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Biomedical subjects

T J Liao

Publications and source records attributed to T J Liao.

4 recordsLinked to original sources

Transient decrease in skin resistance response and level at the deh-chi stage caused by manual acupuncture.

Deh-chi is described as a kind of soreness, numbness, or heavy swelling in deep tissues during manual acupuncture. This finding is important in acupuncture therapy, although the mechanism of this phenomenon remains unclear. Skin resistance response (SRR) and skin resistance level (SRL) are expressed as a component of alternating current and direct current changes in electrodermal activity (EDA) respectively. In the present study, we recorded SRR and SRL, skin blood flow and perspiration simultaneously in an attempt to determine the relationship between skin sympathetic nerve activity and EDA at the deh-chi stage. We found that SRR, SRL and skin blood flow decrease, and that perspiration increases transiently at the deh-chi stage. Our findings indicate that manual acupuncture causes an increase in vasomotor and sudomotor activities, a decrease in skin blood flow, and increased perspiration. These SRR and SRL recordings may be taken as an indicator of deh-chi.

Acupuncture Points↗

The variation of action potential and impedance in human skeletal muscle during voluntary contraction.

We used an insulated acupuncture needle to deliver a 20 kHz alternative current to detect the changes on the electromyogram (EMG) and deep muscle impedance. We found that impedance increased (with a duration of 224.1 +/- 75.3 msec) and then decreased (with a duration of 293.4 +/- 97.3 msec) after motor unit action potential (MUAP) firing during isometric voluntary contraction (VC) of the tibialis anterior muscle (TAM). We divided the positive peak into pattern I (with a latency range of > or = 30 msec and < or = 75 msec) and pattern II (with a latency range of > 75 msec and < or = 140 msec). These patterns of change corresponded to the contraction times of tension caused by the electrical stimulation and VC. These impedance changes may be caused by a change in the extracellular and intracellular fractions, and may reflect the variance of tension intensity in the muscle tissue.

Action Potentials↗

[The effect of acute and persistent ocular hypertension on ultrastructure in rabbit tissues of anterior chamber angle].

Sclero-circular compression operation was performed on 20 unilateral rabbit eyes to make a model of intraocular hypertension which persisted for 3 days, 1, 3 and 4 weeks respectively in 4 groups of rabbits and another 4 rabbits were used as normal controls. The trabecular meshwork and aqueous plexus of the experimental rabbits' eyes were examined under transmission electron microscope on various post-operative days: 3 days, 1, 3 and 4 weeks. It was discovered that the corneo-scleral and uveal trabecular meshworks were obviously distended and their core collagenous and elastoid fibers were hyperplastic, the phenomenon being more marked with the prolongation of the duration of the intraocular hypertension. Many endothelial cells were detached from the trabecular cords and freely located in the intertrabecular spaces. Persistent hyperplasia of collagenous fibers and accumulation of extracellular plague materials occurred in the endothelial meshwork, leading to its compactness. The giant vacuoles in the endothelial cells lining the inner wall of the canal of aqueous plexus were gradually decreased in number and the cytoplasm of the cells became attenuated and some fenestrations appeared. The results show that the main site of the resistance of the aqueous outflow occurring during intraocular hypertension is at endothelial meshwork and the above experimental morphological changes are quite similar to those of glaucoma patients.

Animals↗

The effect of acupuncture stimulation of the middle latency auditory evoked potential.

The effects of acupuncture stimulation (AS) on the middle latency auditory evoked potentials (MLAEPs) were studied in 19 normal male volunteers. Scalp recordings were made from 21 points (including Cz) and posterior auricular muscle (PAM) electrodes referenced to the linked mastoid. Four components of MLAEPs (Po, Na, Pa and Nb) and two components of PAM reflex (N12 and P17) were statistically analyzed for changes in latency and amplitude. Wave phase of Po and Na reversed to N12 and P17, respectively, and the peak-to-peak amplitude of Po-Na, Na-Pa, Pa-Nb and N12-P17 showed a marked increase during AS to the ipsilateral side whereas no change in latency was detected. Each component's isovoltage topographic maps and dipole locations were calculated to be near both PAM (Po and Na) and temporal positions (Pa and Nb) during AS. These data showed that AS can promote MLAEPs activity and these signals (Po and Na) may originate from increased activity in N12 and P17 of the PAM reflex, respectively, and that the auditory cortex of the temporal gyrus is the generator substrate of Pa and Nb.

Acoustic Stimulation↗