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T Ino

Publications and source records attributed to T Ino.

At least 163 records · Page 9Linked to original sources
PubMed1993

[Preoperative evaluation of a distal aortic arch aneurysm by spiral CT with three-dimensional reconstruction].

Sixty-seven-year-old male with a distal aortic arch aneurysm was evaluated by spiral CT with three-dimensional reconstruction. Spiral CT allows rapid data acquisition through an entire anatomic region during a single breath hold. The helically acquired data undergo interpolation. Transverse images are reconstructed with slice intervals 1-4 mm apart. Three-dimensional images were generated by these data with the transverse images. The entire anatomical correlation with the aneurysm and the aortic arch branches was clearly recognized by these three-dimensional images. Preoperative evaluation of the distal aortic arch aneurysm by spiral CT with three-dimensional reconstruction was useful for the surgical treatment.

Aged↗
PubMed1993

[Surgical treatment of adult secundum ASD with severe pulmonary hypertension--two case reports].

Indication and treatment of adult secundum ASD with severe PH was discussed in two surgical cases. Case 1: 32-year-old woman with dyspnea on exercise. After 100% O2 inhalation, PA systolic pressure changed from 103 to 104 mmHg, left to right shunt ratio changed from 18.2% to 52.2%, Qp/Qs changed from 1.07 to 2.08, Rp/Rs changed from 0.58 to 0.28, PVR changed from 1606 to 805 dyne.sec.cm-5 respectively. Because the reversibility of pulmonary obstructive disease was recognized, ASD closure was performed. Her activity became well, and PVR was decreased to 758 after the operation. Case 2: 63-year-old man with dyspnea on exercise. After 100% O2 inhalation, PA systolic pressure changed from 102 to 95 mmHg, Left to right shunt ratio changed 31.9 to 51.0%, Qp/Qs changed from 1.30 to 2.0, Rp/Rs changed from 0.65 to 0.39, PVR changed from 1257 to 806 dyne.sec.cm-5. After the operation, he got well, and PA systolic pressure was decreased to 85 mmHg, PVR was 620. 100% O2 inhalation test was valuable to evaluate the reversibility of pulmonary obstructive state and to decide the surgical indication.

Adult↗
PubMed1993

[Selective cerebral perfusion with cold blood for the surgical treatment of aortic arch aneurysm].

To determine whether the selective cerebral perfusion with cold blood is useful for repair of aortic arch aneurysm, 7 consecutive patients with aneurysms were examined (October, 1991-July, 1992). Four of 7 patients (57%) required emergency surgery due to the aortic rupture. Surgical repair was performed under the moderate core hypothermia (20-25 degrees C) to avoid prolonged cardio-pulmonary bypass (CPB), and the selective cerebral perfusion with oxygenated cold blood (16 degrees C, 350-450 ml/min) was employed for cerebral protection. The selective cerebral perfusion system was easily added to the ordinary CPB system with low priming volume (150 ml). The mean cerebral perfusion time, the mean cardiac arrest time, and the mean CPB time in this series were 93 min, 93 min, and 201 min, respectively. One of 7 surgical cases (14%) died due to the postoperative complication (multiple organ failure). Other 6 patients recovered and discharged. Successful cerebral protection and avoidance of prolonged CPB may be achieved by this unique method. The selective cerebral perfusion with cold blood may be one of the useful and reliable methods for repair of aortic arch aneurysm.

Adult↗
PubMed1993

[Replacement of ascending and transverse aorta using zero-porocity gelatin impregnated graft].

Gelatin impregnated Dacron graft was used without preclotting for the replacement of ascending and transverse aorta in 11 cases. The replacement of transverse aorta was performed in six patients with atherosclerotic aortic arch aneurysms and two patients with aortic dissections. The replacement of ascending aorta was performed in two patients with annlo-aortic ectasia and one patient with aortic dissection. Five of 11 patients (45%) needed emergency surgery due to the aortic rupture. Bleeding from the graft was not recognized clinically in all cases during the full heparinized cardiopulmonary bypass ranged from 153 min to 260 min. One patient (9%) with the rupture of transverse aorta died at the 7 th post operative day due to the multiple organ failure. No complication related to the graft was observed in all cases. Zero-porocity gelatin impregnated graft was useful for the replacement of aorta, especially for the replacement of ruptured ascending and transverse aorta in emergency situation.

Adult↗
PubMed1993

[A case report of the preoperative diagnosis of thoracoabdominal aortic aneurysm by three-dimensional CT angiography].

A sixty-year-old woman with the thoracoabdominal aortic aneurysm (7 cm in the diameter) was evaluated by the newly developed three-dimensional CT angiography. The thoracoabdominal aortic aneurysm was scanned by spiral CT and three-dimensional images were generated preoperatively. The three-dimensional structures of the thoracoabdominal aorta with the aneurysm, the celiac trunk and the superior mesenteric artery were clearly visualized by this method. The thoracoabdominal aorta was replaced by the graft with the reconstruction of celiac trunk. The post-operative course was uneventful. The preoperative diagnosis of thoracoabdominal aortic aneurysm by this method was very useful in the determination of operative procedure in this case. Three-dimensional CT angiography may be the useful method in the preoperative diagnosis of the aortic surgery.

Aorta, Abdominal↗
PubMed1993

[Selective cerebral perfusion with cold blood for the aortic arch surgery].

In seventeen patients with aortic arch aneurysms including seven emergency cases, the selective cerebral perfusion with cold blood (16 degrees C) was applied for the cerebral protection during the surgical procedure. Fifteen of them (88%) including the patient with the long cerebral perfusion (236 min) recovered perfectly and discharged. The selective cerebral perfusion with cold blood may be one of the safe and reliable methods for the repair of aortic arch aneurysm.

Adult↗
PubMed1993

[Preoperative diagnosis of the thoracic aortic aneurysm by three-dimensional CT angiography].

Serial eight patients with thoracic aortic aneurysms were evaluated by a newly developed three-dimensional CT angiography (3D-CT) from December 1992 to January 1993. The patients include 3 aortic dissections, 3 aortic arch aneurysms, one descending aortic aneurysm and one thoracoabdominal aortic aneurysm. The surgical treatment was performed after the evaluation of 3D-CT, and the operative findings were compared to the three-dimensional images reconstructed by 3D-CT in all patients. Three-dimensional displays were achieved using the unique method of data collection of the helical (spiral) scanner with continuous tube rotation and continuous table feed. A intravenous contrast material was used to image the thoracic aorta and major aortic branches with the single-breath-hold technique. Two and three-dimensional images reconstructed by 3D-CT were displayed within 10-20 minutes after the scanning. These three-dimensional images of the aortic lesions could be displayed in any angle we chose. Three-dimensional structures of the thoracic aorta and major aortic branches were clearly visualized and easily recognized by 3D-CT. These images were similar to the intraoperative findings and were quite useful to determine the operative procedure. The successful repair of thoracic aortic aneurysm was achieved in all cases. 3D-CT is a new and attractive modality to assess the vascular system. Although our experience is limited, 3D-CT may be a useful and powerful diagnostic method for the surgical treatment of thoracic aortic aneurysm.

Adult↗
PubMed1993

[Rearrangements of immunoglobulin light chain and heavy chain constant region genes in B-cell malignancies].

We analyzed immunoglobulin (Ig) gene rearrangements in 69 patients with B-cell malignancies by Southern hybridization. We used 5 probes which covered JH 5'S mu and S gamma 3 loci of the Ig heavy (IgH) chain gene, and C kappa and kappa de loci of the Ig light (IgL) chain kappa gene, respectively. DNA rearrangements were observed in 68 out of the 69 patients using the JH probe. In 97% (33/34) of patients with non-Hodgkin's lymphoma (NHL), 100% (5/5) of chronic lymphocytic leukemia (CLL), 42% (10/24) of non-T cell acute lymphoblastic leukemia (non-T ALL), and in 0% (0/4) of chronic myelogenous leukemia lymphoid crisis (CML-LBC), the rearrangements were detected by C kappa and/or kappa de probes. Furthermore, the genotype of the light chain was defined by rearrangement patterns of these 2 probes. The by using the 5'S mu-probe, class switch recombinations were detected in 76% (25/33) of NHL, 20% (1/5) of CLL, 17% (4/24) of non-T ALL, and in 0% (0/4) of CML-LBC. Among them, 1 case of IgM NHL and 3 cases of double bearer NHL had rearranged on both IgH alleles by the constant region. The results of this study indicate that genotypes correspond well to phenotypes of B-cell malignancies and that the determination of genotype will be useful for making an exact diagnosis of B-cell malignancies.

DNA, Neoplasm↗
PubMed1993

[Surgical treatment of aberrant right subclavian artery aneurysm].

A 77-year-old female was admitted with dysphagia and back pain. Angiography revealed an aberrant origin of the right subclavian artery from the posterior aspect of the proximal descending thoracic aorta just distal to the origin of the left subclavian artery. The origin of the right subclavian artery was aneurysmal (maximum transverse diameter was 8 cm), and this aneurysm was causing compression of the esophagus. The patient was treated by Teflon patch graft aortoplasty and right subclavian artery reconstruction with the aid of cardiopulmonary bypass and hypothermic selective cerebral perfusion. Postoperative course was uneventful and there were no major complications.

Aged↗
PubMed1993

[Primary chondrosarcoma of the pulmonary artery].

A 69-year-old woman who had progressive dyspnea, edema and oliguria was diagnosed as primary sarcoma arising in the pulmonary trunk by preoperative examination. She received thoracotomy and total resection of the tumor in the pulmonary trunk utilizing cardiopulmonary bypass. A microscopical examination revealed that the tumor had the features of the chondrosarcoma originating in the pulmonary artery. There have been very few reports on chondrosarcoma in the pulmonary artery. It is reported that the prognosis of the sarcoma in the pulmonary artery is less favorable, however, this case had uneventfully postoperative course and no signs of recurrence one year after operation.

Aged↗
PubMed1992

Topographic projections from the subiculum to the limbic regions of the medial frontal cortex in the cat.

When WGA-HRP was injected into the subicular cortex of the ventral hippocampal formation (Hv) in the cat, terminal labeling was seen ipsilaterally in the caudoventral parts of the medial frontal cortex: in the infralimbic cortex (area 25), ventral part of the prelimbic cortex (area 32), and caudoventral part of the orbitofrontal cortex (area 12). The terminal labeling was observed in all cortical layers except layer 1. The cells of origin of these projections were then confirmed to be pyramidal neurons in the subiculum of the Hv. The projections were topographically organized: the temporal-septal shift along the long axis of the subiculum of the Hv corresponded to a rostroventral-caudodorsal shift in the anterogradely labeled limbic regions of the medial frontal cortex.

Animals↗
PubMed1992

Alternating non-cross-resistant chemotherapy for non-Hodgkin's lymphoma of intermediate-grade and high-grade malignancy. A pilot study.

Thirty-two patients with advanced non-Hodgkin's lymphoma (NHL) with aggressive histologic findings were treated with cyclophosphamide, doxorubicin, methotrexate with leucovorin rescue, bleomycin, vincristine, etoposide, ifosfamide, and prednisolone (CAMBO-VIP), in which presumably non-cross-resistant myelosuppressive and nonmyelosuppressive agents were administered during alternate weeks for 12 weeks. To ensure the high-dose intensity of the protocol, dose reduction and delay in treatment were minimized. Three patients were treated inadequately. Twenty-six (89.7%) of 29 evaluable patients had a complete response, and three had a good partial response. Relapse occurred in four patients, with a median follow-up of 29 months. The actuarial overall survival and disease-free survival were estimated to be 87.6% and 75.9%, respectively. The CAMBO-VIP treatment was well tolerated; myelosuppression was severe but transient and caused no serious infections. Side effects that affected dose intensity were oral ulceration, occurring in 28 patients, and blister formation under the thickened skin of palms and/or soles, followed by desquamation (5 patients). Hepatic toxicity was generally mild to moderate; it was severe in one patient. A 12-week regimen of CAMBO-VIP was effective for advanced NHL with aggressive histologic findings.

Adolescent↗
PubMed1992

Plasma endothelin concentration: relation with vascular resistance and comparison before and after balloon dilatation procedures.

Endothelin (ET) is a potent vasoconstrictor peptide with an as yet uncertain physiological role in cardiovascular disease. We measured blood plasma ET concentrations using a recently developed radioimmunoassay and analysed the relations between ET concentration, systemic arterial pressure and systemic vascular resistance. In addition, ET levels before and after percutaneous balloon valvuloplasty and angioplasty were measured. Fifty-one patients were studied: (1) 13 patients with small left-to-right shunting or Kawasaki heart disease (age ranged from 4 to 144 months); (2) 10 patients who had undergone balloon valvuloplasty or angioplasty (age ranged from 1 to 233 months) and (3) 28 healthy infants and children (age ranged from 3 to 152 months). Systemic vascular resistance was calculated by the formula (mean aortic pressure--mean right atrial pressure) X 80/cardiac output (dyne.sec.cm-5). Plasma ET concentrations in healthy children less than 2 years were significantly higher than those over 2 years (2.48 +/- 0.62 vs 1.31 +/- 0.53 pg/ml). In eight patients in groups 1 and 2, plasma ET concentration in the pulmonary artery (2.00 +/- 0.43 pg/ml) was significantly lower than that in the femoral vein (2.39 +/- 0.69 pg/ml) and aorta (2.23 +/- 0.59 pg/ml), suggesting ET secretion derived from endothelial cells in peripheral pulmonary vessels. There was a significant positive correlation between ET concentrations in the femoral vein and systemic vascular resistance (r = 0.55, p less than 0.05). After balloon dilatation ET concentration rose from 2.15 +/- 0.82 pg/ml to 2.61 +/- 1.38 pg/ml.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1992

Hemodynamic evaluation of a new left ventricular assist device: an integrated cardioassist catheter as a pulsatile left ventricle-femoral artery bypass.

We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether this pulsatile LV-aorta bypass is superior to the IABP from a hemodynamic viewpoint. Ten dogs with profound heart failure were placed on this device, and hemodynamic measurements were performed under on-off study of this system. The results revealed a significant increase of mean aortic pressure, total cardiac output, and myocardial blood flow, and a significant reduction of left atrial (LA) pressure and LV afterload estimated by diastolic pressure-time index/tension-time index (DPTI/TTI) measurement compared with baseline values and also with IABP exertion alone. These findings suggest that this system is of clinical value for supporting an impaired LV that is intractable under IABP counterpulsation.

Animals↗
PubMed1992

A case of cardiac foreign bodies associated with four types of tachycardias.

A case of cardiac foreign bodies leading to development of four varieties of automatic tachycardia is reported. A 51-year-old male with aortic regurgitation was admitted to our hospital because of palpitations. An electrocardiogram revealed junctional tachycardia with or without left bundle branch block, and two types of fascicular tachycardias. Computed tomography showed metallic foreign bodies from a fractured guidewire in the membranous portion of the interventricular septum, which was inadvertently retained when he underwent diagnostic cardiac catheterization at the age of 27.

Bundle-Branch Block↗
PubMed1992

[A case of Candida albicans endocarditis with impaired lung function].

A 53-year-old male was admitted to the hospital because of Candida albicans endocarditis. He had had a thoracoplasty due to pulmonary tuberculosis and showed severe restructive lung function. In 1987 and '89, trachiostomy was made because of respiratory failure. The patient was well until nine months earlier, when he consulted a physician because of fever. The investigations failed in finding the cause of the fever. He was administered antituberculosis agents and antiinflammatory drugs but had a fever every day. Two months before admission, a cardiac ultrasonographic study showed evident vegetations with mitral regurgitation. From the above course and examinations, a diagnosis of Candida albicans endocarditis was made. Infusions of CEZ, TOB, PIPC and miconazole for more than one month was ineffective. In November, 1990, he was referred to our medical center for the purpose of operation. A blood culture proved Candida albicans infection. An intravenous administration of fluconazole 400 mg/day was begun. However, there was pulmonary bleeding probably due to heparin used for prevention of atrial thrombosis and he developed fever, hypoexemia, ventricular tachycardia, and hyponatremia. He underwent mitral-valve replacement with a SJM valve. Culture of the vegetated mitral valve again proved Candida albicans. After operation, hypoexemia, ventricular tachycardia, hyponatremia were improved gradually. However he had an eosinophilia, eruption, and dyspnea. We suspected a drug eruption of fluconazole. Lymphocyte stimulating test of fluconazole proved positive. After the episode, he had no symptoms and was discharged.

Candidiasis↗
PubMed1992

Intermediate-term results of balloon valvuloplasty for isolated and complicated pulmonary valve stenosis.

UNLABELLED: The purpose of this study is to report our experience regarding the acute and intermediate-term results of balloon pulmonary valvuloplasty (BPV) in various types of congenital pulmonary valve stenosis. METHODS AND RESULTS: Twenty-four consecutive patients with a median age of 6.6 years (ranging from 1 month to 24 years old) underwent BPV between January 1988 and September 1991. These patients were divided into 2 groups; Group 1 consisting of 13 patients with isolated pulmonary valve stenosis, and Group 2 consisting of 11 patients with complicated pulmonary valve stenosis (supravalvular, subvalvular, valved conduit and post-right ventricular outflow reconstruction). Mean peak systolic pressure gradients from the right ventricle to the pulmonary artery were as follows: In group 1, 48 +/- 21 (mean +/- SD) mmHg before BPV, 18 +/- 8 mmHg immediately after BPV and 13 +/- 5 mmHg at the longest follow-up based on catheterization or Doppler echocardiographic studies. The gradients in group 2 were 65 +/- 28 mmHg before BPV, 46 +/- 25 mmHg immediately after BPV and 47 +/- 21 mmHg at the longest follow-up. CONCLUSIONS: BPV provides both acute and intermediate-term gradient relief in patients with isolated pulmonary valve stenosis. In complicated pulmonary valve stenosis, on the other hand, the effect of BPV was unsatisfactory and appears to depend on the mechanism of associated obstruction. Therefore accurate evaluation of the anatomy of associated obstruction in the pulmonary valve region is needed to determine that BPV is indicated.

Adolescent↗