PubMed Health⌕ Search

Biomedical subjects

T Kuramata

Publications and source records attributed to T Kuramata.

At least 19 recordsLinked to original sources
PubMed1992

[A study on the disc sensitivity test for cefodizime].

Susceptibilities of 289 strains of 34 bacterial species to cefodizime (CDZM) were determined using the 2-fold agar dilution method in parallel with the measurement of inhibition zone diameters in the single-disc method under the experimental conditions established by Kanazawa. The experiments demonstrated a significant correlation between MIC by the dilution method and diameter of inhibition zone in each of the conventional, overnight assay (about 16 hours incubation), thus the applicability of the single-disc assay for CDZM was established. Analysis of the data obtained using discs containing 30 micrograms of CDZM/disc revealed that the primary regression equation was in the form: D (Diameter, mm) = 32.3-13.5 log MIC (micrograms/ml) in the conventional assay for staphylococci, Enterococcus group and glucose-non-fermentative Gram-negative rods. For other bacteria, the primary regression equation was in the form: D (diameter, mm) = 24.1-8.4 log MIC (micrograms/ml) in the conventional assay. The range of variations in MICs estimated from diameters of inhibition zones in the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution test to estimate experimental errors which may be involved in the determination of MICs of CDZM using the single-disc assay.

Bacteria↗
PubMed1991

Muscle soreness and serum enzyme activity following consecutive drop jumps.

The purpose of this study was to evaluate changes in muscle soreness and serum enzyme activity following consecutive drop jumps. Seven male subjects (mean age 30.6 years) performed drop jumps from a 80-cm box height every 7 s until exhaustion (mean = 114 drop jumps). A questionnaire was used to assess muscle soreness (0 = no pain, 7 = unbearable painful) both pre- and post-exercise (0, 12, 24, 36 and 48 h, and 3, 4 and 5 days after the exercise). Blood samples were also taken from three subjects at each of these times. For the other four subjects, blood samples were taken pre-exercise and 0, 12 and 36 h and 5 days post-exercise only. Although there was large inter-subject variability in the development of muscle soreness, all the subjects reported muscle soreness in their lower extremity muscles, especially in the quadriceps femoris. Muscle soreness developed significantly (P less than 0.01) over time, its peak (mean +/- S.E. = 3.7 +/- 0.7) occurring 12-48 h post-exercise. Serum enzyme activity changed significantly over time (P less than 0.05), but the changes were small. Not one subject showed a large increase in creatine kinase, and the average increase was less than 1.3 times as much as the pre-exercise level throughout the period of study. These results suggest that the muscle damage that occurs after drop jumping is not associated with a large release of muscle enzymes into the blood, and muscle soreness is not necessarily related to enzyme elevation following drop jumps.

Adult↗
PubMed1991

[A study on the disc sensitivity test for cefpirome].

Susceptibilities of 232 strains of 40 bacterial groups to cefpirome (CPR) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zones by the single-disc method under the experimental conditions established by Kanazawa. The experiments demonstrated a significant correlation between MIC by the dilution method and diameter of inhibition zone in each of the conventional assay of over-night (about 16 hours) incubation, the delayed assay (about 24 hours incubation), and the rapid assay (about 3-4 or 5-6 hours incubation), thus confirming the applicability of the single-disc assay for CPR. Analysis of the data obtained by using CPR disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 26.7-9.2 log MIC (micrograms/ml) in the conventional assay, D = 33.8-12.7 log MIC (micrograms/ml) in the delayed assay, D = 21.2-6.7 log MIC (micrograms/ml) in 5-6 hours rapid assay, and D = 14.8-4.1 log MIC (micrograms/ml) in 3-4 hours rapid assay. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution test, as a reference for the experimental errors which may be involved in the estimation of MIC of CPR by the single-disc assay.

Cephalosporins↗
PubMed1988

[A study on the disc sensitivity test for clavulanic acid/amoxicillin combination].

Susceptibilities of 179 strains of 30 bacterial species or subspecies to clavulanic acid/amoxicillin (CVA/AMPC) combination were determined by the 2-fold agar dilution method as well as by diameters of inhibition zones in the single-disc method, under the experimental conditions established by Kanazawa. The experiments demonstrated significant correlation between MICs by the dilution method and diameters of inhibition zones in each of conventional assays of the over-night (about 16 hours) incubation, the delayed assay (about 24 hours incubation), and the rapid assay (after 3-4 or 5-6 hours incubation), thus confirming applicability of the single-disc assay for activities of CVA/AMPC combination. From an analysis of the data obtained using CVA/AMPC (1:2) combination of disc containing 45 micrograms, the primary regression equations were obtained as follows: D (diameter, mm) = 27.4-10.1 log MIC (micrograms/ml) in the conventional assay; D = 33.7-13.4 log MIC (micrograms/ml) in the delayed assay; D = 20.7-6.6 log MIC (micrograms/ml) in the 5-6 hours rapid assay, and D = 14.5-3.6 log MIC (micrograms/ml) in the 3-4 hours rapid assay. The range of variations in MICs of CVA/AMPC combination estimated from diameters of inhibition zones by the disc test was then calculated in comparison with that in MICs determined by the 2-fold agar dilution method to estimate experimental errors involved in assaying MICs of CVA/AMPC combination by the single-disc assay.

Amoxicillin↗
PubMed1986

[A study on the disc sensitivity for ceftizoxime].

Susceptibilities of 175 strains of 27 bacterial species to ceftizoxime (CZX) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zones by the single-disc method under the experimental conditions established by Kanazawa. The experiments demonstrated a significant correlation between MIC by the dilution method and diameter of inhibition zone in each of the conventional assay of over-night (about 16 hours) incubation, the delayed assay (about 24 hours incubation), and the rapid assay (about 3 approximately 4 or 5 approximately 6 hours incubation), thus confirming the applicability of the single-disc assay for CZX. Analysis of the data obtained by using CZX disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 27.3-9.7 log MIC (micrograms/ml) in conventional assay, D = 32.5-12.3 log MIC (micrograms/ml) in delayed assay, D = 22.8-7.5 log MIC (micrograms/ml) in 5 approximately 6 hours rapid assay, and D = 17.9-5.1 log MIC (micrograms/ml) in 3 approximately 4 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution test, as a reference for the experimental errors which may be involved in the estimation of MIC of CZX by the single-disc assay.

Bacteria↗
PubMed1986

[A study of the disc sensitivity test for cephapirin].

Susceptibility of 203 strains of 34 bacterial species or subspecies to cephapirin (CEPR) was determined by the 2-fold agar dilution method in parallel with the determination of inhibition zone diameter in the single-disc method. These experiments demonstrated a significant correlation between the MIC by the dilution method and the diameter of inhibition zone determined by the conventional assay using an over-night (about 16 hours) incubation, the delayed assay (about 24 hours incubation), or the rapid assay (after 3-4 or 5-6 hours incubation), hence applicability of the single-disc assay for CEPR was confirmed. An analysis of the data obtained using CEPR discs (each containing 30 micrograms) revealed that primary regression equations were as follows: D (diameter, mm) = 25.8-9.7 log MIC (microgram/ml) in the conventional assay; D = 31.2-12.3 log MIC in the delayed assay; D = 21.7-7.1 log MIC in the 5-6-hour rapid assay and D = 17.9-5.0 log MIC in the 3-4-hour rapid assay, and especially for beta-lactamase producing Staphylococci, they were: D = 24.9-9.2 log MIC in the conventional assay, D = 20.4-7.4 log MIC in the 5-6-hour rapid assay and D = 17.5-5.8 log MIC in the 3-4-hour rapid assay.(ABSTRACT TRUNCATED AT 250 WORDS)

Agar↗
PubMed1984

[A study on the disc sensitivity test for cefmenoxime].

Susceptibilities of 77 strains of 24 bacterial species to cefmenoxime (CMX) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zones by the single-disc method, under the experimental condition established by Kanazawa . The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (about 3 approximately 4 or 5 approximately 6 hours incubation), thus confirming applicability of the single-disc assay for CMX. Analysis of the data obtained by using CMX disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 25.5-9.3 log MIC (micrograms/ml) in conventional assay, D = 30.8-12.0 log MIC (micrograms/ml) in delayed assay, D = 20.9-6.9 log MIC (micrograms/ml) in 5 approximately 6 hours rapid assay, and D = 16.8-4.8 log MIC (micrograms/ml) in 3 approximately 4 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of CMX by the single-disc assay.

Agar↗
PubMed1984

[A study on the disc sensitivity test for amoxicillin].

Susceptibilities of 101 strains of 25 bacterial species or subspecies to amoxicillin (AMPC) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental conditions established by Kanazawa. The experiments demonstrated significant correlation between the MIC by the dilution method and the diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 3 approximately 4 or 5 approximately 6 hours incubation), thus confirming applicability of the single-disc assay for AMPC. Analysis of the data obtained by using AMPC disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 27.1-9.9 log MIC (micrograms/ml) in conventional assay, D = 32.2-12.8 log MIC (micrograms/ml) in delayed assay, D = 19.8-6.2 log MIC (micrograms/ml) in 3 approximately 4 hours rapid assay, and D = 24.0-7.8 log MIC (micrograms/ml) in 5 approximately 6 hours rapid assay, and particularly for beta-lactamase producing Staphylococci, D = 23.7-8.1 log MIC (micrograms/ml) in conventional assay, D = 16.7-9.0 log MIC (micrograms/ml) in 3 approximately 4 hours rapid assay, and D = 20.7-9.2 log MIC (micrograms/ml) in 5 approximately 6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of AMPC by the single-disc assay.

Amoxicillin↗
PubMed1983

[A study on the disc sensitivity test for cefatrizine].

Susceptibilities of 227 strains of 34 bacterial species to cefatrizine (CFT) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zones by the single-disc method, under the experimental condition established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 3-4 or 5-6 hours incubation), thus confirming applicability of the single-disc assay for CFT. Analysis of the data obtained by using CFT disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 25.6--9.6 log MIC (micrograms/ml) in conventional assay, D = 33.2--13.2 log MIC (micrograms/ml) in delayed assay, D = 15.8--4.7 log MIC (micrograms/ml) in 3-4 hours rapid assay and D = 20.2--7.0 log MIC (micrograms/ml) in 5-6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of CFT by the single-disc assay.

Bacteria↗
PubMed1983

[A study of the disc sensitivity test for cefaclor].

Susceptibilities of 169 strains of 30 bacterial species to cefaclor (CCL) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zones by the single-disc method, under the experimental condition established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 3-4 or 5-6 hours incubation), thus confirming applicability of the single-disc assay for CCL. Analysis of the data obtained by using CCL disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 28.2--10.2 log MIC (micrograms/ml) in conventional assay, D = 33.8--13.0 log MIC (micrograms/ml) in delayed assay, D = 17.9--5.1 log MIC (micrograms/ml) in 3-4 hours rapid assay and D = 22.6--7.4 log MIC (micrograms/ml) in 5-6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of CCL by the single-disc assay.

Bacteria↗
PubMed1983

[Evaluation of the disc sensitivity test for cefmetazole].

Susceptibilities of 198 strains of 31 bacterial species to cefmetazole (CMZ) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental condition established by Kanzazwa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the overnight (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (about 3-4 or 5-6 hours incubation), thus confirming applicability of the single-disc assay for CMZ. Analysis of the data obtained by using CMZ disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 27.9-11.2 log MIC (micrograms/ml) in conventional assay, D = 34.5-13.8 log MIC (microgram/ml) in delayed assay D = 18.1-6.0 log MIC (microgram/ml) in 3-4 hours rapid assay and D = 22.9-8.5 log MIC (microgram/ml) in 5-6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of CMZ by the single-disc assay.

Bacteria↗
PubMed1983

[Disc sensitivity test of cefuroxime].

Susceptibility of 124 strains of 28 bacterial species or subspecies to cefuroxime were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 3 approximately 4 or 5 approximately 6 hours incubation), thus confirming applicability of the single-disc assay for cefuroxime. Analysis of the data obtained by using cefuroxime disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 28.2-10.1 log MIC (micrograms/ml) in conventional assay, D = 33.1-13.2 log MIC (micrograms/ml) in delayed assay, D = 23.9-8.2 log MIC (micrograms/ml) in 5 approximately 6 hours rapid assay, and D = 20.0-6.5 log MIC (micrograms/ml) in 3 approximately 4 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold dilution assay, as reference for the experimental errors which may be involved in the estimation of MIC of cefuroxime by the single-disc assay.

Animals↗
PubMed1983

[Disc sensitivity test for micronomicin].

Susceptibilities of 228 strains of 32 bacterial species to micronomicin (MCR) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental conditions established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 5--6 or 3--4 hours incubation), thus confirming applicability of the single-disc assay for MCR. Analysis of the data obtained by using MCR disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 25.7-9.5 log MIC (micrograms/ml) in conventional assay, D = 30.3-11.6 log MIC (micrograms/ml) in delayed assay, D = 21.0-7.0 log MIC (micrograms/ml) in 5--6 hours rapid assay, D = 16.8-4.8 log MIC (micrograms/ml) in 3--4 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of MCR by the single-disc assay.

Aminoglycosides↗
PubMed1983

[A study on the disc sensitivity test for cefsulodin].

Susceptibilities of 101 strains of 34 bacterial species to cefsulodin (CFS) were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental condition established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (about 3--4 or 5--6 hours incubation), thus confirming applicability of the single-disc assay for CFS. Analysis of the data obtained by using CFS disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 30.0 - 12.1 log MIC (micrograms/ml) in conventional assay, D = 36.3 - 15.6 log MIC (micrograms/ml) in delayed assay, D = 25.2 - 9.0 log MIC (micrograms/ml) in 5--6 hours rapid assay, and D = 20.4 - 6.4 log MIC (micrograms/ml) in 3--4 hours rapid assay, respectively. The range of variations in MICs estimated from the diameters of inhibition zone by the disc test was then calculated in comparison with that in MICs determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MICs of CFS by the single-disc assay.

Bacteria↗
PubMed1982

[A study of the disc sensitivity test for cefotiam].

Susceptibilities to cefotiam of 103 strains of 27 bacterial species were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental condition established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (about 3--4 or 5--6 hours incubation), thus confirming applicability of the single disc assay for cefotiam. Analysis of the data obtained by using cefotiam disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 25.6--10.1 log MIC (micrograms/ml) in conventional assay, D = 32.8--13.2 log MIC (micrograms/ml) in delayed assay, D = 17.2--5.8 log MIC (micrograms/ml) in 3--4 hours rapid assay and D = 21.0--7.8 log MIC (micrograms/ml) in 5--6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of cefotiam by the single-disc assay.

Anti-Bacterial Agents↗
PubMed1982

[A study of the disc sensitivity test for cefotaxime].

Susceptibility of 101 strains of 29 bacterial species to cefotaxime were determined by the 2-fold agar dilution method in parallel with the diameter of inhibition zone by the single-disc method, under the experimental condition established by Kanazawa. The experiments demonstrated significant correlation between MIC by the dilution method and diameter of inhibition zone in each of conventional assay of the over-night (about 16 hours) incubation, delayed assay (about 24 hours incubation), and rapid assay (after 3 approximately 4 or 5 approximately 6 hours incubation), thus confirming applicability of the single-disc assay for cefotaxime. Analysis of the data obtained by using cefotaxime disc containing 30 micrograms revealed the primary regression equation to be: D (diameter, mm) = 26.5-9.4 log MIC (microgram/ml) in conventional assay, D = 33.1-11.7 log MIC (microgram/ml) in delayed assay, D = 16.8 log MIC (micrograms/ml) in 3-4 hours rapid assay and D = 21.4-6.6 log MIC (micrograms/ml) in 5-6 hours rapid assay, respectively. The range of variations in MICs estimated from the diameter of inhibition zone by the disc test was then calculated in comparison with that in MIC determined by the 2-fold agar dilution assays, as reference for the experimental errors which may be involved in the estimation of MIC of cefotaxime by the single-disc assay.

Bacteria↗