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T K Pilgram

Publications and source records attributed to T K Pilgram.

78 records · Page 5Linked to original sources
PubMed1989

Craniosynostosis: diagnostic value of three-dimensional CT reconstruction.

Three-dimensional computed tomography (CT) has an important role in determining the presence and extent of congenital and acquired craniofacial deformities. The authors compared the sensitivity and specificity of three-dimensional CT in the detection and characterization of craniosynostosis with that of planar CT and skull radiography. Eighty-two patients with isolated and syndromal synostoses were imaged with CT and three-dimensional CT, and 42 with skull radiography. Three-dimensional CT scan processing was performed by shaded-surface reconstruction, volumetric, and depth-coded methods. Two trained observers read each scan series in a blinded fashion. Diagnostic utility of the images was determined with receiver operating characteristic analysis. The observers ranked three-dimensional shaded images higher than the other types, with three-dimensional volumetric images second and three-dimensional surface images ranked third. Results of this study demonstrate that three-dimensional shaded-surface reconstruction from CT scans is superior to conventional plain radiographs and CT scans in diagnosing craniosynostosis.

Adolescent↗
PubMed1989

Craniosynostosis: image quality, confidence, and correctness in diagnosis.

The authors used the diagnosis of craniosynostosis to compare subjective evaluation of image quality with objective diagnostic utility. They studied in detail the responses of one observer, who read plain radiographs, computed tomographic (CT) scans, and three-dimensional reconstructions of CT scans (obtained with three different methods) for 82 patients with this diagnosis. The observer rated image quality and certainty in diagnosis made from each image. Subjective and objective performances were found to be strongly linked. High-quality images served as the basis for more accurate diagnoses than low-quality images. The increase in diagnostic performance results primarily from increased specificity, a fact that suggests that specificity and the concomitant diagnosis of normalcy are the focus of attention when image quality is evaluated.

Adolescent↗
PubMedDate not supplied

MR imaging of Crohn disease: use of perflubron as a gastrointestinal contrast agent.

This study was undertaken to evaluate the use of perflubron (perfluorooctylbromide) as an oral contrast agent for magnetic resonance (MR) imaging of patients with Crohn disease. MR examinations were performed before and after perflubron administration in 12 patients with documented Crohn disease. Glucagon was administered intramuscularly before the post-perflubron examinations. Each patient also underwent abdominal computed tomography within 48 hours of MR imaging. The imaging studies were analyzed for effectiveness of bowel marking with oral contrast agent, clarity bowel wall visualization, and presence of bowel wall thickening and extraluminal manifestations of Crohn disease such as abscess or fistula formation. Analysis of the imaging studies showed effective marking of the bowel with perflubron and improved bowel wall visualization on postcontrast MR images. Detection of bowel wall thickening and extraluminal complications of Crohn disease was not significantly improved on postcontrast MR images. The authors conclude that perflubron administration effectively marked the bowel and increased the clarity of bowel wall visualization but did not significantly increase the detection of abnormalities related to Crohn disease in the study population.

Adult↗
PubMedDate not supplied

Diagnostic performance of CT, MPR and 3DCT imaging in maxillofacial trauma.

CT imaging of complex maxillofacial fractures is common practice now, but the relative diagnostic value of spiral computed tomography (CT), multiplanar reformations (MPR), and three-dimensional (3D) reconstructions in evaluating maxillofacial fractures is not established with independent validation of correct diagnosis. We studied these modalities and measured their diagnostic value in a carefully controlled observer based rated response experiment. Multiple fractures were created by blunt experimental trauma in nine adult cadaver heads (five males, four females). Spiral CT scans were performed on all specimens before (control) and after trauma. Axial slices (CT), sagittal and coronal multiplanar reconstructions (MPR), and 3D volumetric reconstructions views were generated. Truth was determined by defleshing the specimens and direct inspection of the traumatized skull. Three expert readers separately interpreted CT, MPR and 3D film hard copy images presented in random order blinded to patient identification or experimental conditions. We measured the time to diagnose each case as recorded by a monitor who was present while evaluations were performed. Twenty-eight facial regions were evaluated using rated response and free response illustrative formats. Each region was considered separately. Sensitivity and specificity were calculated to measure observer performance. We found that 3D and CT had a similar performance in fracture detection and both were markedly better than MPR. For free response illustrative data, CT correctly identified 10% more orbital fractures than 3D, and approximately 10% fewer zygomatic fractures. Fracture localization was best with 3D. Reader confidence was highest with CT, but assessment time was faster with 3D. We conclude that CT and 3D are comparable in detecting midfacial fractures and both are superior to MPR. 3D reconstructions are superior for localization of complex fractures involving multiple planes.

Aged↗
PubMedDate not supplied

Effect of intraarterial papaverine on cerebral circulation time.

PURPOSE: To measure the mean cerebral circulation time (CCT) in patients with symptomatic vasospasm stemming from subarachnoid hemorrhage and to determine any change after papaverine treatment. METHODS: We studied 27 patients who received intraarterial papaverine from November 1992 to August 1995 to determine the CCT in 59 carotid territories. CCT was measured from the first image in which contrast was seen above the supraclinoid internal carotid artery to the peak filling of parietal cortical veins. Angiograms at the time of presentation were examined in 19 of the 27 patients. A control population of 19 patients (30 carotid territories) was also studied. RESULTS: The mean CCT on presentation was 6.8 seconds +/- 1.1. The prepapaverine mean CCT was 6.1 seconds +/- 1.2. The immediate postpapaverine mean CCT was 3.8 seconds +/- 0.8. CCT decreased in 58 of 59 territories treated with papaverine; the mean change was -35.7%. In eight of these patients, CCT rose on the following day to 6.1 seconds +/- 1.1. In the control group, mean CCT was 5.9 seconds +/- 0.8. The mean CCT in patients with subarachnoid hemorrhage was slightly prolonged on presentation relative to that in control subjects. CONCLUSION: Intraarterial papaverine produces a consistent decrease in CCT in patients with vasospasm.

Adult↗