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Biomedical subjects

T M Buckenham

Publications and source records attributed to T M Buckenham.

At least 55 records · Page 3Linked to original sources
PubMed1993

Infrapopliteal angioplasty for limb salvage.

Fourteen infrapopliteal angioplasties were performed in 13 patients with critical limb ischaemia. Clinical indications were rest pain, ulceration, gangrene or a critically ischaemic limb from a graft occlusion secondary to an infrapopliteal lesion. The average ankle-brachial ratio was 0.22 in non-diabetics. Technical success was achieved in all lesions with an average increase of Doppler ratios of 0.5. Of the 13 patients, 11 (85%) showed early clinical improvement (with average length of follow-up of 8 months, range 1-18 months). With the introduction of smaller lower profile catheters, hydrophilic and steerable wires and the advent of digital subtraction angiography, infrapopliteal angioplasty can now be performed successfully and with few complications. The presence of spasm should be aggressively treated with intra-arterial nitroglycerin or verapamil.

Aged↗
PubMed1993

The differences in early haemodynamic response between surgery and angioplasty after successful re-opening of the superficial femoral artery.

In 40 patients with superficial femoral artery disease we prospectively evaluated the effect of angioplasty (n = 20) or femoropopliteal bypass (n = 20) on the ankle-brachial pressure index (ABI) using the Doppler ultrasound probe. The ABI was measured as a baseline 1 day before the procedure, 1 day after the procedure and 30 days later. In the angioplasty group the baseline ABI was 0.57 (0.11), increasing to 0.74 (0.26) 1 day postangioplasty and increasing further to 0.88 (0.26) after 30 days. The increase in ABI over 30 days was significantly greater than the increase over 1 day. In the femoropopliteal bypass group the baseline ABI was lower at 0.46 (0.17). However 1 day postoperatively it had increased to 0.92 (0.2) with almost no further increase at 30 days [0.95 (0.17)]. We concluded that by contrast to a surgical bypass where there was a large improvement in the ABI over the first day, the ABI following angioplasty continued to improve significantly beyond the first day.

Aged↗
PubMed1992

Accelerated thrombolysis using pulsed intra-thrombus recombinant human tissue type plasminogen activator (rt-PA).

The efficacy of regional thrombolysis for treating leg ischaemia is well established, but the duration of infusion and the frequent complications remain major disadvantages. By delivering recombinant human tissue type plasminogen activator (rt-PA) as pulsed intra-thrombus 5-mg aliquots combined with catheter manipulation to maintain an intra-thrombus location, the average time taken to achieve thrombolysis in 20 consecutive patients with infra-aortic occlusions was 109 min. Immediate thrombolysis was achieved in every case. Pulsed delivery of high dose rt-PA significantly accelerates thrombolysis, decreases dose and reduces costs.

Adult↗
PubMed1992

Thrombolysis and the femorofemoral bypass graft: a new technique.

Two patients with acutely thrombosed femorofemoral bypass grafts are presented. Recombinant human tissue-type plasminogen activator (rt-PA) was used successfully in thrombolysis of the occluded grafts. Utilizing a new technique the grafts were punctured directly and bolus doses of rt-PA administered.

Aged↗
PubMed1992

Accelerated thrombolysis facilitated by direct puncture of occluded prosthetic femoral grafts.

Inability to access occluded grafts is a major limitation to successful thrombolysis and may even preclude it. This paper addresses the problem and offers a new technique of direct puncture of prosthetic grafts through which thrombolysis and angioplasty can be performed. These techniques resulted in accelerated thrombolysis in all 15 patients studied with no failures due to inability to attain graft access.

Angioplasty, Balloon↗
PubMed1991

The recalcitrant subclavian pseudoaneurysm: a case report.

A case of pseudoaneurysm of the left subclavian artery is presented. It demonstrates not only the difficulties facing the surgeon and radiologist in the management of this rare condition, but also how interventional radiology and surgery can be used in tandem to approach such a complex vascular problem.

Aged↗
PubMedDate not supplied

Evaluation and complications of direct graft puncture in thrombolysis and other interventional techniques.

PURPOSE: To evaluate the value and complications of direct graft puncture in conducting interventional procedures in synthetic vascular bypass grafts. METHODS: We retrospectively reviewed 65 direct graft punctures in 50 patients undergoing a variety of interventional vascular procedures. In two patients the grafts were found to be infected and the procedures abandoned. RESULTS: Complications encountered included hematomas that did not require treatment in three patients, and four hematomas requiring surgical drainage. One graft became infected (despite prophylactic cefuroxime), after three consecutive punctures over a 10-day period for a variety of interventions. All the patients who developed hematomas had undergone pharmacological thrombolysis. CONCLUSION: Direct graft puncture is a relatively safe technique, with a minimal risk of infection and hemostatic complications attributable to thrombolysis. In 31 of the 41 patients undergoing successful thrombolysis, additional percutaneous procedures were undertaken, and these were facilitated by the direct graft puncture route.

Aged↗
PubMedDate not supplied

Endoluminal embolization of bilateral atherosclerotic common iliac aneurysms with fibrin tissue glue (Beriplast).

The standard surgical approach to nonleaking iliac aneurysms found at repair of a leaking abdominal aortic aneurysm is to minimize the operative risk by repairing the abdominal aorta only. This means that the bypassed iliac aneurysms may have to be repaired later. As this population of patients are usually elderly with coexisting medical problems, interventional radiology is being used to embolize these aneurysms, thus avoiding the morbidity and mortality associated with further general anesthesia and surgery. Various materials and stents have been reported to be effective in the treatment of iliac aneurysms. We report the successful use of endoluminal fibrin tissue glue (Beriplast) to treat two large iliac aneurysms in a patient who had had a previous abdominal aortic aneurysm repair. We discuss the technique involved and the reasons why we used tissue glue in this patient.

Aged↗
PubMedDate not supplied

The role of transradial diagnostic angiography.

PURPOSE: To evaluate the use of 4 Fr radial artery catheters as an alternative to both transbrachial and transfemoral approaches. METHODS: Seventy examinations were performed via the transradial route using 4 Fr 130-cm-long pigtail catheters. Prior to puncture the radial artery was assessed with pulse oximetry to ensure that it did not contribute the dominant blood supply to the hand. Patients were reassessed for complications within 24 hr of the procedure. RESULTS: Acceptable images were obtained in femoral arteriography, arch aortography, and selective carotid studies. In three of six renal arteriograms, images were suboptimal. There was a total technical failure rate of 5.7%. Significant complications were encountered in 4.3%, but no hand ischemia occurred. CONCLUSION: The transradial route for arteriography is easy to learn and has a low complication rate. It is a reasonable alternative approach to transfemoral arteriography for true outpatient peripheral angiography and in cases where the transfemoral route is not feasible, though it did not prove satisfactory for renal arteriography in hypertensive patients.

Adult↗