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T I Vavilova

Publications and source records attributed to T I Vavilova.

At least 19 recordsLinked to original sources
PubMed1994

[Hirschsprung's disease in newborns].

The authors examined and treated 52 newborn babies and infants with Hirschsprung's disease. The total form was encountered in 25%, the subtotal in 23.1%, the rectosigmoid in 36.5%, the rectal in 9.6%, and the supraanal in 5.8% of cases. The clinical picture was characterized by retention of meconium (94.2%), regurgitation or vomiting (75%), abdominal distention (100%). Irrigography with calculation of the rectosigmoid ratio was conducted in 35 children, histochemical examination in 46, and histological examination in 38 children. Twenty-four (68.5%) children had the third phase of disturbed proportion of the intestinal bacteria with clinical manifestations of enterocolitis. Emergency decompression of the intestine for low acute intestinal obstruction was carried out in 27 newborn babies. Twenty children were subjected to radical surgery in the first 2-4 months of life. The choice of the operative method was guided by the form of the disease and the length of the aganglionic zone.

Biopsy↗
PubMed1994

[The differential diagnosis of focal formations in the liver by using ultrasonography].

The results of hepatic ultrasonography were analyzed for 460 patients who had been treated surgically for cancer of the rectum. These were compared to histological evidence on the removed macropreparation and on intraoperative revision of the liver. Six types of the metastases were recognized to facilitate differential diagnosis of cancer with benign hepatic tumors, abscesses and focal fat dystrophy. Ultrasound semiotics of hemangioma, abscess, hepatic cyst is presented. Ultrasound accuracy in diagnosis of hepatic metastases reached 95%. It is shown that metastases of the same tumor type have different structure which may be related to the tumor histology and duration of the disease.

Adult↗
PubMed1991

[Characteristics of histochemical diagnosis of Hirschsprung disease in newborn infants].

The authors had 52 newborns and infants with Hirschsprung's disease under observation. The activity of tissue acetylcholinesterase (ASE) was tested by the Karnovsky-Ruts method in 35 cases. ACE activity was evaluated according to 5 types and a specific "newborn" type was set apart. A positive (42.9%) and weakly positive (28.6%) types of ACE activity prevailed in the neonatal period. Test for ACE activity performed in dynamics in 15 newborns showed gradual accumulation of ACE in the mucosa of the large intestine. In 6 (17.1%) babies a false-negative ACE activity was found, which was encountered in hypogangliosis and long-segmental forms. False-positive reactions were not encountered. Histochemical diagnosis made it possible to recognise Hirschprung's disease of the newborn in 82.9% of cases.

Acetylcholinesterase↗
PubMed1990

[Clinico-morphologic parallels in acute forms of Hirschsprung disease in newborns and infants].

39 newborns with an acute form of Hirschsprung's disease were under observation: rectal form 18%, recto-sigmoid 28.2%, subtotal 25.6%, total 28.2%. Clinical manifestations appeared soon after the birth and were characterized by the impediment of the meconium discharge, vomiting or eructations, abdominal swelling. The evaluation of the validity of histochemical and histological diagnostic methods in infants and morphologic description of the tissue acetylcholinesterase activity are presented. Hypoganglionic form of the disease was found in 4 cases. Clinical and morphologic picture of the hypogangliosis in newborns is described.

Acetylcholinesterase↗
PubMed1990

[Characteristics of clinical manifestations and diagnosis in Hirschsprung disease in newborn infants and young children].

Twenty two newborns and 10 young children with acute form of the Hirschsprung's disease were observed. In 1/3 of the patients, the Hirschsprung's disease was associated with congenital anomalies. The patients were treated by means of the performance of histochemical (15 cases), histologic (23) investigations and irrigography (19). A complex of the diagnostic measures used permitted to establish a reliable diagnosis.

Acetylcholinesterase↗
PubMed1989

[Clinico-morphologic data in decompensated colonic stasis].

The authors studied the results of surgical treatment of 97 patients with complicated form of the decompensated stage of chronic colonic stasis. The choice of the method and volume of the operation is determined by the location and spread of the stasis in the colon. Histological examination of material removed during the operation revealed predominantly dystrophic changes of the ganglionic cells of the musculo-intestinal plexus and hypertrophy and sclerosis of the muscular coat of the colon. The operation produced a good and satisfactory effect in 83.4% of patients.

Adult↗
PubMed1989

[Clinical aspects, diagnosis and treatment of hypoganglionosis of the colon in adults].

Surgical treatment of chronic colonic stasis is still a complicated and difficult for solution problem. The undertaken study characterizes one of the causes of chronic constipation in adults--the hypoganglionic variant of Hirschsprung's disease whose clinical course is marked by a prolonged period of compensation while the complex diagnosis is extremely difficult. The severe disorders of the motor-evacuation function of the large intestine make surgery necessary; operation leads to recovery of 96% of patients.

Adolescent↗
PubMed1985

[Preoperative diagnosis of Hirschsprung disease in children].

Twenty children of different age suspected of Hirschsprung's disease were examined. The complex examination included contrast irrigography, electromyography and determination of tissue acetylcholinesterase. The reliable diagnosis was established in 10 children. The distal border of agangliosis was found and thus the methods of treatment could be chosen.

Acetylcholinesterase↗