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Biomedical subjects

T Lindh

Publications and source records attributed to T Lindh.

13 recordsLinked to original sources

Implant versus tooth-implant supported prostheses in the posterior maxilla: a 2-year report.

When implants are used for restoration of a jaw with a residual dentition, the possibility of combining implants with natural abutments may be considered. In a longitudinal comparative study, 26 patients (15 women & 11 men, age 49-84 years) with residual anterior dentitions were treated with two different designs of fixed partial dentures bilaterally in the posterior maxilla. On one side the reconstruction was supported by implants only, while on the contralateral side an implant and a tooth in combination were used. The patients were followed at intervals of 3, 6, 12 and 24 months after loading of the implants. 95 implants were placed, of which 11 non-loaded. A total of 10 implants failed, 7 prior to loading and three within the first three months of service (88.0+/-SE 6.7% cumulative survival for tested implants after two years' follow-up). There was no difference in failure rate for the implants in the two different prosthesis designs. The total mean loss of marginal bone height close to the implants was within acceptable standards, but was more pronounced at the implants not combined with teeth. The results indicate a correlation between the prosthesis design and the loss of marginal bone.

Aged↗

Surface contamination to UV-curable acrylates in the furniture and parquet industry.

Surface contamination to ultraviolet radiation curable coatings (UV coatings), used increasingly in the parquet and furniture industry, is a matter of concern as a source for skin contamination. UV coatings contain chemically and biologically reactive acrylates, well known as skin contact irritants and sensitizers. Surface contamination may spread secondarily to equipment and other unexpected areas even outside the workplace. Yet, studies concerning this type of contamination are lacking due to lack of suitable sampling methods. Surface contamination of the work environment with risk for skin exposure to UV coating was measured employing a quantitative adhesive tape sampling method developed for this purpose. A pilot study was first performed at three workplaces to evaluate the contamination. In the main study, we wanted to locate and identify in detail the surface contamination of areas where problems exist, and to determine the extent of the problem. Measurements were performed at seven workplaces on two separate workdays (round 1 and 2) within a six-month period. Samples were collected from the workplaces based on the video monitoring of skin contact frequency with the surfaces and categorized into three groups to analyze risk. The pilot study indicated that surface contamination to TPGDA containing UV coatings was common, found in 76 percent of the surfaces, and varied with a maximum of 909 microg TPGDA 10 cm(-2) sampling area. In the main study TPGDA was found in 153 out of 196 collected samples (78.1%); for round one 78.1 percent (82 out of 105 samples) and for round two 78.0 percent (71 out of 91 samples). The average TPGDA mass on positive surface samples was on the first round 2,247 +/- 7,462 microg, and on the second round 2,960 +/- 4,590 microg. We conclude that surface contamination to uncured UV coatings at UV-curing lines is common and this involves a risk for harmful, unintentional skin exposure to acrylates.

Acrylates↗

Immediate functional loading of Brånemark single tooth implants. An 18 months' clinical pilot follow-up study.

A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group = CG). The EG comprised 14 patients (= 14 implants) and the CG comprised 8 patients (= 8 implants), all with single tooth losses anterior to the molars. Beyond the non-smoking criterion the following criteria were adopted: i) the amount of bone had to allow for installation of a fixture with a minimum length of 13 mm and Ø = 3.75 mm, ii) the jaw relationship had to allow for bilateral occlusal stability, iii) the patients should be judged to be non-bruxers, and iv) the patients had to be available for the follow-up and maintenance programme. In the EG a temporary crown was connected to the implant within 24 h following fixture installation. Six months later this crown was replaced with a permanent one. In the CG the surgical and prosthetic treatment followed the standard protocol. Out of the 14 fixtures in the EG 2 were lost up to 5 months in function and were subsequently removed. All remaining 12 implants were stable at every subsequent follow-up examination. No fixture losses were recorded in the CG and all implants in this group were stable at the follow-ups. At the 6-month observation interval all the participating 20 patients were radiographically examined, an examination that was repeated at the 18-month follow-up. The analysis of the radiographs from the EG as well as from the CG disclosed that during the 12-month observation period the mean change of bone support was about 0.1 mm. Further studies, designed as controlled multicenter ones, have to be performed before the results of this pilot study can be recommended for more general use.

Adult↗

Workers' dermal exposure to UV-curable acrylates in the furniture and Parquet industry.

The use of ultraviolet radiation-curable coatings (UV-coatings) has increased rapidly in the parquet and furniture industry. Work with UV-coatings involves risk from skin exposure to chemically reactive, concentrated acrylates that are known skin contact irritants and sensitizers. Yet, the methods and tools for measuring and quantifying dermal exposure from hazardous chemicals directly on the skin are limited and methods to measure skin exposure to UV-coatings in occupational or environmental settings have been lacking. Skin exposure to UV-coatings was measured employing a quantitative tape stripping method that we have developed for this purpose. A pilot study was performed at three workplaces. In the main study, workers' skin exposure to uncured UV-coatings was measured at seven workplaces and on two separate workdays (rounds 1 and 2) within a six-month period to determine exposure variation. Skin exposure was measured at four standardized sites on the hand, 3-4 times per work shift. The forehead was sampled once. A questionnaire was carried out with the workers in both rounds to find out factors that can affect skin exposure to UV-coatings. The pilot study indicated that both skin and surface contamination to TPGDA-containing UV-coatings were common and varied up to 2110 microgram on the sampling area of 10cm(2). In the main study skin contamination due to TPGDA was found on 16 of 23 workers, at 6 out of the 7 workplaces, and from 36 (5. 4%) of the 664 samples. In round one 8.6% (n=383) of the samples contained TPGDA and in round two 1.1 % (n=281). The average TPGDA mass on all the positive samples (n=36) was 30.4+/-77.0 microgram for the first and second rounds alone this mass was 30.6+/-80 (n=33) and 28.3+/-16.5 microgram (n=3), respectively. Despite the limited sampling area and sampling sites, we could find residues of TPGDA at all sampling times, even at the beginning of the work shift. This may be due to transfer of UV-coatings through contaminated equipment, shoes and surfaces. Our study indicates that there is a risk of harmful skin exposure to UV-coatings in the furniture and parquet industry.

Acrylates↗

A method for measuring dermal exposure to multifunctional acrylates.

UV-curable acrylates are used increasingly for coating wood surfaces in the furniture industry. One of the active components, tripropylene glycol diacrylate (TPGDA), is known to be both an allergen and irritant to the skin. Methods to measure dermal exposure to skin irritants and allergens, such as acrylates, are insufficient for exposure assessment and there is none for this compound. The aim of this investigation was to develop a skin and surface sampling method, based on tape stripping, and a gas chromatographic method for quantitative analysis for assessing occupational skin exposure to multifunctional acrylates. Twelve adhesives were tested for their efficiency to remove TPGDA and UV-coating from a glass surface, the skin of guinea pigs and human volunteers employing the tape-stripping method in order to find the best performing tape. Variables that affect removal efficiency such as the applied dose and its retention time on the skin, tape adhesion time on the skin, and the number of strippings required to detect the contaminant from the skin were studied. Fixomull tape performed the best during sampling and analysis and had the most consistent removal efficiencies for the studied substances. The average removal efficiency with a single stripping at the 2 microliters TPGDA exposed skin sites was 85% (RSD = 14.1), and for UV-resin exposed sites 63% (RSD = 20.2). The results indicated that this method can be used for measuring dermal exposure to multifunctional acrylates efficiently, accurately, and economically. This method provides a sensitive and powerful tool for the assessment of dermal exposure to multifunctional acrylates both from the skin and from other contaminated surfaces in occupational field settings.

Acrylates↗

Occupational exposure to magnetic fields and brain tumours in central Sweden.

Occupations with exposure to magnetic fields were studied in a population-based case-control study of male glioma and meningioma in Central Sweden. The study included 84 cases of glioma, 20 cases of meningioma and 155 controls. Information about job titles was obtained by means of a questionnaire. Three different methods were used to classify exposure 1) 'electrical occupations', 2) assessment of magnetic fields by an electrical engineer, 3) job values based on magnetic field measurements at work sites for occupational groups. When analyses were based on 'electrical occupations' a relative risk (RR) of 1.0 (95% CI: 0.4-2.4) was seen for glioma and 1.8 (95% CI: 0.3-3.6) for meningioma. When analyses were based on measurements a relative risk of 1.9 (95% CI: 0.8-5.0) was seen for glioma and 1.6 (95% CI: 0.3-10.2) for those ever in an exposed job of an average mean value of > 0.4 microT. A larger number of individuals was classified as exposed, when exposure was based on measurements. Information was available regarding several potential confounders, but none of them seemed to be of any importance. Our conclusion is that the results based on magnetic field measurements give some support to the hypothesis that magnetic fields exposure may play a role in the development of brain tumours.

Adult↗

A meta-analysis of implants in partial edentulism.

A meta-analytic technique was used to estimate the survival of implants supporting bridges or single crowns in partially edentulous patients. A survey of the literature revealed 66 studies, published between 1986 and 1996. Nine studies on single implants and 10 studies on fixed partial dentures met the inclusion criteria for the meta-analysis. Data from a total of 2686 implants, 570 single crowns (SC) and 2116 in fixed partial dentures (FPD), were analyzed. In order to calculate annual survival rates for individual studies a life-table analysis was conducted. Maximum follow-up time ranged between 1 and 8 years. After 1 year the success rate was calculated to be at least 85.7% for FPD and 97.2% for SC. When the results from the FPD studies were pooled the survival rate was 93.6% after 6-7 years. The corresponding value for SC was 97.5%.

Chi-Square Distribution↗

Acute effects of ELF electromagnetic fields: a field study of linesmen working with 400 kV power lines.

The aim of the study was to investigate the possible acute effects of exposure to electric and magnetic fields. Twenty six experienced linesmen, aged 25 to 52, were studied during two working days while performing a simulated routine inspection of insulators on steel poles of a 400 kV power line. During one of the working days the inspection was performed on a power line in operation and on the other day the same procedure was performed on an identical power line, which was not in operation. The two days were found to be comparable with regard to the physical workload which, on the basis of heart rate measurements, was estimated to be high. Exposure to the electric and magnetic fields was measured using a device designed for on-worker sampling on each linesman. The mean exposure for the working day was estimated to be 2.8 kV/m (SD = 0.35) and 23.3 microT (SD = 4.2). The possible effects of exposure were studied using a battery of four automated performance tests, EEG, a mood scale, and a questionnaire to assess subjective symptoms. All workers were examined immediately before and after each workday. Furthermore, blood samples were collected for each subject on three different occasions during each workday. The battery of behavioural tests comprised a test of simple reaction time, a vigilance test, a test of short term memory (digit span), and a perceptual test (symbol digit). The four EEG recordings for each worker were judged blindly and sorted with regard to amount and stability of alpha activity. The blood samples were used for an analysis of possible changes during the workday with regard to the following hormones: thyroid stimulated hormone, luteinising hormone, follicle stimulating hormone, prolactin, cortisol, testosterone, and neopterin. Detailed analyses of the results using both parametric and nonparametric tests showed no statistically significant difference between the two conditions which could be attributed to exposure to electric and magnetic fields.

Adult↗

Comparison between two power-frequency electric-field dosimeters.

Two instruments, an EFEM meter and a BE-log meter, have been tested on people working in switchyards for voltages between 70 kV and 400 kV. The results from the BE-log meter correlate well with the short circuit currents through people connected to the ground. The EFEM meter showed lower measured doses than the BE-log meter, and the relation between the two instruments was around 0.6.

Electricity↗

Exposure of workers in the electric power industry to electric and magnetic fields.

A survey of 50 Hz electric and magnetic fields in the electric power industry has distinguished differences in exposure among the employees making it possible to compare health effects as a function of exposure. The workers that were most exposed to electric and magnetic fields were linemen and substation personnel who worked on facilities at operating voltages above 20 kV. On average, they were exposed to an electric field strength above 30 V/m for approximately 1.5 to 3 hours per day and to a magnetic flux density of around 1 to 2 microT. The least exposed group were linemen working in the 0.4 to 20 kV part of the network with exposure to a magnetic field of 0.10 microT. The electric field seldom exceeded 30 V/m.

Cohort Studies↗

Tooth-implant and implant supported fixed partial dentures: a 10-year report.

PURPOSE: The use of implants for prosthetic rehabilitation of partially edentulous patients is increasing. However, the possibilities of placing implants in the posterior part of the mandible are often limited. The purpose of this longitudinal study with 10 years of follow-up was to evaluate the use of short implants supporting fixed partial dentures (FPD) in the posterior part of the mandible, and to compare implant supported FPDs to tooth-implant supported FPDs. MATERIALS AND METHODS: The patient material comprised 23 patients with residual mandibular anterior teeth, and each patient received FPDs unilaterally. On one side the FPD was supported by two implants, and on the other side by one implant and one tooth, thus permitting intraindividual comparison. The distribution of the two types of FPDs in each jaw was randomized. Implant success rates, marginal bone changes, and mechanical complications were studied. RESULTS: The tooth-implant connection did not demonstrate any negative influences on the overall success rates for the 10-year period, nor were the shorter implants found to be less favorable. CONCLUSION: It is suggested that a prosthetic construction supported by both a tooth and an implant may be recommended as a predictable and reliable treatment alternative in the posterior mandible.

Alveolar Bone Loss↗

Tooth-implant supported fixed prostheses: a retrospective multicenter study.

PURPOSE: The purpose of this retrospective multicenter study on implants combined with natural teeth was to investigate the implant survival rate and loss of marginal bone, as well as indications and complications pertinent to this form of implant therapy. MATERIALS AND METHODS: The study comprised 185 implants in 111 patients from six different clinics in Sweden. Gathering of data, which were taken from patient records, followed a strict protocol. The registrations included indications for treatment, failure of implants, radiographs from baseline and follow-up, and information on complications. RESULTS: The cumulative implant survival was found to be 95.4% (standard error 4.5%) up to 3 years of follow-up. The marginal bone level at baseline was lower in the maxilla compared with the mandible (P = .015), but any further loss did not differ between the jaws. The most severe complication other than loss of osseointegration (6/185) or periimplant infections (4/183) was intrusion of the abutment teeth, which occurred in 5% of the cases. In all instances, the intrusion was seen in constructions with nonrigid forms of connection between the implants and teeth. CONCLUSION: The tooth-implant supported prosthesis using the Brånemark system is in the short term an equally predictable treatment as the completely implant-supported prosthesis concerning implant survival and loss of marginal bone. When combining implants and teeth, a rigid form of connection should be used to prevent tooth intrusion.

Aged↗

Rigid connections between natural teeth and implants: a technical note.

In the posterior partially edentulous jaw, implants may be used to supplement existing natural dentition. Frequently, the maxillary sinuses and the mandibular nerve preclude the fabrication of freestanding implant-retained prostheses. However, if an implant and a natural abutment are combined, a fixed prosthesis can be fabricated, restoring the arch into the premolar area. The histories of three patients with attachments connecting implant-retained ceramotitanium crowns with crowns on natural abutments are described. A design for a rigid custom-made attachment for the Brånemark system, using standard components with a machine-duplication, spark-erosion technique, is suggested.

Bicuspid↗