Biomedical subjects
T López-Alburquerque
Publications and source records attributed to T López-Alburquerque.
Carpal tunnel syndrome and vitamin B6.
Twelve patients with carpal tunnel syndrome were studied. Clinical and electrophysiological data were obtained and an estimation of vitamin B6 (pyridoxine) status by an assay of erythrocyte aspartate aminotransferase and coenzyme stimulation assay were done. None of the patients was found to have vitamin B6 deficiency. Patients were treated with 150 mg of pyridoxine daily for 3 months. Erythrocyte aspartate aminotransferase increased significantly (p less than 0.001) in all the patients. In 6 patients there were clinical and electrophysiological improvement and erythrocyte aspartate aminotransferase increased more than in the other 6 patients. The data obtained appear to indicate that although vitamin B6 deficiency is not common in carpal tunnel syndrome patients, pyridoxine supplementation can be recommended as adjuvant treatment in those patients undergoing surgery.
Proximal sensory conduction in diabetic patients.
A study of segmental conduction along the peripheral afferent pathway of the upper limbs was carried out in 44 diabetic patients and 44 controls. An abnormal proximal conduction (Erb-cervical) was observed in 9 patients (20.4%). A similar incidence of abnormalities appeared at the most distal segment (digit III-wrist). A significant relationship between the alterations of proximal conduction and the presence of clinical signs of diabetic polyneuropathy was found. A common pathogenic mechanism underlying both these disorders is suggested.
Effect of ischaemia on somatosensory evoked potentials in diabetic patients.
The nerve action potential at the elbow and somatosensory evoked potentials (SEPs) at the scalp were recorded over 30 minutes of tourniquet-induced limb ischaemia in 10 diabetic patients and 10 controls. According to the SEP changes, an increased resistance to nerve ischaemia in diabetic patients was observed. The pathways involved in SEP conduction are discussed.
["Spindle coma": prognostic value].
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