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Biomedical subjects

T J Tarnay

Publications and source records attributed to T J Tarnay.

At least 19 recordsLinked to original sources

An alternative method for repair of partial anomalous pulmonary venous connection to the superior vena cava.

The surgical management of 15 patients with partial anomalous pulmonary venous connection (PAPVC) to the high superior vena cava (SVC) is described. This new technique redirects the anomalous pulmonary venous flow into the left atrium through the cardiac end of the SVC, transected and oversewn above the anomalous pulmonary vein or veins, by coaptation of the atrial septal defect (or of the surgically created septal defect in patients with an intact atrial septum) to the intracardiac orifice of the SVC. Normal SVC-right atrial flow is reconstituted by atriocavoplasty to the cephalad portion of the transected SVC. A 31-year-old woman with severe pulmonary hypertension died early in the series; this was the only death. Surviving patients enjoy full activity. Except for one symptomatic SVC obstruction due to technical error (since relieved), this technique has achieved total correction of these congenital defects with marked reduction in the undesirable postoperative sequelae often associated with other methods of repair.

Adolescent

Long-term survival with ventricular pacemaking: initial 15-year experience.

The records of all 380 adult patients receiving cardiac pacemakers at West Virginia University in the 15-year period ending January 1, 1977, were reviewed. The five-year survival rate was 58 per cent and the 10 year, 38 per cent with a median survival of 74 months. Life expectancy approached life-table curves if the mortality during the initial year was ignored. Although the younger patients lived the longest, their expected survival was reduced more than in the older patients. The need for a pacemaker in a young person implies serious life-shortening consequences. Unlike reports in the literature, patients with sinoatrial disease fared worse than those with A-V block.

Actuarial Analysis

Coarctation of the thoracic aorta: an 18-year experience.

From 1960 to 1978, 80 patients from 2 weeks to 49 years of age underwent operations for coarctation of the aorta. Twelve patients were under 3 months old, and 68 were older. All of the infants presented with congestive heart failure and multiple cardiac defects. In the older patients, hypertension was the most common presenting symptom; 14 were asymptomatic. All patients under 3 months old received primary correction. Seven (58%) died of complications associated with other cardiac anomalies. In the older group, there was 59 primary reconstructions, six interposition grafts, and three other procedures. There were two deaths in this group. There were three re-explorations, two for bleeding and one for false aneurysm at the suture line. Seven older patients exhibited paradoxical hypertension: three developed abdominal symptoms and two required laparotomy. Three patients originally operated on during infancy developed recurrent coarctation with reoperation in two. Nine of the older patients had chronic hypertension, all of whom were operated on after age 15. Surgical correction of coarctation in infants carries a high mortality rate secondary to associated defects. The operative mortality rate in older patients is minimal, and correction should be undertaken early to prevent the long-standing complications of hypertension.

Adolescent

Pneumatic calf compression, fibrinolysis, and the prevention of deep venous thrombosis.

In a previous pilot study that did not reach statistical significance, intermittent single-leg pneumatic compression appeared effective in reducing the incidence of calf vein thrombosis not only in the pumped calf but also in the unpumped leg in 37 patients, using the 125I-fibrinogen (Abbott Laboratories) technique. The present study was undertaken to investigate mechanical induction of local and systemic fibrinolysis. The euglobulin lysis time in the arm venous effluent was determined in five volunteers before and after unilateral arm compression for 1/2 hour. Shortening averaged 19% (not significant). The experiment was repeated using bilateral calf-length boots with femoral vein sampling. Euglobulin lysis decreased 22% (P < 0.001). To uncover possible systemic effects, the protocol was altered using calf boots with sampling from the arm. The euglobulin lysis diminished 6% in 57 volunteers (P < 0.001). In 27 others the effects of thigh-length and calf-length boots were compared. In half, pumping with a short boot was undertaken first, and in the remainder, the long boot was applied initially. One-half hour of pumping was followed by 1/2 hour of rest. Immediately afterward the second period of pumping took place and continued for 1/2 hour. A total of four arm vein samples were obtained, one before and after each pumping period. Although, in retrospect, the 1/2-hour rest period was inadequate to permit the subjects to return to basal conditions, statistically significant decreases in euglobin lysis time (P = 0.05) occurred with the long boots. This study shows intermittent calf compression increases fibrinolytic potential locally and this effect can be demonstrated systemically. The greater the volume of tissue compressed, the greater the response. The efficacy of intermittent venous compression in reducing the incidence of deep venous thrombosis may be due, in part, to localized induction of fibrinolysis.

Adult

Upper limb ischemia resulting from arterial thromboembolism.

Acute ischemia of the upper limb is commonly caused by trauma and embolic arterial occlusion. However, primary atherosclerotic thrombosis is found infrequently and concern regarding its incidence, recognition, and treatment prompted a review of our clinical experience. Of 36 patients with acute ischemia of the upper limb, 17 (47.2 per cent) had embolic occlusion, 9 (25 per cent) iatrogenic thrombosis in the brachial artery, and 10 (27.8 per cent) primary arterial thrombosis. Of the total group, noncardiac arterial emboli (two patients) and primary atherosclerotic thrombosis (six patients) accounted for 8 of 36 (22.2 per cent) ischemic limbs. Including 2 additional patients who had atherosclerotic thrombosis associated with trauma, the total number represented 10 of 36 (27.8 per cent). An aggressive approach to the undiagnosed patient with acute ischemia of the upper limb is warranted, including the use of arteriography in most cases. In patients with iatrogenic thrombosis in the brachial artery, we believe that the routine use of intraoperative arteriograms may improve the operative results.

Adolescent

Effectiveness of elastic stocking decompression.

The compression effectiveness of the five leading brands of antiembolism stockings was compared and related to criteria previously described (pressure gradient diminishing from 18 mm Hg at the ankle to 8 mm Hg at the thigh). Tests were conducted using a standard leg form in common use within the hosiery industry, fitted with specially developed sensors. All of the stockings achieved pressures higher than recommended-some substantially. Elastic stockings from two manufacturers demonstrated tourniquet effects at the calf. Several brands ceased to preserve a continuously diminishing pressure gradient above the knee. Deviation of leg diameter from standard geometry was accompanied by a substantial increase (decrease) in pressure with increasing (decreasing) girth. Reproducibility of pressure effects produced by identical-sized stockings varied among the brands tested.

Adult