PubMed Health⌕ Search

Biomedical subjects

T Kanra

Publications and source records attributed to T Kanra.

At least 19 recordsLinked to original sources
PubMed2005

Whole blood versus red cells and plasma for exchange transfusion in ABO haemolytic disease.

Records of 381 neonates who underwent exchange transfusion (ET) due to ABO haemolytic disease at the Division of Neonatology of Hacettepe University, Ankara, Turkey, between January 1977 and December 2003 were reviewed. Records were kept for the type of blood used in ET, the number of ETs for each infant, adverse event attributable to ET and bilirubin levels before, and 4 and 8 h after each ET. Of 381 infants, 300 were transfused with whole blood, whereas 81 infants were transfused with O red cells suspended in A or B plasma. The re-exchange rate was higher in the whole blood group, compared with the erythrocyte and plasma group. Use of erythrocyte and plasma provided 30% reduction in the number of ETs per patient. Eight hours after the first ET, mean bilirubin levels were 84% of the pre-exchange values in the whole blood group and 73% of the pre-exchange values in the erythrocyte and plasma group (P = 0.001). As the use of O group red cells re-suspended in AB plasma decreased the re-exchange risk compared with O group whole blood, we suggest the use of O red cells re-suspended in AB plasma for the ET in cases of ABO haemolytic disease.

ABO Blood-Group System↗
PubMed1994

Chronic autoimmune hemolytic anemia in children: a report of four patients.

Four children, ages seven to ten years, with direct antiglobulin test (DAT)-positive chronic hemolytic anemia are presented. The patients were followed for 3 to 10 years. Autoantibody against red cell antigens was nonspecific IgG type in all of the patients. In one of the four patients, anemia was associated with splenomegaly and jaundice. In this patient, the third component of the complement was also detected on the red cell surface. In one patient, serum IgA deficiency and frequent pulmonary infections were associated with the disease. This patient developed rheumatoid arthritis five years after diagnosis of hemolytic anemia. The third patient initially had thrombocytopenia subsequently developed DAT-positive hemolytic anemia, vitiligo and alopecia without any evidence of serologic changes suggestive of collagen vascular disorders. In these three patients, partial response was obtained with steroid therapy. The fourth patient developed DAT-positive hemolytic anemia twice during the five year follow-up period. Anemia resolved completely with steroid therapy in two months during the first episode, and in five months in the second. Generalized and peripheral lymphadenopathies which developed at the time of the second hemolytic anemia episode have persisted for the last three years. Administration of cyclosporine in two of the four patients did not result in any amelioration of the symptoms.

Anemia, Hemolytic, Autoimmune↗
PubMed1978

Rifampicin-dependent antibodies in a patient with hepatorenal failure.

We report a case of hepatorenal failure complicating rifampicin administration in which rifampicin-dependent antibodies were demonstrated. Hepatorenal failure during rifampicin treatment has been reported before but in none of the previous cases were rifampicin-dependent antibodies described.

Acute Kidney Injury↗
PubMed1976

Incidence and distribution of hepatitis Bs-antigen in Turkey.

The sera of 3,363 healthy people from different regions of Turkey were investigated for the presence of hepatitis Bs-antigen. Agar-gel double diffusion technique was employed for the demonstration of this antigen. In 101 persons than antigen was found to be present, giving an incidence of 3% for hepatitis Bs-antigen in Turkey.

Adolescent↗
PubMedDate not supplied

Rh blood group system in Turkey.

Because of the absence of original data concerning the Rh blood group system in Turkey, for the benefit of researchers interested in the human blood groups field, serological results obtained in Hacettepe University Hospitals' Blood Center between 1980 and 1996 have been evaluated for the first time in this paper. During the study, 581,606 people were evaluated for Rho (D) positivity and negativity. In addition, 5,600 people from different parts of Turkey were screened for the five major antigens (D, C, E, c, e) of the Rh blood group system and, according to the results, various gene frequencies and most likely genotypes were calculated. Results clearly show that the Rh blood group system in Turkey is completely, in line with that of the Caucasians.

Gene Frequency↗
PubMedDate not supplied

Autoimmune hemolytic anemia with warm antibodies in children: retrospective analysis of 51 cases.

In this paper, research based on 51 children with a positive antiglobulin test is presented. Eighteen of the children had acute anemia and 33 had chronic anemia. Two clinical patterns were distinguished: an acute transient type and a prolonged chronic type. Corticosteroid therapy was effective in all acute cases but its results were variable in the chronic cases. The acute form was more frequent in young children, while chronic autoimmune hemolytic anemia (AIHA) occurred mainly among children at puberty. In the chronic form of the disease, it was sometimes necessary to add immunosuppressive drugs and in two cases to perform a splenectomy.

Acute Disease↗
PubMedDate not supplied

Acute hemolytic anemia caused by irregular rifampicin therapy.

Acute hemolytic anemia characterized by vomiting, diarrhea, vertigo, lumbar pain pallor and high fever due to an irregular and high dose of rifampicin is described in a 13-year-old girl during her treatment for tuberculosis. The presence of rifampicin-dependent antibodies was identified by special tests.

Adolescent↗