Whether complex indices of ambient air pollution can be used for sanitary ranging of primary facilities of the district was studied. The indices were calculated by using single air samples. The impact of "zero samples" on the results of calculation of the significance of differences in the single concentrations of individual chemical air pollutants was examined. The average annual concentrations of pollutants were calculated on the basis of average daily maximum allowable concentrations and the a-coefficient recommended by M. A. Pinigin. The database contains 20,000 definitions of the most hazardous chemical pollutants in the ambient air. Significant and insignificant values of chemical pollutants in single ambient air samples may be used in calculating complex indices as the rate of result coincidence was 80%, the suitability of insignificant values for ranging was confirmed in 81.25% of cases.

Air Pollution↗

PubMedDate not supplied

[The radiographic image of hemorrhage in hemophilia].

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Adult↗

PubMedDate not supplied

[Determination and analysis of the primary structure of a genomic sequence adjacent to the 3'-end of the human tissue plasminogen activator gene].

Primary structure was determined for the recently cloned f1/BglII-fragment [19] containing 2102 b.p. of the human tissue plasminogen activator (tPA) gene 3' end and adjacent DNA region. Computer analysis has revealed an Alu-repeat 820 b.p. downstream the tPA gene; the sequence proved to have a considerable homology (86-88%) with the Alus from the 3'-untranslated regions (3'UTRs) of cytochrome P-450, lysozyme and p53 protein human mRNAs. The same homology was estimated for this Alu in reversed orientation and Alus from the 3'UTRs of some other human mRNAs. In contrast, the homology between this 3' end tPA gene flanking Alu-repeat and other Alus dispersed throughout the gene introns either direct or reversed, was less than 70%. The polyadenylation signal AATAAA downstream the Alu and two nearby signals CACAG and GTGTT resembling consensus sequences CACAG and YGTGTTYY, respectively, were also detected. The two latter motifs located close to the 3' ends in most mammalian genes are likely to regulate mature mRNA formation. The comparison of the sequenced spaser flank adjacent to the tPA gene with short homologous sequence from the same genomic region primary structure reported previously has revealed discrepancies (substitutions, deletions or insertions) in 21 nucleotide positions. The nucleotide sequence of E. coli uvrB gene fragment (980 b.p.) is also reported. This E. coli gene fragment was cloned accidentally within the f1/BglII-fragment being an artifact of the host-vector system used.

Base Sequence↗