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Biomedical subjects

T Kazui

Publications and source records attributed to T Kazui.

At least 181 records · Page 10Linked to original sources

Surgical treatment of aneurysms of the thoracic aorta with the aid of partial cardiopulmonary bypass: an analysis of 95 patients.

We retrospectively evaluated the surgical results in 95 patients with aneurysm of the thoracic aorta who were surgically treated using partial cardiopulmonary bypass (CPB) as an adjunctive method during the past 10 years. The cause of the aneurysm was atherosclerosis in 52% and dissection in 41%. Fifty-eight percent of the patients had an aneurysm of the entire descending thoracic aorta and 14 of these patients had a thoracoabdominal aneurysm. Emergency operation was performed in 16 patients (17%). There were 14 early deaths (14.7%) within one month after operation. Postoperative complications included renal dysfunction, partial paraplegia, and hemorrhage. Renal dysfunction occurred in 7 (7.8%) of the operative survivors; 2 of the 7 required hemodialysis. Partial paraplegia was observed in 2 patients undergoing total replacement of the thoracoabdominal aorta. Neither renal dysfunction nor paraplegia was related to the duration of aortic cross-clamping. Postoperative hemorrhage necessitating reopening of the chest occurred in 8 (8.9%) of the operative survivors. Partial CPB is useful in reducing the incidence of postoperative complications among patients undergoing aortic cross-clamping for a long period.

Aortic Dissection↗

Clinical evaluation of the Omniscience aortic disc valve prosthesis.

The clinical results and hemodynamics were evaluated in 100 cases of aortic valve replacement, using the Omniscience valve, in the period December 1980 through 1984. Late survival rate, clinical improvement and cardiac and prosthetic valve performance were acceptably satisfactory. The overall incidence of thromboembolism was 4.7%/patient year. The opening angle of the disc was less than 60 degrees in 18% of the studied cases. Further investigations are required to determine if such results were related to the valve structure or to some cause in the recipient. Assessment of the durability of the Ominiscience cardiac valve prosthesis must await the results of long-term observation.

Adolescent↗

[A case of aneurysmal dilatation of a saphenous vein graft for subclavian aneurysm in a patient with Behçet disease].

The autogenous saphenous vein is the preferred conduit for repair of occluded arteries in the limb and coronary arteries. The aneurysmal dilatation of the vein graft is a unusual complication in the long-term period. A case of aneurysmal formation of the vein graft for the subclavian aneurysm 5 years after grafting with classic Behçet disease was reported. The etiology of this rare complication and the special surgical problem were also discussed.

Adult↗

Long-term management of patients with cardiac valve prostheses.

Marked improvements have been achieved in the results of valve replacement due to recent developments in cardiac valve prostheses, surgical procedures, myocardial protection methods, and supportive techniques. Since 1974, the aortic valve has been replaced with mechanical valves and the mitral valve with biological valves at our institution. During a cumulative follow-up of 1024 patient-years after 306 valve replacements (126 AVR, 148 MVR and 32 AVR + MVR), the 10-year survival rates were 88% for AVR, 72.6% for MVR and 77.5% for AVR + MVR. The cardiac function of 90% of the survivors was evaluated as Class I or II according to NYHA Functional Classification. As for valve-related postoperative complications, thromboembolism was observed in 2.3%/pt-yr, hemorrhage in 0.5%/pt-yr, prosthetic valve endocarditis in 1.3%/pt-yr, perivalvular regurgitation in 1.3%/pt-yr and valve malfunction in 1.1%/pt-yr. Of the causes of late deaths, 62.5% were related to valve complications. Re-replacement of the prosthesis was necessary in 17 patients due to valve-related complications, and early death occurred in 1 (5.9%) of these 17. While cardiac valve replacement contributes to improvements in the quality of the patients' long-term postoperative life, currently employed artificial valves are still not ideal with regard to their materials and design, and re-replacement may become necessary in the late postoperative period. Therefore, in addition to selection of the appropriate valve prosthesis for different disorders and optimal prevention of valve-related complications, early diagnosis by non-invasive techniques and early treatment of these complications if they have occurred are of particular importance for the long-term management of patients following cardiac valve replacement.

Activities of Daily Living↗