Torsades de pointes complicating treatment with terfenadine.
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Benzhydryl Compounds↗
Biomedical subjects
T J MacConnell
Publications and source records attributed to T J MacConnell.
Left ventricular hypertrophy.
Left ventricular hypertrophy (LVH) may be physiological or pathological. Only pathological LVH has been shown to be a risk factor for cardiovascular events. LVH may not be homogeneous. It seems to progress from muscle hypertrophy to eventual cell death and myocardial fibrosis. Potential for reversal of LVH may therefore depend on the stage at which it has been attempted. An interaction between LVH and serum potassium levels could have important therapeutic implications, particularly with regard to the use of thiazide diuretics as long-term treatment for hypertension.
Animals↗
Alcohol intoxication and alcoholism in acute male medical admissions.
In order to assess alcohol related morbidity in male hospital patients we studied all acute male admissions over a period of three months. 9.3% of patients were found to have detectable alcohol on admission (level greater than 4 mmol/l). A total of 28.3% of admissions were judged to be alcoholic by questionnaire (Michigan Alcohol Screening Test). These results suggest that acute intoxication in male hospital admissions is not as common as previously recorded. The prevalence of alcoholism, however, was disturbingly high and has significant implications for in-patient management.
Adolescent↗