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T J Andary

Publications and source records attributed to T J Andary.

9 recordsLinked to original sources

A scanning electron microscopy study of the effect of proteinase inhibitors on mouse uterine morphology.

The luminal uterine surface of mice was examined by scanning electron microscopy after a 24 h treatment with basic pancreatic trypsin inhibitor (BPTI) or L-1-tosylamido-2-phenylethyl chloromethyl ketone (TPCK) administered as a single injection or from a slow release capsule on Day 2 p.c. in doses known to impair fertility. The effect of BPTI was slight, some swelling of cells and loss of microvilli. TPCK, on the other hand, caused disruption of the epithelium through swelling and sloughing of cells, sporadic loss of microvilli, and the presence of red blood cells.

Animals↗

Tryptic- and chymotryptic-like proteinases in early and late preimplantation mouse blastocysts.

Neutral tryptic- and chymotryptic-like enzyme activities have been identified in extracts of early and late mouse blastocyts. The enzyme activities are distinguishable my means of: (a) reactivity with specific naphthylamide derivatives; (b) reactivity with tosyl-L-lysine-chloromethyl ketone or L-tosylamido-2-phenylethyl-chloromethyl ketone, respectively; (c) electrophoretic mobilities; and (d) specific activity profiles of late vs. early blastocysts.

Animals↗