PubMed Health⌕ Search

Biomedical subjects

T J Giuffrida

Publications and source records attributed to T J Giuffrida.

3 recordsLinked to original sources

Localized cutaneous metastases from an atypical fibroxanthoma.

BACKGROUND: Atypical fibroxanthoma is a rare cutaneous spindle cell neoplasm typically found on the sun-exposed areas of the head or neck of the elderly. OBJECTIVE: We report a case of localized cutaneous metastases attributed to an atypical fibroxanthoma. METHODS: A case report and a review of the literature of metastasizing atypical fibroxanthoma are given. RESULTS: Mohs micrographic surgery was used to treat all skin lesions and currently the patient has no suspicious lesions. CONCLUSION: Metastases attributed to atypical fibroxanthoma are rare, and many prior reports may have actually been malignant fibrous histiocytoma, spindle cell melanoma, or spindle cell squamous carcinoma. Tumor depth, vascular invasion, and cutaneous tumor recurrence appear to increase risk for metastasis.

Aged↗

Sarcoidosis.

Sarcoidosis is a systemic granulomatous disease of unknown cause that most commonly affects the lungs, lymph nodes, skin, eyes, spleen, bone, and glandular tissue. The diagnosis is made when characteristic histologic findings are demonstrated and other granulomatous processes are excluded. It can be an acute or chronic debilitating disease, but in patients with acute disease the process can be self-limited. Multiple therapeutic options have been described both for the cutaneous and systemic lesions of sarcoidosis. Steroids, however, remain the cornerstone of therapy.

Diagnosis, Differential↗