[Large extracerebral cavernous angioma in the middle cranial fossa. Case report].
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Biomedical subjects
Publications and source records attributed to T Koba.
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A newly developed reagent strip method for determination of urinary specific gravity is described. This reagent strip (Chemical S.G., Ames Co.) contains polyelectrolyte which is sensitive to the cation in solution. The urinary specific gravity is mainly decided by cation (Na+ and K+) concentrations in urine. As a result, the reagent strip gave measurements that corresponded to those measured by refractometry and gravimetry of NaC1 solution. Urea and glucose gave increased values by the refractometer, whereas the reagent strip did not cause changes. The values of urinary specific gravity obtained from reagent strip showed not only good correlations (r = 0.79-0.93) with the refractometry and gravimetry but also urinary osmolarity. This reagent strip method proved to be a most convenient tool for routine urinalysis because of the good reproducibility and accuracy considering its easy handling.
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The authors review 38 cases of hypertensive intracerebral hemorrhage operated on within 7 hours after the apoplectic attack. Microsurgical technique was used for hemostasis and evacuation of the hematoma. At the 6-month follow-up study, 34 patients could walk unaided or with a cane, one was confined in bed, and three had died.
In 1967, Fisher named the "one and a half syndrome" for a particular ocular movement which is observed in the lesion of pontine tegmentum, when horizontal movement of one eye is totally disabled and the abducence of another eye is only preserved associating mono-ocular nystagmus in the same eye. Vertical movement and convergence are preserved. We experienced this syndrome in four cases of small localized hematoma of the pontine tegmentum which were all removed under operative microscope. All patients are alive more than 10 months under consciousness and with improved neurological sign. Three of them were probably due to hypertensive hemorrhage and the rest was due to arterio-venous malformation of the pontine tegmentum. Three of them showed this syndrome before operation and observed even after operation. One patient was operated on one and a half hours after the apoplectic attack under semicomatous condition and he improved with this syndrome postoperatively. In most previous reports, this syndrome was noted in severe cases of pontine hematoma or basilar artery thrombosis and they expired soon thereafter. All our cases survived in satisfactory condition and ocular movement could be followed up for a long time. The mechanism of this syndrome was also discussed.
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As a causative factor in spontaneous subarachnoid hemorrhage, vascular anomalies, especially aneurysm or arteriovenous malformation, have been generally recognized. On the other hand, subarachnoid hemorrhage from brain tumor and cryptic vascular malformation are rare. We experienced two cases showing subarachnoid hemorrhage from angioblastic meningioma and vascular hamartoma as an initial symptom. Case 1: A 48-year-old woman, who complained of severe headache and vomiting on Feb. 10th, 1972, gradually became lethargic. Lumbar puncture revealed moderately hemorrhagic C.S.F.. On the fifth day after the onset, she was admitted to our hospital. On admission she showed disorientation and disturbance of resent memory. Aphasia and agnosia were slightly observed. On ophthalmologic examination right homonymous lower quadrant hemianopsia was observed. The carotid angiogram showed slight square shift of the anterior cerebral artery to the right side, elevation of the middle serebral artery and a homogeneous tumor stain in the occipital region in capillary phase. A walnut sized tumor invading the middle portion of the left lateral sinus and showing firm adhesion to the tentrium was found. There was an intracerebral hematoma behined the tumor. The tumor, the tentrium and the lateral sinus were extirpated en bloc and the intracerebral hematoma was aspirated. Histologically, the tumor was angioblastic meningioma. Case 2: A 7-year-old boy, who complained of severe abrupt headache, nuchal pain and vomiting on Sept. 17th, 1972, became gradually lethargic. Lumbar puncture revealed hemorrhagic C.S.F., On the tenth day after the onset, he was admitted to our hospital. He showed confusion and agitation. The carotid angiogram showed an unrolling of the pericallosal artery, but no findings of space taking lesions. An air study indicated a globular filling defect protruding into the anterior horn of the right lateral ventricle. The tumor located in the laterobasal wall of the anterior horn was removed picemiel by transventricular approach. Histologically, the tumor was vascular hamartoma. Furthermore, we discussed various brain tumors showing subarachnoid hemorrhage as an initial symptom, its frequency and bleeding mechanism on the literature.
The authors studied the Pantopaque radiograms of a hematoma cavity in 46 patients following early surgical treatment for the lateral type of hypertensive intracerebral hematoma. All patients were operated on within 7 hours after the apoplectic attack and most of them had a localized hematoma. It was concluded that they could be classified in three subtypes from the location of hematoma in the antero-posterior direction. Each subtype had particular clinical symptoms and prognosis.