PubMed Health⌕ Search

Biomedical subjects

T Kwiatkowski

Publications and source records attributed to T Kwiatkowski.

32 records · Page 2Linked to original sources
PubMed1993

Safety of lumbar puncture in patients with hemophilia.

STUDY OBJECTIVE: To determine the safety of lumbar puncture in patients with hemophilia who are pretreated with clotting factor. DESIGN: Retrospective analysis of medical records between 1980 and 1990. SETTING: Three hospitals, each serving as a regional hemophilia center. PARTICIPANTS: Thirty-three patients with hemophilia A or B who received one or more lumbar puncture. INTERVENTION: All patients received replacement of deficient factor before the lumbar puncture. Serious post-lumbar puncture complications were defined as motor or sensory deficits, incontinence, or documented intraspinal hemorrhage. RESULTS: Thirty-three patients with hemophilia A or B received a total of 52 lumbar punctures during the study period. Thirty of 33 patients (91%) had severe baseline factor deficiency, two (6%) had moderate deficiency, and one (3%) had mild deficiency. There were no serious complications reported as a result of the lumbar puncture. The 95% confidence interval for the risk of a serious complication was 0% to 5.8%. CONCLUSION: With adequate factor replacement, a lumbar puncture can be done safely in patients with hemophilia.

Adolescent↗
PubMed1993

Studies on liver sufficiency of cows fed on food with unbalanced mineral composition.

In 90 cows of black white and red white race, aged 3-9 years and of 450 kg mean body weight fed on food with low level of Ca, P, and Na, several parameters of protein, carbohydrates and lipid liver metabolism before and after supply of special mineral mixtures were evaluated. After the supply the increased concentration of total protein, urea and cholesterol esters and decrease of AspAT, AlAT, and AP activities were recorded in the blood. Cholesterol esters: total cholesterol ratio improved and a slight increase of milk yield and content of fat in milk was observed. Food mineral mixtures favourably influenced the stabilization of liver metabolism.

Animal Feed↗
PubMed1993

Influence of animal and plant fat addition in pasture and winter feeding of high yielding cows at first stage of lactation on productivity and physiological profiles.

200 g of fat in the form of greased wheat bran, was given cows during pasture feeding. For winter feeding on hay and silages the amount was 400 g of greased wheat bran or 400 g of oil in ground rapeseed per day and per animal. Influence of the fat addition on the yield and milk composition was observed in the case of pasture experiment. No such influence was observed in the winter feeding. Addition of fat advantageously influenced the chemical constituents in the cow blood in both experiments.

Animal Feed↗
PubMed1991

Induction of antibody response to Chlamydia trachomatis in the genital tract by oral immunization.

Groups of BALB/c mice were orally immunized with Chlamydia trachomatis serovar L2/434/Bu in order to characterize the nature and kinetics of the chlamydial antibody response in the cervix and other mucosal sites. These animals were subsequently challenged intravaginally to determine whether oral immunization offers protection against chlamydial antigen shedding in the genital tract. Following oral immunization, immunoglobulin A antibody activity was detected in the genital tract as well as other mucosal sites. Subsequent intravaginal challenges exhibited booster effects on preexisting antibody activity in the genital tract. Significant protection against challenge infection in the genital tract was observed by oral immunization. This was indicated by the absence of any chlamydial antigen shedding in cervical secretions. On the other hand, passively administered chlamydial-specific serum immunoglobulin G antibody did not significantly influence the course of cervical shedding of the organism and did not confer any protection against a subsequent intravaginal challenge. It is concluded that prior oral immunization can induce a secretory antibody response in the genital tract and provide protection against subsequent infection.

Administration, Oral↗
PubMed1989

[Evaluation of the indicators of protein, carbohydrate and mineral metabolism in the blood of cows fed supplementary high-energy food].

Cows of the white-black breed from the Sudeten piedmont were divided into two groups: control and experimental. Both groups were fed the same basic fodder, e.g. pasture, green forage of clover and maize, and hay; afterwards they were fed grass silage, hay and beets. Maize forage, containing little fibrin, lot of starch and soluble carbohydrates, was substituted by grass silage with little starch and soluble carbohydrates, but rich in cellulose and hemicelluloses. So, energetic value of the food was different. The chosen chemical indices were estimated during the change of fodder from pasture to winter silage and hay. Cows from the control group were fed additionally, one month before calving, 1 kg of the protein food (bruised barley) without urea, whereas cows from the experimental group were fed additionally with bruised barley, in the amount of 1.5-3 kg, when giving less than 4000 l of milk, and 2.5-4 kg, when giving over 4000 l of milk. The amount of food increased by 0.5 kg every week beginning with smallest dose. This additional feeding had positive influence on the milk production, especially in the 2nd and 3rd month after calving (2.3 kg during 4 months after calving), and improved the effectivity of fertilization after the first insemination. The chemical composition of the milk has not been changed significantly; the total protein and its fraction, levels of urea, Ca, Fe and Mg in the blood plasma have not been changed. Only the level of ketones in blood decreased a little. During the transition period, green forage feeding caused the increase of the glucose level in blood to 60 mg% (50 mg% in winter). Additional energetic feeding of cows before calving improved productivity indices and did not change the internal body balance (homeostasis).

Animal Nutritional Physiological Phenomena↗
PubMed1986

[The protein-synthesizing function of the liver in dairy cows fed feed with the addition of various urea preparations and different doses of urea].

It was compared the effect of different preparations containing urea on the productivity and on the blood content of the biochemical compounds informing about protein synthesis activity in the liver of milk cows. The following preparations were added alternatively to the food to 28 cows in a quantity equal with 150 Gm in the first year and with 200 Gm of pure urea in the second year of experimentation for cow and for day: 1. Melwit--a liquid food supplementation containing 5 per cent of urea, 2. Wałczan--"Sterea"-like preparation with 30 p.c. of urea, 3. Ekstruder--"Golden-Pro"-like preparation with 20 p.c. of urea and 4. BW preparation (concentration) for dairy cows containing only plant protein, without urea. In the plasma of all animals was observed the increase of urea, total protein and albumin content and of the activity of following enzymes: AP, AAP, Arg, LAP, AspAT and of A1AT. The content of total and of direct bilirubin in plasma did not change significantly. All examined compounds did not exceed the physiological range. The greatest changes were observed after feeding with Extruder. The physiological decline of milk production after calving was smallest in group fed with Wałczan (2.4 litres) and greatest in Ekstruder group (4.4 litres) when in Melwit 3.4 and in BW 3.5 litres was noticed. The authors stated that the most suitable form of preparation containing urea was Wałczan in the first place and Melwit in the second.

Animal Feed↗
PubMed1986

[Selected factors of metabolism in ruminants fed with increasing doses of urea in the food. I. Liver function in cows in the light of the activity of selected enzymes and the levels of indicators of protein metabolism].

The authors studied the influence of urea added to diet in an amount of 150 grams daily per 1 cow on the function of the liver by means of: determination of the activity of the following enzymes: arginase, ornithin-carbamyl-transferase, leucyloaminopeptidase, gamma-glutamyl-transferase, phosphatase alkaline, determination of the level of total protein, albumins and globulins, urea, sodium and potassium in the serum of dairy cows. No significant changes were found in the activity and in the content of the above mentioned blood constituents. The dose of 150 grams of urea added to diet did not show any disturbances in protein metabolism in the liver and in the health of the cows.

Animal Feed↗
PubMed1983

[Testosterone levels of the plasma of bulls in relation to growth, breed, semen quality and sexual activity].

Using Anderson's method for estimation of testosterone level by competitive protein binding, the authors determined plasma testosterone level in young bulls of three breeds: black and white, and red and white lowland. It was found that in bulls of black and white and red and white lowland breed the testosterone level showed great fluctuations without growing tendency. In charolais bulls, in pubescence, testosterone level was low and did not exceed 1 ng/1 ml, but it systematically increased beginning from the 14th month of life. No correlation of testosterone level with protein and energy intake or with sexual activity was observed in adult bulls (breeders) of black and white lowland breed during 12 months of examination.

Animals↗