical pain is a common complaint in primary ear, nose, and throat clinic patients. In some cases, hyoid bone syndrome has been recognized as the cause of the complaint. Our study describes this common but unrecognized syndrome and suggests a treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), a method of treatment not previously reported for this syndrome. PATIENTS AND METHODS: Patients with suspected hyoid bone syndrome (38) were treated with oral NSAIDs and/or with an NSAID ointment for topical application. RESULTS: Symptomatic relief was obtained in 66% of our patients and in 71% of the patients treated by NSAID tablets. Symptomatic relief was obtained in 91% of the patients with symptom durations of less than 6 weeks. CONCLUSION: We recommend a course of NSAID therapy as the first method of treatment for this syndrome before treatment with invasive procedures, especially for patients with symptom durations of less than 6 weeks. Better recognition of the hyoid bone syndrome will result in a more effective treatment and will avoid an unnecessary investigation.

Anti-Inflammatory Agents, Non-Steroidal↗