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Biomedical subjects

T J van de Merwe

Publications and source records attributed to T J van de Merwe.

7 recordsLinked to original sources
PubMed1984

A double-blind non-crossover placebo-controlled study between group comparison of trazodone and amitriptyline on cardiovascular function in major depressive disorder.

The cardiovascular effects of trazodone ( TZD ), amitriptyline (AMT) and placebo were studied in out-patients with major depression. AMT was shown to have the expected effects on the electrocardiograph and on systolic time intervals consistent with its proven anticholinergic and quinidine-like properties. TZD , in contrast, had no quinidine-like effects and minor effects on systolic time intervals. However, it was not without any cardiovascular effects. Although TZD was shown to be a safer preparation than the reference drug AMT, long-term monitoring is needed to explain the minor effect on heart rate and T wave changes.

Adult↗
PubMed1983

[Anorexia nervosa].

Explore the source record for details and available documents.

Anorexia Nervosa↗
PubMed1981

[A detoxification unit of adult black males with a standard treatment regimen].

During the period January-June 1975 a relatively high death rate (8,29%; 33 out of 398 patients) was noted in young Black males clinically diagnosed as suffering from toxic psychosis caused by alcohol. Pellagra, malnutrition and pneumonia were complicating factors. After a trial period of 6 months, a detoxification unit was established for these high-risk patients. A total of 615 high-risk patients (15,12%; 615 out of 4 065) was treated with a standardized regimen during the 2 1/2-year period June 1975 - December 1977. Thirty-three out of 615 patients (5,36%) died during this period, 1,57% of the total number with toxic psychosis due to alcohol abuse (33 out of 4065) over a 2 1/2-year period. This rate compares favourably with the average reported rate of 10 - 15%. Effective treatment of high-risk alcohol-induced states reduces the complications and death rate.

Adult↗
PubMed1980

[Aspects of suicide].

A review of relevant publications with reference to epidemiological data and their application to predictive profiles of at-risk populations regarding suicide and attempted suicide is given. It is indicated that suicide and parasuicide are to be seen as sociocultural problems with a complexity of contributing factors. Conscious and subconscious motives play a part within a psycho-existential continuum with intrapsychic, interpersonal, biological, psychological and social components. This spectrum of individualized components and the social impact of the deed present the clinician with a psychiatric emergency for which he must be adequately equipped. Management based on a team approach is delineated.

Adolescent↗