Biomedical subjects
T Ia Pshenichnikova
Publications and source records attributed to T Ia Pshenichnikova.
[The effect of a decrease in body weight in patients with the polycystic ovary syndrome].
Eighty patients with the polycystic ovaries syndrome and excessive body mass were examined. In 60 patients body mass reduction resulted from diets and in 20 it occurred over the course of acupuncture. Such treatment resulted in pregnancy in 27 (33.7%) patients. Therefore, diets or acupuncture for body mass reduction are recommended for patients with polycystic ovaries and obesity as the first stage of treatment.
[Immunologic aspects of external genital endometriosis].
Explore the source record for details and available documents.
[Danazol action on 5'-nucleotidase activity in mouse peritoneal macrophages].
The paper reports the results of danazol action in vivo and in vitro on 5'-nucleotidase activity of mouse peritoneal macrophages. The results showed, that danazol at a concentration of 10 M (the pharmacologic level in women taking 600 mg/day) significantly stimulated the enzyme activity.
[Diagnostic and surgical laparoscopy in polycystic ovary syndrome].
A total of 202 patients with polycystic ovaries were involved in examination. The study has distinguished the laparoscopic signs of polycystic ovaries: smooth glossy tightly stretched surface of the ovaries with a characteristic vascular pattern or loops; the presence of subcapsular cysts. Ovarian section shows small cysts with transparent or yellowish contents. The histologic signs are thickening of the protein coating, increased count of primary, secondary and cystic atretic follicles (by 2-5 times) and a lowered level of tertiary follicles. Clinical and hormonal signs include disordered rhythm of the menstrual cycle, stable anovulation, a high (over 2) LH/FSH index, an elevated T level. Laparoscopic resection of the ovaries to make their size normal is a method of choice among this technique, standard or wide ovarian biopsy.
[The place of laparoscopy in the diagnosis and treatment of ovarian cysts].
Laparoscopy as a diagnostic and therapeutic tool was tried in 56 patients. Laparoscopy was indicated in ovarian cysts detected by ultrasound, sterility, suspected external endometriosis. The diagnosis at laparoscopy coincided with histological pattern of the removed neoplasms in 100% in relation to malignancy. Endoscopic interventions had complications in 1.8% of cases. Recurrences were not recorded 18 months.
[Disorders of the hypothalamo-hypophyseal system as a cause of infertility in hyperprolactinemia].
The purpose of the study was to describe hypothalamopituitary functional status of females with infertility in combination with hyperprolactinemia. To this end, changes in prolactin, LH, FSH and TSH in response to the administration of releasing hormones (Gn--RH and TRH) and the dopamine antagonist metoclopramide were assessed in 28 patients with hyperprolactinemic amenorrhea and 5 normal cycling women. Lactotrophs were found to be resistant to functional tests, the resistance increasing as the prolactin level went up. Gonadotrophic and thyrotrophic response to functional tests, on the contrary, increased with the progress of hyperprolactinemia. A conclusion is drawn that stable hyperprolactinemia is a result of disturbance in lactotrophic receptor apparatus, for which reason lactotrophs are no longer sensitive to dophamine inhibiting effect on prolactin secretion.
[Diagnostic possibilities of laparoscopy in ovarian cysts].
Laparoscopy was used for the diagnosis of ovarian cysts in 90 patients. Ovarian cysts detected by ultrasonic examination, sterility, suspected external genital endometriosis were the indications for laparoscopy. In 32 cases the cysts were found in laparoscopy. In 23 patients a diagnostic puncture of the cyst and a subsequent cytologic examination were carried out. All the patients in whom ovarian cysts were diagnosed were operated on (endoscopically or via laparoscopy). Laparoscopic diagnoses coincided with the histologic findings in examinations of the removed formations in 100% of cases.
[Infertility caused by the polycystic ovary syndrome].
Explore the source record for details and available documents.
[Endocrine infertility in hyperprolactinemia].
Explore the source record for details and available documents.
[The role of repeated laparoscopy in the diagnosis of external genital endometriosis in infertile women].
Explore the source record for details and available documents.
[The role of place of endoscopic surgery in current gynecological research and clinical practice].
Explore the source record for details and available documents.
[Results of laparoscopy in patients with polycystic ovary syndrome after surgical treatment].
Laparoscopic studies have been done in 42 patients after laparotomic ovarian wedge resection (group 1), 12 women after laparoscopic ovarian thermocauterization (group 2) and 24 patients after laparoscopic ovarian wedge resection (group 3). Prominent adhesions were found out in the pelvis in group 1 women and milder ones in group 2 patients. The incidence of adhesions was significantly lower in group 3. It suggests that wedge resection using laparoscopy represents a method of choice for surgical ovarian correction.
[Various indicators of the androgenic status of healthy fertile women of Russian nationality].
Explore the source record for details and available documents.
[Effectiveness of infertility therapy in patients with hyperandrogenism].
170 patients of reproductive age with hyperandrogenemia and infertility were examined. 101 (59.4%) patients became pregnant after the complete therapy of infertility. The examination of patients after non-effective therapy stated that they had had more height stage of androgenemia and remarkable deviation in results of genetic observation in comparison with the same indications of the pregnant women.
[Comparative study of the diagnostic value of hysterosalpingography and laparoscopy].
A total of 100 women had either hysterosalpingography with watersoluble Verografin or lipidsoluble Jodlipol for the assessment of tubal patency. Of these, all had laparoscopy. Laparoscopy have been shown to be the best test of tubal abnormalities. Hysterosalpingraphy with lipidsoluble contrast medium is poorly informative while the method of investigating the tubal pathology and cannot be used in clinical practice.
[The polycystic ovary syndrome and increased body mass].
Eighty patients with the polycystic ovarys syndrome (PCOS) and excessive body weight were investigated. Weight loss was achieved by means of a diet in 60 patients, and acupuncture in 20 patients. This kind of treatment resulted in pregnancy in 27 (33.7%) patients. Therefore therapeutic diet or acupuncture may be recommended as the first stage of treatment for weight reduction in PCOS patients.
[Androgenization in patients with polycystic ovary syndrome].
150 infertile patients with the polycystic ovary syndrome (PCOS), aged 19 to 36 years, have been investigated. PCOS was diagnosed on the basis of clinical symptoms, and the diagnosis was verified by laparoscopy, followed by histologic investigation of ovarian biopsy specimens. Hirsutism was found in 43% of the patients, while hair growth was marginal in 30% and normal in 27%. Testosterone (T) levels were increased significantly (p less than 0.05) in the PCOS patients with hirsutism or marginal hair growth, as compared to reference values.