T K Shnitka — Page 3 | PubMed Health

PubMedDate not supplied

Exfoliative cytology of clear-cell sarcoma metastases in pleural fluid.

Two cases of clear-cell sarcoma arising from the leg with widespread metastasis were reported. Exfoliated tumor cells in pleural effusions were round, oval, and slightly pleomorphic. They were seen singly or in clusters of variable size with marked cellular cohesiveness and molding. Their cytoplasm was well-defined, clear, or finely granular, and contained S-100 protein and periodic acid-Schiff positive material that was digestible by diastase. Tumor-cell nuclei were round and hyperchromatic with irregular chromatin clumping, and showed conspicuous nucleoli.

Adult↗

PubMedDate not supplied

Aspiration biopsy cytology of adenocarcinoid tumor of the bronchial tree.

Aspirated material from two cases of histologically and ultrastructurally confirmed adenocarcinoid tumor of the lung was evaluated. In one case, columnar and cuboidal cells with ill-defined cytoplasm and round or oval nuclei were seen in large sheets and syncytiumlike clusters with focal glandular arrangement. In the other case, spindle-shaped and columnar cells with ovoid nuclei and ill-defined cytoplasm were seen singly and in loose clusters. Fragments of tumor epithelium with nuclei arranged in pseudo-stratified pattern were noted. Staining of tumor cells by the Grimelius technique demonstrated numerous intracytoplasmic brown-black granules. The cytologic differential diagnosis between adenocarcinoid tumor and other primary and metastatic adenocarcinomas of the lung is briefly discussed.

Biopsy, Needle↗