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Biomedical subjects

T J Baker

Publications and source records attributed to T J Baker.

10 recordsLinked to original sources

The relationship of the superficial and deep facial fascias: relevance to rhytidectomy and aging.

Controversy persists regarding the relationship of the superficial facial fascia (SMAS) to the mimetic muscles, deep facial fascia, and underlying facial nerve branches. Using fresh cadaver dissection, and supplemented by several hundred intraoperative dissections, we studied facial soft-tissue anatomy. The facial soft-tissue architecture can be described as being arranged in a series of concentric layers: skin, subcutaneous fat, superficial fascia, mimetic muscle, deep facial fascia (parotidomasseteric fascia), and the plane containing the facial nerve, parotid duct, and buccal fat pad. The anatomic relationships existing within the facial soft-tissue layers are (1) the superficial facial fascia invests the superficially situated mimetic muscles (platysma, orbicularis oculi, and zygomaticus major and minor); (2) the deep facial fascia represents a continuation of the deep cervical fascia cephalad into the face, the importance of which lies in the fact that the facial nerve branches within the cheek lie deep to this deep fascial layer; and (3) two types of relationships exist between the superficial and deep facial fascias: In some regions of the face, these fascial planes are separated by an areolar plane, and in other regions of the face, the superficial and deep fascia are intimately adherent to one another through a series of dense fibrous attachments. The layers of the facial soft tissue are supported in normal anatomic position by a series of retaining ligaments that run from deep, fixed facial structures to the overlying dermis. Two types of retaining ligaments are noted as defined by their origin, either from bone or from other fixed structures within the face.(ABSTRACT TRUNCATED AT 250 WORDS)

Aging

Production, characterisation and use of monoclonal antibodies to human interleukin-5 in an enzyme-linked immunosorbent assay.

Two mouse monoclonal antibodies (Mabs) against recombinant human interleukin-5(rhIL-5) have been produced, characterised and purified. Both are IgG1 antibodies and neutralised the activity of rhIL-5 in the B13 assay. Neither Mab cross-reacted with mouse IL-5. A two-site sandwich enzyme-linked immunosorbent assay (ELISA) was developed with different combinations of the mouse Mabs and also a rat anti-mouse IL-5 Mab, TRFK5, which also has activity against rhIL-5. The most sensitive assay, with a lower detection limit of 0.5 ng/ml IL-5, used TRFK5 as the capture antibody and the mouse anti-human IL-5 Mab as second antibody. The sensitivity of this assay was increased by an enhanced chemiluminescent reagent and resulted in a lower limit of detection around 40 pg/ml IL-5.

Animals

The anatomy and clinical applications of the buccal fat pad.

The buccal fat pad is an anatomically complex structure that has great importance in facial contour. In properly selected individuals, judicious harvesting of buccal fat can produce dramatic changes in facial appearance by reducing the fullness of the cheek and highlighting the malar eminences. Using fresh cadaver dissection, the anatomy of the buccal fat pad is delineated and its relationship to the masticatory space, facial nerve, and parotid duct is defined. An intraoral approach for buccal fat harvesting is described based on these anatomic findings. Clinical experience manipulating the buccal fat pad for aesthetic modification of facial contour is illustrated.

Adipose Tissue

Chemical peeling as a practical method for removing rhytides of the upper lip.

Chemical peeling is a safe, effective method for removing upper lip lines, or rhytides, over a long period of time. While the predictable, undesirable sequela of loss of pigmentation occurs in a significant number of patients, the effectiveness and safety of the procedure seem to outweigh this problem. Chemical peeling has become an accepted and effective tool for eliminating upper lip lines due to aging, and should be considered by physicians undertaking treatment of the wrinkled upper lip.

Chemexfoliation

Chemical peel.

Chemical face peeling as described in this article produces gross and microscopic changes in the skin which are permanent. The most important aspect in assuring the success of this procedure is the proper selection of patients. The primary use of this procedure is for the purpose of eliminating wrinkles, whether as the primary or ancillary procedure, such as regional peeling. Chemical peeling of the face is a valuable adjunct in the treatment of the aging face and can produce some rather dramatic results with the careful selection of patients and meticulous attention to detail in carrying out the peel, as well as the exact adherence to the post peel instructions by the patient.

Adolescent

Upper lid blepharoplasty.

We reviewed, retrospectively, our upper lid blepharoplasties to critically compare our own postoperative results after (1) conventional blepharoplasty, or (2) fixation of the levator aponeurosis to the lower margin of the orbicularis, or (3) fixation of the levator to the lower margins of the orbicularis and the skin. We found no demonstrable difference in our results with these 3 techniques. It is our opinion that the standard conventional blepharoplasty (including excision of a strip of orbicularis muscle) is preferable for use in most caucasian eyelids. The results are as good, it is simple, and it is less likely to cause problems.

Eyelids

Rhytidectomy: a statistical analysis.

A statistical analysis of 1,500 consecutive rhytidectomies is presented. In rhytidectomy, complications occur in a significant percentage of the operations. The plastic surgeon must be aware of the incidence and significance of these complications, and also he must know how to avoid or manage them.

Age Factors