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Biomedical subjects

T I Avdiukhina

Publications and source records attributed to T I Avdiukhina.

18 recordsLinked to original sources

[Outbreak of giardiasis at a preschool children establishment in the town of Perm'].

In November 2000, an outbreak of Giardiasis intestinalis with aqueous transmission was recorded in one of the microdistricts of Perm. Thirty six children aged 1-7 years fell ill, 2 parasitic carriers were identified among the staff. The diagnosis was parasitologically verified in all children with clinical manifestations. Enzyme immunoassay was positive in 87.5% of the patients with the parasitologically verified diagnosis. The aqueous nature of the outbreak was confirmed by the detection of Lamblia cysts in the samples of water from the transfer network of the microdistrict in November 2000 and by the higher incidence of giardiasis among the microdistrict's residents since April 2000. Macmiror in age-specific doses was used to treat patients. The therapeutical efficiency of one course was 100%. If outbreaks of intestinal infections of unknown etiology occur, a parasitological survey should be made among patients and those who have contacted with them. Prolonged diarrhea was one of the major symptoms of giardiasis during an outbreak of this intestinal infection.

Animals↗

[False parasitic diseases].

The paper deals with the topical problem of false parasitic diseases (FPD) in patients with various organic (somatic and mental) disorders. A classification of groups of FPD patients is given according to their clinical and social signs. Examples of 6 cases of FPD observed by the authors and those published in the literature are presented. Simple and effective recommendations on the management of FPD patients are given.

Adult↗

[Treatment of giardia in children under current conditions: efficacy and choice of specific drug].

The formalin ester-enrichment test for giardiasis was used to examine 742 children aged under 14 years at children's clinical hospitals in the town of Perm in February to October 2000. All the children had symptoms of gastrointestinal lesions. Giardiasis was detected in 26.4% of the children; including 21% among 200 children aged 0-2 years, 26.6% among 297 children aged 3-6 years, 30.6% among 245 children aged 7-14 years. Various background abnormalities were revealed in 158 children, including 62 and 68 children aged 3-6 and 7-17 years, respectively. The background abnormality makes a clinical diagnosis of giardiasis difficult and lowers the efficiency of specific treatment. Macmiror and tiberal are the most effective in treating giardiasis in all age-group children. Tiberal is preferable for treating children without background abnormalities. Specific treatment for giardiasis should be combined with the use of probiotics and enzymes.

Adolescent↗

[The status and tasks of the training of parasitologists in the USSR].

Modern state of under- and postgraduate training of medical parasitologists is reviewed. Main tasks for the improvement of specialist training have been outlined, in particular due to the fact that the educational institutions will work on a self-accounting principle in the nearest future.

Certification↗

[How many patients with visceral toxocariasis in Russia?].

Based on the results of numerous seroepidemiological surveys of inhabitants in Russia using the Toxocara/IgG enzyme immune test system and supposing that extremely high antibody titers (1:6400 or higher) are an indicator of manifest visceral toxocariasis, the possible number of patients with this infection was estimated in the Russian Federation. The absolute number of the patients is roughly 550,000, the relative rate is 380 per 100,000 population. Children aged 0-9 years were shown to prevail among patients with visceral toxocariasis; among the children, boys are predominant. The paper also provides the percentage of seropositive individuals in various in various foci of Russia and its adjacent states (among the 21,233 inhabitants under study, the mean rate is 6.8% ranging from 0 to 21.5%). Groups at risk for Toxocara canis infection include veterinarians, automobile drivers and fitters, scavengers, among whom the number of seropositive individuals is substantially higher than that in the control group of inhabitants.

Adolescent↗

[The results of a serological examination of the population for toxoplasmosis and the estimated incidences of congenital toxoplasmosis in 2 foci in Uzbekistan].

Enzyme immunoassay was used in screening for toxoplasmosis of 500 residents of the town of Ghulistan and of 1074 residents of the town of Shavat in the Khorezm district of Uzbekistan. All the examinees were aged 15 to 40. The share of seropositive subjects in Ghulistan was 24.6%, that in Shavat 14.6%, the toxoplasmosis loimopotentials were 0.87 and 0.62%, respectively. The predicted parameters were as follows: new cases of toxoplasmosis among pregnant women were 4.9% in Ghulistan and 3.9% in Shavat, the incidence of congenital condition 1.7 and 1.3%, respectively, the incidence of manifest congenital toxoplasmosis 0.6 and 0.4%, respectively. The presence of a cat in the house was associated with higher share of seropositive subjects in the town of Shavat as against Ghulistan. An urban focus (Ghulistan) appeared more intensive as against a rural type focus (Shavat) at the expense of a higher intensity of the xenotropic route of the agent transmission.

Adolescent↗

[Dirofilariasis in the countries of the CIS: an analysis of the cases over the years 1915-1996].

A hundred and fourteen cases of subcutaneous dirofilariasis caused by Dirofilaria repens were described in the CIS in 1915-1996. The mean age of the patients was 38.4 years (from 3 to 70 years). Dirofilaria was found in the eye in 45.9% of cases, in the head and neck in 17.5%, in the arms and hands in 11.7%, in the legs in 8.1%, in the viscera in 2 cases, and in the genitalia in 2 cases, they being prevalent in the body's right part. The north boundary of local infection cases was in latitude 53-54 degrees North. The maximum cases were detected in January and June. Dirofilariasis clinically appeared as a migrating subcutaneous tumor occasionally complicated by secondary abscess. The tumor generally contained an immature female, an immature male was found in one case. The sole treatment was surgical helminthic excision. There was a trend of subcutaneous dirofilariasis cases to increase in the RF in the past decades.

Adolescent↗