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Biomedical subjects

T Karwan

Publications and source records attributed to T Karwan.

10 recordsLinked to original sources

Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations.

Distribution of calcium and phosphorus was investigated with quantitative and qualitative methods in teeth of rats chronically treated with low doses of corticosteroids for 3 generations. In animals from 2nd and 3rd generation, scanning electron microscopy revealed focal lesions in enamel and dentin. The disturbances of the mineral metabolism in teeth of corticosteroid-treated rats were also reflected by abnormal calcium and phosphorus content in enamel and dentin, as assessed by X-ray microanalysis.

Adrenal Cortex Hormones

[Deciduous teeth with fluorosis from a morphological and microanalytical point of view].

Deciduous teeth with enamel fluorosis obtained from a 7 year-old child and normal deciduous teeth were studied by light microscopy and X-ray microanalysis. In the fluorotic teeth, altered architecture of enamel prisms and marked damage of enamel were observed. X-ray microanalysis revealed disturbances in the mineral metabolism of the fluorotic tooth tissues: as compared with normal teeth, an increase in calcium, phosphorus and magnesium content as well as lowered calcium/phosphorus ratio were found in the enamel prisms, interprismatic substance, dentinal tubules and intertubular dentin.

Child

Structural and microanalytical changes in dentition after radiotherapy applied in cases of tumour in the oral cavity region.

Morphological observations by means of the scanning electron and optical microscopes as well as microanalytical qualitative and quantitative tests concerning content and distribution of calcium, phosphorus and magnesium in the teeth being in irradiation field were made in patients treated for larynx cancer by methods of radiotherapy. The teeth enamel was in some places thinner and in some others it was lacking. The characteristic defects took place in the form of notches, cracks and of superficial destruction. In X-ray microanalyser the enamel showed some features of demineralization. In dentine, features of demineralization and on the other hand features of remineralization were seen. The root dentin, in which destructive processes but also reparation processes developed by root cement could be seen, was rather characteristic. Clear structural changes and disturbances of mineralization in hard tooth tissues being under therapeutic X-ray irradiation were observed.

Adult

Morphology and microanalysis of teeth in scleroderma.

The studies were carried out on teeth extracted for stomatological reasons in the persons with generalized scleroderma. The studies included: morphologic examination of the longitudinal and cross-ground sections in the light and scanning microscope, and microanalytic examination of the longitudinal halves of the teeth in the X-ray microprobe. In the course of scleroderma morphological changes of the mesenchymal origin occurred in the teeth hard tissues. The deviation in the calcium and phosphorus contents was relatively significant and an absence of magnesium in the dentine and distinct dećrease in the calcium-phosphorus ratio were observed.

Calcium

Quantitative, qualitative and topographic distribution of lead, zinc, iron and copper in hard teeth tissues.

The objectives of the paper included a quantitative evaluation qualitative and topographic distribution of four microelements, namely lead, zinc, iron and copper, within enamel prisms, interprismatic region, tubular dentine, and intertubular dentine. The studies were carried out with the use of an X-ray microanalyser and an electron scanning microscope. The values of lead, zinc, iron and copper were higher in the enamel. Topographic curves for all the elements were similar within the enamel and dentin, characterized by unevenly distributed flat zero segments along with several peaks of diversified amplitude, being somewhat denser in the enamel. Qualitative distribution of the elements was also similar, and slightly denser within the enamel, the grains being unevenly scattered.

Animals