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Biomedical subjects

T Ionescu

Publications and source records attributed to T Ionescu.

At least 19 recordsLinked to original sources

[The surgical treatment of haemophilic arthropathy (author's transl)].

The authors have operated on 13 haemophilic joints. The operation included 5 knee synovectomies of the knee, 2 corrective osteotomies, 4 soft tissue procedures on the knee or foot (tendon lengthening, capsulotomy), 1 arthrodesis of knee and 1 excision of heterotopic ossification. The type of operation needed varied with the degree of involvement. Indications for associated haematological treatment are given. The indications were both preventive and curative. The results were gratifying, although two cases of post-operative infection were seen.

Adolescent↗

The presence of complement fixing antibodies to Rous sarcoma virus (Schmidt-Ruppin strain) in patients with various forms of neoplasia.

The presence in men of antibodies to Rous sarcoma virus, an oncogenic virus of avian origin, was demonstrated. The highest antibody incidence was found in patients with various forms of cancer (34.4%, as against the value of 12% recorded in blood donors); these patients also showed an increased antibody level - 1/64 titers were detected in 43 out of 7 patients. The possibility of a human infection with animal oncogenic viruses is discussed, without excluding the hypothesis of a paraimmune reaction.

Antibodies, Viral↗

Studies on the presence of viral antibodies in patients with various forms of malignant neoplasia.

The study of viral antibodies in 6714 sera demonstrated that the level of antibodies to infectious viruses was the same in cancer patients as in controls. However, the patients with various forms of neoplasia showed a considerable percentage and high antibody levels to viruses with oncogenic potential for animals (adenovirus, SV40, Rous virus) or involved in human carcinogenesis (herpes virus).

Adenoviridae↗