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Biomedical subjects

T M Darbinian

Publications and source records attributed to T M Darbinian.

15 recordsLinked to original sources
PubMed1976

[Comparative characteristics of the serotonin and histamine content in the blood of surgical patients before and after antibiotic administration against a background of droperidol, promedol and atropine premedication].

The effect of intramuscular administration of ceporin and megacillin in single doses of 500 mg and 1000000 Units respectively on serotonin and histamine blood levels in 34 patients against the background of premedication with droperidol, promedol or atropine was studied. The observations showed that after megacillin injection the serotonin blood levels decreased. Ceporin had no effect on serotonin and histamine blood levels.

Adolescent↗
PubMedDate not supplied

[Comparative study of the sedative and tranquilizing effect of phenazepama and seduxen and their influence on human evoked brain potentials].

Phenazepam was compared to diazepam in a double-blind study made in 32 patients. The drugs were administered by month in doses of 0.0025 mg/kg and 0.005 mg/kg. respectively 1--2 days before surgery with the use of general anesthesia. Anxiety assessed by means of the brain evoked potential test and by a clinical test according to Gologorsky's scale reduced 2 hours following both phenazepam and diazepam administration. Phenazepam elicited a more pronounced and more lasting tranquilizing effect as compared to that of diazepam. Phenazepam was concluded to be a powerful anxiolytic and sedative agent recommended for premedication before surgical interventions.

Anti-Anxiety Agents↗