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Biomedical subjects

T Kitano

Publications and source records attributed to T Kitano.

At least 37 records · Page 2Linked to original sources
PubMed1989

Iron in cicatrix and abnormal CT findings in a patient with posttraumatic epilepsy.

A 33-year-old male patient showed increasing frequency of seizures 12 years after a blunt head injury. From findings of x-ray computed tomography, the lesion was thought to be a benign glioma. Removal of the lesion was performed with the guidance of electrocorticography. Histological diagnosis was gliotic scar with calcification. Diffuse iron particles were detected in layers II-V of the cortex by hematoxylin and Berlin-Blue stain. These findings suggest progressing traumatic epilepsy which may be explained by the mechanism of Willmore's model.

Adult↗
PubMed1988

A large inferior mesenteric-caval shunt via the internal iliac vein.

A large portosystemic shunt between the inferior mesenteric vein and the right internal iliac vein in a 28-yr-old non-cirrhotic man is presented. This collateral was discovered by ultrasound done as a screening examination for gastrointestinal bleeding. The direct communication of the inferior mesenteric vein with the internal iliac vein was demonstrated by computed tomography and percutaneous transhepatic portography. Surgical ligation of the collateral, performed to prevent future portosystemic encephalopathy, resulted in reduction of serum ammonia level and cessation of long-standing hemorrhoidal bleeding.

Adult↗
PubMed1988

Role of hypovolemia in dialysis-induced hypotension.

Blood volume was measured continuously during hemodialysis using the authors' hematocrit continuous measurement system in an attempt to determine any relationship between dialysis-induced hypotension with acute onset and blood volume. Hypotension resulted approximately 3 h into dialysis in the present study. This point in time was that at which blood volume was more than 5% above the minimum level during the dialysis treatment, and in some patients it was more than 10% over the minimum level of blood volume. At the time dialysis-induced hypotension occurred or before, there was no sharp decrease in blood volume nor any change in the plasma refilling rate. This suggested that this hypotension is caused by a sudden breakdown of the blood pressure support mechanism compensating for decreased blood volume.

Blood Volume↗
PubMed1988

Effect of carbon dioxide on heat production of frog skeletal muscles.

1. Maintenance heat produced in tetani of frogs' sartorius muscles (Rana japonica) was measured under various values of intracellular pH (pHi) brought about by increasing the CO2 concentration in Ringer solution. The pHi values were measured using 31P nuclear magnetic resonance from the chemical shifts of the inorganic phosphate resonance. The pHi was 7.10 +/- 0.009 (mean +/- S.E. of the mean, n = 10) in the gas mixture of 5% CO2/95% O2 at 4 degrees C and it was reduced to 6.44 +/- 0.001 (n = 23) in 45% CO2. 2. As CO2 was increased, the maximum force was decreased and relaxation was prolonged. This is in accordance with the results of Edman & Mattiazzi (1981) and Curtin (1986). 3. An increase in CO2 induced a reduction of the maintenance heat production, which can be divided into stable and labile heats (Aubert, 1956). The stable heat, which is produced with a steady rate during contraction, was decreased as CO2 was increased. The labile heat, which is produced with an exponentially declining rate, was not significantly altered by increasing CO2 within the range studied. 4. The effect of previous contractile activity on the labile heat production, i.e. the time course of repriming of the labile heat, could be described by an equation with two exponential terms in 5% CO2 in accordance with the result of Peckham & Woledge (1986). The time course of repriming of the labile heat was not affected by increasing CO2 to 20%.

Animals↗
PubMed1988

Effect of protein intake on mineral (calcium, magnesium, and phosphorus) balance in Japanese males.

A 26-day balance study was conducted to examine the effect of a high protein diet on calcium, magnesium, and phosphorus utilization in six healthy males (age 20-22 years, body weight 54.0-64.4 kg, body height 165-173 cm). In addition, the effect of physical exercise on calcium, magnesium, and phosphorus balance was also examined. After a 2-day stabilization period, two levels of protein--control (1.0 g/kg of body weight) and high (2.0 g/kg of body weight) protein--diets were given for three 4-day periods at each protein level. During the last 4-day period of each protein level, subjects exercised on a bicycle ergometer for two 1-h periods daily at a load of 1.5 kp., 50 cyc./min. The high protein diet increased urinary calcium and caused a significant negative calcium balance. Magnesium balance tended to be negative in the control diet. There were no significant changes in urinary calcium, magnesium, and phosphorus and also in the calcium, magnesium, and phosphorus balance during physical exercise.

Adult↗
PubMed1988

Time-resolved 31P nuclear magnetic resonance studies on isometric contraction of frog skeletal muscle.

The time course of changes of inorganic phosphate (Pi) and phosphocreatine (PCr) was studied during and after brief isometric tetanic contractions using phosphorus nuclear magnetic resonance on isolated semitendinosus muscles of the bullfrog at 4 degrees C. We followed essentially the method of Dawson, Gadian and Wilkie and the signal-to-noise ratio was improved by using many muscles. Immediately following the relaxation of contraction, the fall of PCr was not sufficient to account for the Pi released. The level of PCr remained unaltered, or decreased further, in the early post-contractile period. The amount of Pi that appeared without PCr splitting was similar to the amount of myosin sites (0.3 mmol kg-1 muscle) irrespective of the duration of contraction. The post-contractile utilization of PCr was strongly temperature dependent. It was prolonged at 1 degree C, whereas it almost disappeared at 10 degrees C. When the filament overlap was much reduced by stretching the muscles the phenomenon became undetectable. All these results have indicated that the post-contractile utilization of PCr is closely associated with the actin-myosin ATPase cycle.

Animals↗
PubMed1988

[Clinical effects of terodiline hydrochloride for urinary frequency and sense of residual urine].

The clinical effects of terodiline hydrochloride were evaluated in forty-four patients with urinary frequency and/or sense of residual urine. After a four-week treatment with 24 mg terodiline hydrochloride once daily, subjective symptoms were improved and micturition frequency was decreased significantly. Slight dysuria was reported as a side effect only in one patient. Terodiline hydrochloride is considered to be superiorly effective and safe for the treatment of urinary frequency and sense of residual urine.

Adult↗
PubMed1987

Intrahepatic portal-systemic shunt: its etiology and diagnosis.

Four cases of enormous shunt between portal and hepatic veins (portal-hepatic venous shunt) are reported with special reference to sonographic and portographic findings. Ultrasonography, an examination for screening, delineated a snail-like anechoic area in the liver, its connection with the portal and hepatic veins, and marked dilatation of the veins connecting with the shunt. Transarterial or percutaneous transhepatic portography, a method for definitive diagnosis, demonstrated large pooling of the contrast medium flowing from the dilated portal branch and subsequent visualization of the hepatic vein. The etiology and prognosis are unknown at present. The most likely pathogenesis for this shunt seemed to be a congenital anomaly, namely, persistence of the omphalomesenteric venous system. With recent advances in and the more frequent use of real-time ultrasonography, detection of this kind of vascular abnormality will doubtless increase.

Female↗
PubMed1987

Complete evaluation of the cardiovascular lesions in 24 patients with Takayasu's aortitis using four-image, intravenous digital subtraction angiography.

We studied the entire distribution of cardiovascular lesions with the use of intravenous digital subtraction angiography (DSA) in 24 patients having Takayasu's aortitis. The aorta, its branches, pulmonary vessels, and left ventricle were assessed by neck (anteroposterior), abdominal (anteroposterior), and chest (right and left anterior oblique) images. DSA showed multiple arterial lesions (n = 24) including proximal renal artery stenoses (n = 4), pulmonary arterial stenoses (n = 4), inferior-superior mesenteric arterial anastomoses (n = 3), brachiocephalic arterial aneurysms (n = 2), aortic root aneurysm (n = 1), diffuse left ventricular hypokinesis (n = 1), subclavian steal phenomenon (n = 1), and right aortic arch (n = 1). The incidence of total occlusion was highest in the right subclavian artery (n = 12). Average percent luminal stenosis (mean +/- S.D.) over the aorta and its branches tended to be smaller in patients with prior corticosteroid therapy (17.3 +/- 14.6%) than in those without (22.0 +/- 9.8%), but the difference was not significant. DSA (four-series) was useful in assessing the whole disease spectrum and often revealed subclinical lesions in this disease.

Adolescent↗
PubMed1987

[Studies on the usefulness of a long-term, high-dose treatment of methylcobalamin in patients with oligozoospermia].

Methylcobalamin (CH3-B12) was administrated in a dose of 6 mg per day (group A, 16 cases) or 12 mg per day (group B, 23 cases) for 16 weeks to patients with oligozoospermia. There was no difference between group A and group B regarding vitamin B12 concentrations in the serum or seminal fluid. CH3-B12 appeared to be transported to seminal fluid very efficiently. However, results from group A and group B did not differ with respect to this parameter. The efficacy rate for group A was 37.5% and that for group B was 39.1%. From these results, it was concluded that a long-term, high dose treatment of CH3-B12 was useful for the treatment of patients with oligozoospermia. Since the efficacy rates were not different between the two groups, 6 mg per day would be the recommended dose. Clinical adverse reactions were observed in one patient in each group. Drug-related laboratory adverse reactions were observed in only one patient in group B.

Adult↗