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T Joly

Publications and source records attributed to T Joly.

4 recordsLinked to original sources
PubMed2005

[Follicular morphology after ovarian cortex cryopreservation in the rabbit doe(Oryctolagus cuniculus)].

OBJECTIVE: To compare the effects of two cryoprotective agents (DMSO and 1,2-PROH) used at two concentrations (1,5 and 2 M) on the morphology of small ovarian cortex follicles in doe. MATERIALS AND METHODS: Ovarian cortexes (n=40) were frozen in TCM199+10% FCS medium added to 1.5 or 2 M of DMSO or 1,2-PROH. Two controls were realized (fresh and frozen without cryoprotectant). The equilibration in cryoprotective solutions before freezing, and the elimination of the cryoprotective agents after thawing, was performed step by step. The effects induced by cryopreservation were evaluated by histological examination. RESULTS: Fresh ovarian tissue showed 68.6% of intact follicles. After freezing, only 1.5 M of 1,2-PROH preserved 48.0% of normal follicles, with no significant difference compared to the fresh control. The proportion of follicles without morphological defect observed after cryopreservation with DMSO was significantly reduced (respectively 28.8 and 34.8% for 1,5 and 2 M of DMSO). DISCUSSION AND CONCLUSIONS: Our results suggest that 1,2-PROH is a more effective cryoprotectant than DMSO, for the cryopreservation of doe ovarian cortex. These results differ from those that were obtained for other species, credibly because of a higher fragility of the ovarian tissue of the doe. Nevertheless, this species is an interesting animal model which allows rapid results after cryopreserved ovarian tissue graft.

Animals↗
PubMed2000

[Macular functions in professional divers].

PURPOSE: Air diving is frequently practiced by professionals or sportsmen. Controversial data exist in the literature on the existence of retinal abnormalities in divers. PATIENTS AND METHODS: 18 divers (aged: 27-58y) who dived around 2000 times in their life were studied: half of them dived only with air while the others used an O2-enriched gas mixture (40 to 60%). None of them had presented a bend (decompression sickness). Visual acuity and ocular fundus examination have been explored. A quantification of color vision and central visual field, so as a fluorescein angiography have been performed. RESULTS: No alteration of visual acuity was noted; abnormalities in the color vision and the visual field are reported; however the angiographic lesions described in the literature have not been observed. DISCUSSION: The alterations of color vision were quite severe but not very frequent. No correlation was found with any characteristics or type of diving. CONCLUSION: These observations are comforting for sportive divers who do not dive very often nor very deep but an individual predisposition is suspected.

Adult↗
PubMed1978

[3 recent cases of Noonan's syndrome].

In the present state of our knowledge of cytogenetics, it seems logical to distinguish Noonan's syndrome from Turner's syndrome, thanks to the following arguments: Althought there are minor differences in the morphotype, the small size and the mental retardation are the same in both cases. However there are two lines of evidence: The first, inconstant, concerns the lesser intensity of the gonad changes, especially in the female sex, explaining the relative frequency of the familial forms of the syndrome, of Noonan, which are then trasmitted as autosomic dominants with variable penetrance. The second, constant and formal until now, concern the chromosome abnormalities. Present in Turner's syndrome, which they help to define in both sexes, they are always absent in Noonan's syndrome, in boys as in girls.

Child↗