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Biomedical subjects

T L Tewfik

Publications and source records attributed to T L Tewfik.

41 records · Page 3Linked to original sources

Lymphangioma in children.

The topic of lymphangioma is reviewed. Included in the text are the embryology, classification, clinical presentation, and treatment. Eight case reports are included. One case involved the skin, two presented with a submandibular mass, one had both a facial lymphangioma and a cystic hygroma of the floor of the mouth, and there are two cases of involvement of the tongue, and two cases of classical cystic hygroma of the neck. The rate of involution is probably higher than previously thought. Indications for surgery are suggested. This diagnosis must be considered in the differential diagnosis of a mass presenting in the head and neck of a child.

Adolescent↗

Adenoid cystic carcinoma of the larynx.

Adenoid cystic carcinoma, or cylindromas, constitute a large and distinct group of neoplasms with characteristic microscopic features recognizable in tissues as varied as the nasal passages, tongue, and bronchi. Cylindromas of the larynx are rare and only 60 cases have been reported in a review of the literature in 1977. In this report, a case of adenoid cystic carcinoma originating in the subglottic area of the larynx is discussed, with emphasis on the clinical and pathologic characteristics. In the past, the histogenesis of cylindroma has been the subject of considerable controversy, but recent light microscopic and ultrastructural studies strongly implicate the seromucinous glands of the respiratory and upper digestive tracts as the tissues from which these neoplasms derive. In general, cylindromas of the upper alimentary and respiratory passages are best treated by wide surgical excision. Some clinicians have combined surgery with postoperative radiation therapy in an attempt to prevent or delay recurrence and metastases. Chemotherapeutic agents have also been employed in the postoperative management of adenoid cystic carcinoma although the longterm results of this treatment modality remain to be determined.

Aged↗

Hemangiopericytoma of the temporal bone.

Hemangiopericytomas are uncommon soft tissue tumors. While their occurrence in sinuses and soft tissues around the ear is well documented, there are no reports of primary involvement of the temporal bone. This article discusses the case of a 21 year old patient who had a right temporal angioblastic meningioma resected and presented two years later with a hemangiopericytoma that extensively involved the right temporal bone and external auditory canal. In review, the "meningioma" had the same histological features as the auditory tumor and it was evident that both lesions resulted from the growth of a hemangiopericytoma arising from the intracranial aspect of the temporal bone. Electron microscopic examination of the tumor proved useful in making the diagnosis and in evaluating the cytological features that influence prognosis and treatment. Temporal bone involvement was a major problem and the opportunity is taken to document this rare occurrence and to discuss the biological behavior, pathological characteristics, and differential diagnosis of these neoplasms.

Adult↗

Ingestion of lye and other corrosive agents--a study of 86 infant and child cases.

Eighty-six cases of caustic ingestion seen over a 10 year period at the Montreal Children's Hospital are presented in an analytical retrospective fashion. All the patients were hospitalized. Ingestion was more common in males than females. Sixty-two patients were less than four years of age. Thirty-five of the 86 cases had esophageal burns. Esophagoscopy was performed on all cases. There was no perforation following endoscopy. Steroids and antibiotics were used on all the cases. Six patients developed stricture formation requiring bougienage.

Adolescent↗

Laryngeal stenosis following carbon dioxide laser in subglottic hemangioma. Report of three cases.

Recent reports recommend carbon dioxide laser as the safest and the most effective treatment for subglottic hemangioma in infants. Though one report mentions the development of a small amount of subglottic scarring in an 8-month-old girl after resection of a subglottic hemangioma, there is insufficient emphasis in the literature with respect to stenosis as a complication of CO2 laser therapy. The authors present three cases of severe laryngotracheal stenosis developing in infants treated with the CO2 laser for subglottic hemangioma. The presentation of these three cases should be a warning to the otolaryngologist that the use of the CO2 laser is not without significant risk of scar tissue formation.

Carbon Dioxide↗