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Biomedical subjects

T Izukura

Publications and source records attributed to T Izukura.

11 recordsLinked to original sources
PubMed1993

Rationale of surgical management for recurrent hepatocellular carcinoma.

From 1979 to 1991, 100 patients with hepatocellular carcinoma (HCC) underwent a curative hepatic resection in our institution. Five patients died within 1 month, and four patients died after longer than 1 month hospitalization. The remaining 91 patients were closely followed. Intrahepatic recurrences became obvious in 36 (40%) of these 91 patients during the follow-up period. Second operation was carried out on 22 patients, and the re-extirpation of HCCs was performed on 16 patients. Pure ethanol injection into the tumor associated with implantation of the Infuse-A-Port (Infusaid Inc., Norwood, MA) for intra-arterial infusion of anti-cancer agents was performed on the remaining six patients. Of these 22 patients, 15 are still alive, eight being free of HCC and seven with the disease, for 13 to 92 months after the first operation. The cumulative survival rate of 22 patients with repeated operations was significantly better than that of 14 patients who were treated conservatively (p < 0.05). The adequate surgical management of recurrent HCC is considered as most important in achieving better prognosis of HCC.

Adult↗
PubMed1984

Abnormal persistence of the right vitelline vein.

The authors describe a case of intestinal obstruction due to a mesodiverticular band, in which both vitelline artery and vein remnants were affirmed to be present histologically. Reviewing case reports in literature, it was revealed that the vein found in the band was the right vitelline vein remnant and that this was an important fact which proved the hypothesis that the superior mesenteric vein derives from the right vitelline vein.

Arteries↗
PubMed1982

Successful Rastelli operation in infant with complete transposition of great arteries, levoposition of aorta, and subaortic ventricular septal defect.

A 10-month-old infant with complete transposition of the great arteries (TGA) [S,D,L] and large ventricular septal defect (VSD) without left ventricular outflow tract obstruction underwent successful Rastelli operation utilizing a 16 mm Hancock graft. The VSD was subaortic, and an internal conduit was placed easily. Postoperative hemodynamic conditions were satisfactory, and the patient was doing well eighteen months after operation. The feasibility of primary Rastelli operation for TGA and VSD in young infants is described.

Aorta↗
PubMed1978

[Chemotherapy of peritonitis with particular reference to concentrations of sulbenicillin in human ascites (author's transl)].

Twenty-seven patients with peritonitis to whom a drain was applied were given sulbenicillin (SBPC), a broad-spectrum antibiotic, which has so little hepatic and renal toxicity that massive doses may be feasible, and examination was made as to its therapeutic effects and concentrations of the antibiotic in the ascites. Daily dosage of SBPC was 10g in two divided doses in most cases given by the intravenous infusion. Medication was continued for 3 approximately 15 days. The highest daily dosage was 20g and the largest total dosage reached 190g, but there was no adverse reaction except for one case of a slight anemia. Peritonitis complicated appendicitis, adnexitis, duodenal ulcer perforation, intestinal obstruction or trauma as its primary disease. No difference in the therapeutic effect existed among the primary diseases. The response to SBPC treatment was excellent in 8 of the 27 patients and good in 17. Two patients failed to respond to the therapy. When SBPC was given just before operation, the SBPC concentration in ascites obtained at operation was 112 microgram/ml in 2 cases. The SBPC concentrations in ascites were examined following intravenous infusion of 5g over an hour, and a peak concentration of 94.7 microgram/ml was obtained at the completion of infusion (an hour after the start of infusion), which gradually decreased thereafter. In the ascites excreted from the drain after operation, a high concentration of 12.7 approximately 90.2 microgram/ml (mean: 51.7 +/- 7.7 microgram/ml) was obtained on the day after the operation day, but the concentration was lower thereafter. The SBPC concentrations in ascites were compared as regards the sites of drainage (Winslow's foramen, ileocecum and Douglas' fold), but no particular difference was observed. The SBPC concentrations in ascites after operation were in inverse proportion to the alleviation of peritonitis. They were higher when the inflammation was severer.

Adolescent↗