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T Hein

Publications and source records attributed to T Hein.

4 recordsLinked to original sources
PubMed2000

[Projection of the number of multiple sclerosis patients in Germany].

For determining the prevalence of multiple sclerosis (MS) in Germany, the outcomes of several epidemiological studies are available. If these rates are transferred to Germany as a whole, figures result of 67,000 to 138,000 MS patients in all. The differing prevalence rates may be caused by various problems in finding patients, the epidemiological area, and different population structures. To avoid these difficulties, a new approach for calculating the number of patients with diagnosed MS was chosen based on representative samples taken from the groups of physicians involved in MS treatment. The disadvantage of this approach is that it does not allow any questioning of the diagnosis. Projecting the results in this way and their subsequent compilation--taking "double treatments" into consideration--showed a total of 122,000 patients with diagnosed multiple sclerosis in Germany. This figure corresponds to a prevalence rate of 149.1 per 100,000 inhabitants and is within the range found by Poser et al. [19]: 127 per 100,000 excluding the diagnostic category "possible multiple sclerosis" and 170 per 100,000 including it.

Data Interpretation, Statistical↗
PubMed1998

[Prostatic cancer in the Grand Duchy of Luxembourg. Role of PSA].

We reviewed the trends in prostate cancer incidence and mortality in Luxembourg between 1983 and 1995 to discuss the importance of total and free PSA in early detection. The study was performed on all the new cases recorded by the National Cancer Registry (Registre Morphologique des Tumeurs). Total and free PSA were measured with the automated Immulite System (DPC, Los Angeles) using a chemoluminescent immunometric assay. The performance of free-to-total serum PSA was analysed by a hospital based study of 113 patients (55 PC, 58 BPH). The age standardized incidence rate increased from 29.3/100,000 in 1983 to 71.5/100,000 in 1995. Mortality rates only changed slightly. The widespread use of PSA testing from 1988 on is probably the main cause of this incidental increase; however no major changes in the age-specific-incidence have been found suggesting the absence of a systematic screening policy by the PSA. The superiority of free-to-total serum PSA ratio in discriminating between cancer and benign condition was confirmed. Early health-conscious man over 50 should be proposed prostate cancer screening by digital rectal examination and PSA. However a systematic screening policy cannot been recommended since a benefit in survival after early treatment has not yet been proven.

Adult↗
PubMed1995

[Renal adenocarcinoma and radical nephrectomy].

74 cases of radical nephrectomy for adenocarcinoma are reported. The authors review the clinical aspects and the accuracy of imaging and insist on fortuitous detection of early stages by ultrasound. Survival is studied with regard to tumor stage, transfusion and cell type.

Adult↗