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Biomedical subjects

T L Slovis

Publications and source records attributed to T L Slovis.

At least 73 records · Page 4Linked to original sources
PubMed1989

Complicated appendiceal inflammatory disease in children: pylephlebitis and liver abscess.

Five children with complicated appendiceal inflammatory disease are reported. They presented with nonspecific signs and symptoms, but three had liver abscess and two had inflammation of the portal vein. The inflamed portal vein may act as a conduit to the liver for bacteria, or it may become thrombosed and cause portal hypertension and hypersplenism. In one child, symptomatic portal hypertension developed 10 years after the initial disease. In children, an ultrasonic finding of a focal liver mass of low-to-mixed echogenicity or the presence of low-attenuation areas on computed tomographic scans should suggest the possibility of a hepatic abscess, and the radiologist has a major role in suggesting complicated inflammatory disease of the appendix as the cause. Similarly, when portal vein thrombosis or portal hypertension are found, the radiologist should consider complicated inflammatory disease of the appendix as the cause.

Adolescent↗
PubMed1988

Update on pediatric chest imaging.

Even in the high-technology medical imaging arena, the decision of how to first image pediatric chest disease is quite simple: by plain chest radiograph, including frontal and lateral views. The diagnosis can often be made or suggested on the basis of these films or with other basic imaging procedures, such as fluoroscopy or esophagram. From this point onward the decision how to proceed with further imaging such as ultrasound, computed tomography, nuclear medicine imaging, or magnetic resonance imaging, will depend on the probability of gaining further helpful information. Beginning with a concise differential diagnosis allows one to proceed in a logical manner through the diagnostic work-up in a time-effective and cost-effective manner. One must keep in mind that in some cases the diagnosis cannot be made radiologically and must be left to the pathologist. In these cases the work-up should end when no further progress is possible toward making the diagnosis. In the pediatric age group, one should always strive to limit the amount of unnecessary radiation exposure.

Child↗
PubMed1988

Ultrasonographic findings (CNS, thorax, abdomen) in infants undergoing extracorporeal oxygenation therapy.

Extracorporeal membrane oxygenation (ECMO) has been performed on 45 neonates at the Children's Hospital of Michigan in a 39-month period. Ultrasound evaluation of these patients prior to and during ECMO therapy has demonstrated abnormalities in the central nervous system including intracranial hemorrhage (21), extra-axial fluid collections (5), and ventricular enlargement (2). Ultrasonic evaluation of the thoracic cavity in 12 infants revealed pleural fluid in 8. There were seven children with varying types of peritoneal fluid. Two children had visceral abnormalities - 1 with liver hemorrhage and 1 with hydronephrosis found prior to ECMO. Most of these findings could not have been diagnosed without ultrasound and may lead directly to alterations in clinical management. Ultrasound is an extension of physical examination which is important in hour-by-hour clinical care of patients on ECMO.

Ascitic Fluid↗
PubMed1988

Ultrasound diagnosis of adrenal hemorrhage in meningococcemia.

Two cases of adrenal hemorrhage in meningococcemia detected by ultrasound are reported. Antemortem detection of adrenal pathology may have important prognostic and therapeutic implications. The sonographic appearance may be echo-free, mixed, or echogenic. Abdominal ultrasound examination can be an effective non-invasive tool in diagnosing adrenal hemorrhage.

Adrenal Gland Diseases↗
PubMed1988

The renal lesions of tuberosclerosis (cysts and angiomyolipoma)--screening with sonography and computerized tomography.

The two most common sonographic abnormalities in the kidneys of 23 tuberous sclerosis (TS) patients ranging in age from newborn to 30 years are angiomyolipomas (12/23) (AML) and renal cysts (10/23). These usually both occur in the same patient with only 9 cases (39%) having sonographically normal kidneys. Of the 14 affected patients, 2 had cysts without AML and 4 others had AML without cysts. The sonographic appearance of an AML varied from a large 6 cm solid mass with little increased echogenicity (1/12) to subtle small (4 mm) extremely echogenic regions in the periphery of the kidney (11/12). The sonographic appearance of the cysts were anechoic lesions varying in size from 2 mm to 2 cm with thin uniform posterior walls and posterior enhancement. Renal lesions are found more frequently with increasing age. Sonography is the preferred screening procedure for the renal lesions of T.S.

Adolescent↗
PubMed1988

Optimal use of 99mtechnetium-glucoheptonate scintigraphy in the detection of pyelonephritic scarring in children: a preliminary report.

Renal scintigraphy represents the optimal modality for the detection of renal scars. 99mTechnetium-glucoheptonate is rapidly accumulated by the kidney through glomerular filtration and active transport by renal tubular cells. This permits rapid visualization of the renal parenchyma in the early phase (1 to 3-minute images) and subsequent imaging of the collecting system and ureters. About 10 to 15 per cent of the injected activity remains in the kidney, labeling the cells of the proximal convoluted tubules (late phase or 1 to 2-hour images). The late phase has been used more commonly to assess renal parenchymal damage. Early and late phase glucoheptonate scanning was performed in 42 children as part of the evaluation of recurrent febrile urinary tract infections with or without a history of vesicoureteral reflux. Inter-observer reliability to interpret glucoheptonate scans was good (early, 83 per cent agreement and late, 93 per cent agreement). The ability of glucoheptonate scanning to detect renal scarring in children with febrile urinary tract infections was equivalent with the early or late phase of the study. In 6 patients renal scarring was detected on only the early phase scan and in 7 scarring was detected only in the late phase. Although the detection rates are equivalent the over-all detection of scarring is improved by using both phases. Therefore, the early phase of the glucoheptonate scan may be a valuable adjunct to conventional glucoheptonate scan methodology used for the detection of renal scarring in children with recurrent urinary tract infections.

Adolescent↗
PubMed1988

Follow-up studies of multicystic dysplastic kidneys.

Thirty cases of multicystic dysplastic kidney (MCDK) were diagnosed over 11 years. Nine patients underwent nephrectomy: three for increasing kidney size (classic MCDK) and six because of an inconclusive diagnosis (hydronephrotic MCDK). Of the remaining 21 patients, 19 were followed up for a mean of 33.5 months (range, 2-101 months). Follow-up ultrasound examinations revealed that 16 kidneys did not change in size, one decreased in size after cyst puncture, and two disappeared (one after cyst puncture). This series included one case of non-renin-producing hypertension that was controlled medically, one case of nephroblastomatosis found in the removed dysplastic kidney, and one case of pyelonephritis in the contralateral kidney. When the diagnosis of classic MCDK is made with imaging modalities, the lesion may not have to be removed unless there is growth of the mass during the 1st year of life. Nine percent of these lesions will disappear within the first 3 years of follow-up, and the authors recommend an even longer period of follow-up.

Child↗
PubMed1986

Endotracheal tubes in neonates: sonographic positioning.

Twenty-one real-time sonographic determinations of endotracheal tube tip position were performed in 16 neonates. Findings were compared with those from simultaneously obtained chest radiographs. Relation of the tube tip to the aortic arch provided a reliable method of determination of appropriate position. Optimal tube tip position was seen when the tube tip was 1 cm above the arch.

Humans↗
PubMed1985

Normal values for ventricular size as determined by real time sonographic techniques.

Seventy-three real time sonographic scans were performed through the anterior fontanelle of 67 infants between 28 and 48 weeks post-conception who had no evidence of intracranial disease. Several anatomical measurements were plotted against independent variables such as post-conception age, weight and head circumference at the time of the examination. All of the measurements increased as age, weight and head circumference increased. Ratios formed by dividing transventricular diameters by transcalvarial diameters at the two levels in the coronal plane and by dividing occipital mantle thickness by frontal mantle thickness in the parasagittal planes remained stable as all of the independent variables increased. In 88% of cases the occipital mantle could not be measured since the occipital horns of the lateral ventricles could not be identified. Since dilation of the ventricular system starts in the occipital horns of the lateral ventricles, non-visualization of this area is an important negative finding.

Body Weight↗
PubMed1985

Renal manifestations of Kawasaki's disease.

Renal sonographic evaluation of seven patients with mucocutaneous lymph node syndrome were performed and correlated with clinical and laboratory data either supporting or not supporting renal disease associated with this entity. Four of seven patients demonstrated significant elevations of the BUN, creatinine and/or significant proteinuria. These four patients had renal sonographic findings of increased cortical echogenicity, enlarged kidneys and enhanced corticomedullary differentiation. This complication of mucocutaneous lymph node syndrome has heretofore not been noted.

Child↗
PubMed1985

Simple renal cysts in infants.

Two cases of renal cysts in infants less than one year of age are presented. In both instances percutaneous puncture of the cyst aided in establishing the diagnosis without the need for an operative procedure.

Contrast Media↗
PubMed1985

Choanal atresia: precise CT evaluation.

Computed tomography facilitates the diagnosis of children with choanal atresia. This modality defines the full anatomic abnormality of bony choanal atresia: medial bowing and thickening of the lateral wall of the nasal cavity, enlargement of the vomer, and fusion of these elements. Bony atresia patients can be clearly separated from those with membranous choanal atresia. In membranous atresia, the lateral wall of the nasal cavity is minimally affected and the vomer is normal. This precise anatomic evaluation aids in determining the surgical approach.

Child, Preschool↗
PubMed1985

Renal transplants in children: long-term follow-up using sonography.

Sonographic findings more than 1 year after transplantation for 16 children with renal transplants were reviewed to determine the appearance of the transplant on long-term follow-up and to correlate its sonographic appearance with its function. The appearance of the transplant varied considerably, and there was no association between renal function and renal volume, shape, parenchymal echogenicity, or central sinus echoes. Renal size and donor age were negatively associated. In children, a change in renal size greater than the usual 90%-130% of baseline volume seen in adults is a normal adaptation of the transplanted kidney to the recipient body size. Sonography was not useful for diagnosing chronic rejection or predicting function in the pediatric transplant patient.

Adolescent↗
PubMed1985

Intracranial calcification in the infant and neonate: evaluation by sonography and CT.

This study reports the sonographic and computed tomography (CT) findings in seven infants and neonates with intracranial calcifications and a spectrum of underlying disorders, including toxoplasmosis, cytomegalic inclusion disease, transverse/straight sinus thrombosis, and probable anoxia. Neurotropic infectious disease usually produced clumped or subependymal calcifications accompanied by sometimes bizarre ventricular configurations and prominent periventricular cystic encephalomalacia. Sonography failed to identify prospectively intracranial calcifications in two of the three patients without infection, although calcifications were visible in retrospect. Overall, CT provided optimum visualization of intracranial calcifications.

Brain Diseases↗
PubMed1984

Noninvasive evaluation of the inferior vena cava. The value of sonography.

Children who have abnormalities of the inferior vena cava (IVC) appear with diverse signs and symptoms. Those with congenital IVC malformations have symptoms related to associated cardiac disease. Those with IVC compression or obstruction may have ascites, hepatomegaly, edema of the lower extremities, and/or signs of portal hypertension. Sonography of the IVC has become a routine part of the evaluation of congenital heart disease and also part of the examination of patients with abdominal masses. Sonography should be the initial imaging modality in children at high risk for caval disorders. Previously used diagnostic procedures such as the inferior venacavogram should now be used only as a secondary investigative tool.

Echocardiography↗