Priapism in sickle cell disease: possible contributory effect of cocaine use.
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Biomedical subjects
Publications and source records attributed to T Ivey.
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In 94 patients, 137 permanent Silastic central venous catheters were inserted. Of these, 53 catheters were removed because of catheter related problems. The average duration of catheter use was 12 months. However, the catheter was only removed once every 31 patient months because of catheter dysfunction and once every 82 months because of catheter related sepsis. None of the patients died from catheter related septicemia. We believe this low complication rate of catheter related complications represents an acceptable risk for those patients who will benefit from home parenteral nutrition.
The administration of intrapleural bacillus Calmette-Guérin (BCG) alone and intrapleural BCG plus levamisole was compared to placebo in patients with resectable, non-small cell cancer of the lung. This report is based on an interim analysis of 100 eligible patients with a median followup of 245 days. No significant treatment effects are apparent at the present time, although current trends are consistent with an approximate 30% reduction in recurrence rate in patients receiving intrapleural BCG. There is little evidence to suggest that the addition of levamisole will contribute to this effect. A relationship between purified protein derivative conversion and tumor recurrence is apparent. Failure to manifest purified protein derivative conversion following administration of intrapleural BCG is associated with a significantly greater risk of tumor recurrence.
Gross and histologic studies of human and canine latissimus dorsi muscle were carried out to identify anatomic and histochemical properties that may be relevant to its use as a resource muscle, particularly for heart reconstruction. In both human and canine latissimus dorsi, three distinct muscle segments were observed, differing in direction of fibers, fiber characteristics, thickness, and blood supply. The entire canine latissimus dorsi could also be separated into superficial and deep layers, whereas only the anterolateral segment of human latissimus dorsi was separated further by the neurovascular bundle. Histochemical studies suggested significant differences between the ratios of fast to slow fibers in the superior and anterolateral segments of human muscle. Variation in size, weight, and shape within and between subjects demonstrates a need for careful evaluation of the potential resource muscle.