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Biomedical subjects

T Hurmuzache

Publications and source records attributed to T Hurmuzache.

At least 19 recordsLinked to original sources

[Effectiveness of repeated antibiotic or chemotherapeutic treatments on Shigella carrier states].

A group of 39 former dysentery patients, who continued to excrete Shigella bacteria after a first cure of antibiotics when full clinical recovery was obtained, were treated differentially under bacteriological control. The carrier state was still extent in 7% of the cases after three antibiotic or chemotherapeutical cures. No direct relation was found between the sensitivity of Shigella to chemotherapeutics and the level of the carrier state. Although treated already in the acute stage with adequate antibiotics, resistance to a second therapeutical attempt was recorded in a proportion of 33%. It is considered useless to repeat the antibiotic or chemotherapeutical cures in the treatment of convalescent carriers because of the low efficiency and the biological and economical disadvantages.

Adolescent

[Lyme disease].

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Anti-Bacterial Agents

[Bacterial liver abscess cured by nonsurgical treatment. Comments on 8 cases].

Eight cases (3 children aged 7-15 years and 5 adults aged 16-46 years) of hepatic abscess in whom a cure was obtained by medical therapy are presented. The abscess occurred during septicemia (2 cases), cutaneous staphylococcosis (2 cases) and pyocholecystitis (1 case). In 3 patients the abscess remained cryptogenic. The clinical diagnosis was confirmed by scintigraphy, ultrasonography and in one case by radiography with contrast substance in the abscess. The microorganisms, isolated in 3 patients from the abscess and in one patient from hemoculture, were S. aureus (3 cases) and gram negative bacilli (1 case). The systemic antibiotic therapy consisted in the administration of gentamicin and oxacillin or rifampicin in 4 cases and gentamicin and chloramphenicol or ampicillin and metronidazole in other 4 cases for an average interval of 39 days. The associated local therapy (3 cases) consisted in one or more punctures, followed by the injection of gentamicin.

Adolescent

[Nutritional immunity].

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Bacterial Infections