[Bronchiectasis in childhood].
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Biomedical subjects
Publications and source records attributed to T Loós.
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Mycoplasma pneumoniae infection could be found in 16 from 92 children treated for respiratory disease in a Hungarian hospital. It was verified by growth inhibition test or by culturing germs from bronchial secretions. Seroology proved to be more effective than culture for identification. Illnesses due to Mycoplasma pneumoniae seem to be more frequent in the age group 0--3 years in Hungary than they are in western countries in the same age group. The authors assume that this high frequency is caused because children in this country are earlier admitted to community facilities (crèche, kindergarten, hospital) than in western countries. Therefore mycoplasma pneumoniae infection must be paid attention to also in acute respiratory diseases in the first 3 years of life, when children are admitted to community facilities.
In 12 children aged 8 month to 5 years (in the average 2,3 years), respiratory illness caused by Mycoplasma pneumoniae, could be secured with microbiological methods (growth inhibition, cultivation). The most common clinical, roentgenological and laboratory signs are discussed. A disease from Mycoplasma pneumoniae should be assumed, when a child will begin to cough often with staccato attacks without apnoea at night and has temperature short time after adimission to a group. The findings by auscultation are small but the X-ray-picture is showing marked alterations. A precise diagnosis can be achieved only with microbiological examinations (serology or cultivation). When there are no symptoms and signs described above, the diseases caused by Mycoplasma pneumoniae can be detected only if Mycoplasma serology has become a routine laboratory task in institutions for paediatric bronchopneumology.
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Between 1972--1974 26 children (15 boys and 11 girls) aged 11--14, with sarcoidosis were observed in county Szabolcs-Szatmár, Hungary. The number of cases varied between 1--6 per year, so the incidence of sarcoidosis is about 2--11/100000 for the age group 10--14 years of this county. Sarcoidosis was detected because of complaints in 4 cases, and by mass radiographic surveys in 22 cases. In each of the patients the thoracic form of sarcoidosis was in the foreground (in 6 cases mild bilateral hilar adenopathy, in 2 cases only unilateral hilar adenopathy, in 18 cases typical BHL-syndrome sometimes with "tumorous" adenopathy and in 7 cases out of the 18, hilar adenopathy and mottling in the lungs). The laboratory data were an unsatisfactory basis for the diagnosis. The tuberculin test was negative in 65 per cent. There was no proof for infection with atypical mycobacteria by intradermal tests. The most important basis of diagnosis was the biopsy (mediastinoscopy), especially in cases of simultaneous infection with tuberculosis. Prednisone treatment was carried out in the first place in cases of adenopathy and mottling, and in the cases of elevated serum calcium. Prednisone resistance was observed in two cases; in one of the patients it was secondary since it manifested itself only at the relapse of the BHL-syndrome; in the other patient the drug resistance was primary.
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