Biomedical subjects

T Igari

Publications and source records attributed to T Igari.

112 records · Page 7Linked to original sources

PubMedDate not supplied

Extracorporeal circulation with perfluorochemicals (Fluosol-DA).

Experimental studies on extracorporeal circulation (ECC) with perfluorochemicals (Fluosol-DA) as a perfusate was performed to examine oxygen carrying capacity and its organ distribution using eight calves. Approximately 80% of the circulating blood volume was withdrawn before ECC and reinfused after completion of ECC. ECC time was 60 minutes in five of the calves and 120 minutes in three of the calves. Hct and Hb decreased to 4-12% and 1.7-6.6 g/dl during ECC. Fct (Fluorocrit: volume percentage of Fluosol-DA) ranged between 5 and 10%. PaO2 and PvO2 were 432-543 mmHg and 93-164 mmHg. Sixty-seven to 86% of the oxygen consumed by the tissues was delivered by Fluosol-DA. One of the complications of ECC with Fluosol-DA, hemolysis was observed in four of the calves which had a relatively high level of Fluosol-DA retention (13.9 g/kg) in the body after ECC. The retention volume of the other four calves which did not show hemolysis was 10.0 g/kg. Retention of Fluosol-DA after ECC was found to be greater in the reticuloendothelial system of the calves sacrificed earlier and became trace or minimal after 10 months.

Alanine Transaminase↗

PubMedDate not supplied

[External valvuloplasty under preoperative angioscopic control].

Intraoperative angioscopy was applied to evaluate the venous valvular incompetence and perform external valvuloplasty in case of venous reflux. Sixty-seven limbs, 43 cases of primary varicose veins were examined using intraoperative angioscopy and the angioscopic findings of the incompetent venous valves were classified into three types as follows: valves with elongated and atrophic cusps 43 (50%)--type I, values with expanded and depressed commissures 36 (42%)--type II, and valves with perforated cusps or other changes 7 (8%)--type III, according to the angioscopie findings, external valvuloplasty was done in 31 subterminal valves of the long saphenous veins and 7 highest valves of the superficial femoral vein. Our external valvuloplasty consisted of two techniques. The first was the total plication technique for valvular annulus by a running suture of prolene and the second was by the venocuff sleeve of the autogenetic femorofascial band. The degree of plication was decided by angioscopic observation. Postoperative observation periods were from 2 to 28 months. There was no recurrence of varicose veins or prominent venous reflux. The application of intraoperative angioscopy is therefore useful for the choosing appropriate surgical procedures and for the evaluation of venous valvuloplasty.

Adult↗

PubMedDate not supplied

Hassab operation with intraoperative endoscopic injection sclerotherapy ("Hassab-EIS") for esophagogastric varices: with an autopsied case after excessive gastric vascular damage.

BACKGROUND/AIMS: Endoscopic injection sclerotherapy (EIS) does not always treat advanced esophagogastric varices completely. Moreover, it may cause deterioration of gastric varices and may result in gastric hemorrhages. We would like to emphasize a combination treatment of the obliteration therapy of intramural varices by EIS and the transabdominal devascularization with splenectomy by Hassab's operation for such advanced esophagogastric varices. The purpose of this study is to develop an effective, less-painful procedure, having the fewest operational risks and a minimum number of treatment days. MATERIALS AND METHODS: We tried both therapies simultaneously (Hassab+EIS) on four patients with esophagogastric varices. RESULTS: Excessive vessel damage occurred in one patient which resulted in postoperative bleeding. He subsequently fell into sepsis/DIC and eventually died on the 9th POD. The three other patients are doing well and required less hospitalization time and a fewer number of additional EIS treatments than the esophageal transection group or the Hassab's operation group. CONCLUSION: From the reconsideration of the autopsied case, it is important to limit the distribution of the sclerosant only in the varicose veins of the lower esophagus and the upper stomach.

Adult↗

PubMedDate not supplied

Minute mixed hepatoma with two components: hepatocellular and cholangiocarcinoma, which developed on liver cirrhosis with HCV.

Mixed type hepatoma with two components, hepatocellular and cholangiocellular carcinoma, is very rare. We encountered a case of a single and minute mixed type hepatoma developing on liver cirrhosis in a patient with persistent hepatitis C viral infection. Histologically, the two-type cancer tissue existed in a nodule with a maximal diameter of approximately 20 mm, and the cholangiocellular carcinoma occupied about 70% of the tumor. The original cell of the mixed type hepatoma is unknown, but this case suggests that a bipotential cell developing into hepatocellular and cholangiocellular carcinoma may be the origin.

Carcinoma, Hepatocellular↗